[PDF] Top 20 Mutational analysis of delta antigen: effect on assembly and replication of hepatitis delta virus.

... Taken together, these results indicate that a subdomain from amino acid residues 50 to 65 as well as a signal within the N-terminal 50 amino acid residues of large HDAg may be important [r] ... See full document

... Hepatitis delta virus (HDV) genome is a circular, single- stranded, viroid-like RNA of ...25). Hepatitis delta antigen (HDAg), the only protein encoded by HDV RNA, is localized ... See full document

... Hepatitis delta virus (HDV), a satellite virus of hepatitis B virus, contains a circular RNA genome of ...protein, hepatitis delta antigen (HDAg) (18). In ... See full document

... RNA replication, although there are other ...of virus is a ...immunodeficiency virus type 1 ...the virus in the target cell, and without phosphorylation, the reverse transcription process ... See full document

... Hepatitis delta virus (HDV) causes chronic and, occasion- ally, fulminant hepatitis in humans ...satellite virus which requires hepatitis B virus (HBV) to supply en- ... See full document

... epatitis delta virus (HDV) is a unique human pathogen that increases the severity of liver disease in those infected with its helper virus, hepatitis B virus ...Genome ... See full document

... Hepatitis delta virus (HDV) is a satellite virus and requires the presence of hepatitis B virus (HBV) for virus assembly and production ...helper virus, HBV, ... See full document

... Hepatitis delta virus (HDV) is a small RNA virus that is found in nature uniquely associated with human hepatitis B virus (HBV), and coinfection with HDV often increases the ... See full document

... the replication cycle of hepatitis delta virus (HDV), RNA editing occurs at position 1012 on the 1679-nucleotide RNA ...the delta antigen ( d ... See full document

... the effect of HDAg expression on an HDV cDNA polyadenylation signal ...RNA replication is not de- pendent on the suppression of mRNA transcription by ...RNA replication and subgenomic mRNA ... See full document

... HDV replication following introduction of a ...ongoing replication or viral mutations that abrogate the growth-retarding effects of such ...negative effect of HDV infection on cellular growth or ... See full document

... Hepatitis delta virus (HDV) is a subviral pathogen that can self-replicate but relies on its helper hepatitis B virus to pro- vide envelope proteins for HDV infection and virion ... See full document

... RNA replication (5, 6, ...RNA replication, a situ- ation that does not reflect the delayed appearance of this protein in natural ...RNA replication can be established despite the fact that HDV ... See full document

... the effect of partial digestion with sodium carbonate on the migration pattern of the RNA in a denaturing acrylamide gel (53) and by RT-PCR amplification across the ligation ... See full document

... among hepatitis delta virus (HDV) isolates have focused principally on phylogenetic analysis of sequences, which vary by 30 to 40% among three genotypes and about 10 to 15% among isolates of ... See full document

... nome replication could be initiated in avian cells transfected with expression vectors containing wild-type HDV ...simian virus 40 late promoter, we did not detect even expression of the delta ... See full document

... an effect of the bacterial ex- ...deletional analysis (18–20, ...deletional analysis of the RNA requirements for binding indi- cated that binding is not determined by just one or two unique local ... See full document

... Chronic hepatitis delta (CHD) is a serious cause of viral hepatitis throughout the world, with high morbidity and mortality rates ...by hepatitis delta virus ...showing ... See full document

... Background: Hepatitis delta virus (HDV) ribozyme is an attractive molecular tool that can specifically recognize and catalyze the self-cleavage of the viral RNA phosphodiester ...in hepatitis ... See full document

... d Ag-L. Figure 2B shows that a similar staining pattern was obtained with the antibody specific for peptide K; for conve- nience, we will subsequently refer to this antibody as domain K. Clearly the immunofluorescence ... See full document