[PDF] Top 20 Original Article XB130 expression in human osteosarcoma: a clinical and experimental study

... Previous study provides evidence that XB130 is regulated by the actin cytoskeleton, and it impacts key cyto- skeletal functions, such as cell migration and invasion ...[17]. XB130 is also involved in ... See full document

... of osteosarcoma treatment failure are lung metastasis and its recurrence ...our study, we found that CD133 expression was positively related to lung metastasis, recurrence, and Enneking ...CD133+ ... See full document

... that expression of chemokine (C-C motif) receptor-like 2 (CCRL2) is associated with ...CCRL2 expression with bladder cancer remains un- ...present study was to investigate the clinical ... See full document

... NIBP is a novel NIK and IKKβ-binding protein that enhances NF-κB activation, Both IKKβ and NF-κB are play an important role in regulating tumorigeness [23, 27-29]. NIBP promotes tu- morigenesis via NFκΒ signaling in ... See full document

... the expression of MEK5 in hepatocellular carcinoma ...MEK5 expression and the clinical outcome of the disease remains poorly ...present study, MEK5 mRNA and protein expression in HCC ... See full document

... miR-761 expression levels in OS tis- sues and cell lines was lower than those in adjacent normal tissues and normal cell ...the expression of CXCR1 in OS tissues was higher than in adjacent normal tissues, ... See full document

... Altered expression of microRNAs (miRNAs) has been implicated in the initiation and progression of ...including osteosarcoma (OS). However, the clinical significance of miR-26b is poorly ...the ... See full document

... cific binding blockage with 5% bovine serum albumin, slides were incubated in rabbit poly- clonal Zeb1 antibody (Sigma-Aldrich) at 1:200 dilution polyclonal anti-human Zeb2 antibody (Abcam) at 1:150 dilution ... See full document

... several human can- cers [18–20]. Recently, aberrant miR-452 expression has been demonstrated in glioma [21], non-small cell lung cancer (NSCLC) [22], bladder cancer [23], prostate can- cer [24], urothelial ... See full document

... protein expression or mutation was being ...protein expression as nuclear staining in at least 10% of tumor cells, a standard used by most studies ...The clinical outcome used was mortality of the ... See full document

... high expression of Nuclear factor erythroid 2-related factor 2 (Nrf2) is associated with cancer growth and ...this study, we investigated expression of Nrf2 and NQO1 in gastric cancer and its ... See full document

... in osteosarcoma (OS) ...this study was to evaluate the effects of NVP-BKM120 (BKM120), a selective pan-class I PI3K inhibitor, on OS in vitro and ...P-AKT expression without effecting total AKT in ... See full document

... or expression disorder of HER2 will be activated by some carcinogenic factors which make HER2 owns tumor transfor- mation activity so that it can promote malig- nant transformation of cells ...abnormal ... See full document

... Abstract: Osteosarcoma (OS) is a kind of high-grade bone-forming malignancy with poor prognosis, causing huge economic losses to the patients and ...of osteosarcoma by the differentially expressed miRNAs ... See full document

... the expression and function of NEAT1 on osteosarcoma (OS) have not been studied ...relative expression level of NEAT1 was determined by qRT-PCR in a total of 37 patients with ...NEAT1 ... See full document

... This study aims to (1) evaluate the immunohistochemical expression of ERα, ERα36 and ERβ in combina- tion in human renal cell carcinoma (RCC) and nearby non-tumorous tissue (2) correlate their ... See full document

... Abstract: Osteosarcoma (OS) is the most common primary malignant bone tumor that has poor ...This study investigates the expression of Sox9, Wnt1 and Fzd1 in human osteosarcoma tissues ... See full document

... the expression of MMPs plays cru- cial role in OS development and to be signifi- cant prognostic factor for the disease free survival of patients with OS, for example, MMP-9 expression has been reported to ... See full document

... peutic clinical drugs ...the expression and role of TAK1 in OS. In the present study, we first ana- lyzed the expression and clinical significance of ... See full document

... seeded into each well, in a minimum of six wells. A row of 8 wells exposed only to the RPMI- 1640 medium was used as a control. Twenty- four hours following cell seeding, IM was added to the experimental wells ... See full document