[PDF] Top 20 Original Article Immunohistochemical expression of LAPTM4B in clear cell renal cell carcinoma by tissue microarray

... proto-oncogene, LAPTM4B was initially identified in hepatocel- lular carcinoma cells and it plays critical roles in proliferation and metastatic potential of vari- ous tumors ...[1]. LAPTM4B protein ... See full document

... localized clear cell renal cell carcinoma ...Methods: Tissue microarrays of 74 cases of ccRCC without distant metastasis or invasion were performed by CD147 and HIF-2α ... See full document

... cancer tissue and normal tissue using TRIzol Reagent (TaKaRa, Dalian, ...gene expression levels were calculated using the ΔCt method normalized to the endogenous gene ... See full document

... PGAM1 expression was found in both normal kidney and CCRCC, but the high-expression rate of PGAM1 in CCRCC was significantly high- er compared with those in normal ...hepatocellular carcinoma, oral ... See full document

... in clear cell renal cell carcinoma remains ...in clear cell renal cell ...Methods: Immunohistochemical staining was performed in samples from 288 ... See full document

... Total RNA was extracted from the tissues using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) in accordance with the manufacturer’s instruc- tions, and was then used for the synthesis of first strand complementary DNA ... See full document

... The Kaplan-Meier analysis and log-rank test were used to investigate the prognostic value of SIRT4 levels for patient survival. In univariate analysis, we found that age, tumor size, patho- logical grade, and T, N and ... See full document

... its expression profile and its prognostic value in clear cell renal cancer (ccRCC) have not been ...Methods: Expression of the Argonaute proteins were assessed by im- munohistochemistry ... See full document

... in renal clear cell carcinoma, as well as its clinical ...the expression of EMMPRIN in primary ccRCC clinical specimens and cell lines; as a result, EMMPRIN was knocked down in ... See full document

... IL-13 expression needs to be validated in other populations and larger ...IL-13 expression in metastatic RCC (mRCC) is not analyzed owing to limited cases with ...high expression of IL-4 and IL-13 in ... See full document

... abnormal expression of lysyl oxidase-like 2 (LOXL2) has been reported and is considered to play an important role in several cancers, such as breast and pancreatic cancer and esophageal squamous cell ...the ... See full document

... have been identified [9]. CT antigens are named after their pattern of expression, as they are found in various types of cancers but only in testicular germ cells of normal adult tissues [10]. Because of this ... See full document

... different expression of CHD9 in cancer and in the adjacent tissues was evaluated by NPar ...CHD9 expression in cancer and adjacent tis- ...CHD9 expression were also analyzed by Spearman’s correlation ... See full document

... proven renal cancer with follow-up information were conducted a systematically analysis to confirm the relationship of the PP2A proteins and outcome of patient ...tumor tissue had a better over- all ... See full document

... whose original pathological specimens were available for Western blot and quantitative polymerase chain reaction ...The tissue microarrays were obtained from Shanghai Outdo Biotech, Shanghai, People’s ... See full document

... a renal tumor were enrolled in our study at the Department of Urology, Harbin Medical University Cancer Hospital from 2013 to ...as clear cell RCC and by post-operative ... See full document

... EGFR is a transmembrane glycoprotein with receptor tyrosine kinase (RTK) activity and reg- ulates cell proliferation, differentiation, and apoptosis. EGFR mutations increase its kinase activity, which leads to ... See full document

... Abstract: The management of renal cell carcinoma (RCC) has evolved considerably in recent years. This report represents the consensus of 22 relevant medical specialists from Africa and the Middle ... See full document

... Gene Expression Omnibus (GEO), and TCGA data portal) and curated to form a comprehensive RCC transcriptome ...gene expression profiling of 295 tissue samples obtained from six GEO data sets ... See full document

... all renal tumors occurring in young adults ...end-stage renal disease (ESRD) and acquired cystic disease (ACD) [1, 6-9, ...other renal tumors has been described including clear cell ... See full document