[PDF] Top 20 Original Article Overexpression of IL-9 receptor in diffuse large B-cell lymphoma

... its receptor (IL-9R). Recently, the oncogenic activities of IL-9 and IL-9R were reported in some lymphomas but not diffuse large B-cell lymphoma ...of ... See full document

... Plasmablastic lymphoma (PBL) is a rare type of diffuse large B-cell lymphoma (DLBCL) that was originally reported in the oral cavity of HIV-positive ...The cell ... See full document

... TMAs were cut into 4 μm sections, deparaf- finized and rehydrated through graded alcohol series. Slides were pretreated in the microwave with citrate buffer (pH 6.0) at 90°C for 10 min to retrieve antigen, immersed in 3% ... See full document

... From Mar 2006 through Jan 2016, a total of 99 consecutive patients with newly diagnosed GI-DLBCL were reviewed in the retrospective study. The patients’ clinical and pathological fe- atures were summarized in Table 1. ... See full document

... in diffuse large B cell lymphoma (DLBCL) and its prognostic ...with B symptoms, IPI score, CHOP-like treatment and Rituximab (all ... See full document

... of lymphoma [4, ...kine IL-9 was initially described as a growth factor se- creted by activated Th2 ...γC-family receptor on target cells and has diverse functions in im- mune and inflammatory ... See full document

... a large number of patients with pros- tate cancer, Zang et al reported the abnormally high expression of B7-H4 in tumor tissues with positive expression rates of 99% ... See full document

... with large samples, except 3 reports of rare cases ...whether lymphoma was localized within the thyroid gland or ...from large data that in patients with autoimmune rheu- matic diseases ... See full document

... Wirk B, Fenske TS, Hamadani M, Zhang MJ, Hu ZH, Akpek G, Aljurf MD, Armand P, Ayala E, Bachanova V, Bolwell B, Cairo MS, Cashen A, Chen YB, Costa LJ, Farhan S, Freytes CO, Ga- jewski JL, Gibson J, Hale GA, ... See full document

... Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoid neoplasm, accounting for 25-30% of all new non-Hodgkin lymphoma (NHL) diagnoses in the west and ... See full document

... phoma showed great potential value for XPO1 research [43]. Inhibitors of XPO1 prohibited the proliferation of NHL cells and induced their apoptosis by down-regulating anti-apoptotic proteins, such as Survivin and NF-κB ... See full document

... risk extranodal sites [9]. Accumulating with age has shown to confer a poor prognosis in DLBCL, and at diagnosis of DLBCL ageis found to cor- relate with the molecular profile of genetic alterations such as MYC or ... See full document

... about overexpression of the transcription factors of EMT in solid tumors which are related with increased ...squamous cell carcinoma of the head, breast cancer and so on [14, 33, ... See full document

... exert cell apop- tosis antagonizing effects via impeding self- activation of caspase-3 and ...with cell cycle regulatory pro- tein CDK4 to form Survivin/CDK4 complex, which dissociates CDK4/p21 to release ... See full document

... status (PS), and serum lactate dehydrogenase (LDH) levels have been reported to be associ- ated with prognosis [7-9]. Treatments for PG-DLBCL include rituximab plus anthracycline- based combination chemotherapy, ... See full document

... strong B, Cozen W, Linet M, Bosch FX, Ennas MG, Holford TR, Gallagher RP, Rollinson S, Bracci PM, Cerhan JR, Whitby D, Moore PS, Leaderer B, Lai A, Spink C, Davis S, Bosch R, Scarpa A, Zhang Y, Severson RK, ... See full document

... human diffuse large B-cell lymphoma (DLBCL) remains ...DLBCL cell lines (DB and SU-DHL-4) as compared to normal human peripheral blood lymphocytes using quantitative RT-PCR and ... See full document

... indicating cell cycle arrest, levels of anti-apoptotic genes including BCL-XL and BCL-2 decreased, and levels of pro-apoptopic genes including BAX, BAK, and NOXA increased ...κ B p50 and p65 DNA-binding ... See full document

... Chris Hani Baragwanath Academic Hospital (CHBAH) is a large, tertiary, public sector, University of the Witwatersrand linked hospital, located in Soweto, Johannesburg. The first patient with HIV-NHL at CHBAH, was ... See full document

... detected in four of 16 cases (25%; Fig. 2a), which included two ELD, one T-cell lymphoma, and one low-grade B-cell lymphoma. A cytosine-to-thymidine mutation was found in a DNA fragment ... See full document