[PDF] Top 20 Original Article Programmed cell death 2 functions as a tumor suppressor in osteosarcoma
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Original Article Programmed cell death 2 functions as a tumor suppressor in osteosarcoma
... UMR106 cell line. The cell viability and invasion ability were ...cancer cell viability and invasion ability, indicating that PDCD2 might be function as a potential tumor suppression ... See full document
7
MicroRNA-138 functions as a tumor suppressor in osteosarcoma by targeting differentiated embryonic chondrocyte gene 2
... a tumor suppressor gene in various types of ...suppressed cell invasion and led to cell cycle arrest and apoptosis ...suppress cell invasion and metasta- sis by targeting SRY-box 4 ... See full document
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Original Article miR-196 acts as a tumor suppressor in osteosarcoma by targeting HOXA9
... The development of combined therapy meth- ods and surgical procedures over the past decades has greatly improved the 5-year over- all survival of osteosarcoma (OS) patients [1-3]. However, it is still unfavorable ... See full document
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Original Article Bone morphogenetic protein 9 is a potential tumor suppressor in osteosarcoma
... for cell proliferation analysis using CCK-8 ass- ay (YEASEN) following the manufacturer’s ...instructions. Cell Counting Kit-8 (CCK-8) allows very convenient assays by utilizing Dojindo’s highly ... See full document
7
Original Article miR-143-3p functions as a tumor suppressor by targeting HK2 in neuroblastomas
... inducing cell cycle arrest of triple-negative breast cancer (TNBC) cells via negative modulation of LIM domain kinase 1 (LIMK1) at mRNA and protein levels ...squamous cell carcinoma (ESCC) and has been ... See full document
11
Original Article MiR-433 functions as a tumor suppressor in glioma cells by regulating YAP1
... a tumor suppres- sor in gastric cancer [23], liver cancer [24] and myeloproliferative neoplasms ...the cell viability, migration and inva- sion but promoted cell apoptosis in this study indicating ... See full document
8
Original Article microRNA-9 functions as a tumor suppressor in colorectal cancer by targeting CXCR4
... CRC cell lines (LOVO, SW620, HT29, DLD-1, and HCT116) and a normal colon- ic cell line (NCM460) were obtained from the Shanghai Institute for Biological Sciences (Shanghai, China) and American Type Culture ... See full document
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Original Article MiR-181d functions as a potential tumor suppressor in oral squamous cell carcinoma by targeting K-ras
... squamous cell carcinoma (OSCC) is one of the most frequent carcinomas all over the world, and the mechanism of its progression remains poorly ...the cell viability and apoptosis were ...mediated ... See full document
9
Original Article Inhibition of cell migration and invasion and promotion of cell apoptosis by overexpression of programmed cell death 4 (PDCD4) in cervical cancer Siha cells
... that programmed cell death 4 (PDCD4), a new tumor suppressor, participates in the tumorigenesis and progression of various ...on cell migration, invasion, and apoptosis of ... See full document
8
Original Article MiR-381 functions as a tumor suppressor in gastric cancer by targeting ROCK2
... GC cell lines (SGC7901, MGC803, BGC- 823, AGS and MKN45) and the gastric epithe- lial cell line GES-1 were purchased from the Type Culture Collection of the Chinese Acade- my of Sciences (Shanghai, People’s ... See full document
9
Original Article MicroRNA-29 family functions as a tumor suppressor by targeting RPS15A and regulating cell cycle in hepatocellular carcinoma
... To determine whether RPS15A is direct target of miR-29 family, wild-type and mutant 3’-UTR lacking miR-29 binding sites were cloned into the downstream of firefly luciferase coding region in pGL-3 luciferase reporter ... See full document
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Original Article Down-regulation of programmed cell death 4 (PDCD4) associates with the progression of cervical cancer
... Abstract: Programmed cell death 4 (PDCD4) is a tumor suppressor, and it inhibits tumor progression and metasta- sis. Even though down-regulation of PDCD4 has been implicated with ... See full document
8
Original Article Semaphorin-3F functions as a tumor suppressor in colorectal cancer due to regulation by DNA methylation
... regulate cell inva- sion and metastasis could lead to the develop- ment of new anticancer therapies for CRC ...SW620 cell invasion and colony ...SW620 cell line after treatment with 5-Aza-CdR (5 or ... See full document
9
Original Article MicroRNA-129-3p functions as a tumor suppressor in serous ovarian cancer by targeting BZW1
... well documented that normalizing or correct- ing the aberrant miRNAs could return a cell or organ from a pathological state to its normal phenotype [16, 17]. In our previous study, we identified the deregulated ... See full document
8
Original Article miR-137 functions as a tumor suppressor gene in pituitary adenoma by targeting AKT2
... a tumor suppressor gene in CRC ...squamous cell carcinoma, and the methylation status was associated with prognosis ...and tumor growth in ...blastoma cell lines decreased cell ... See full document
8
Original Article MicroRNA-223-3p functions as a tumor suppressor by regulating cell cycle in hepatocellular carcinoma
... To address the molecular mechanisms involved in miR-223-3p in inhibition of proliferation and invasion, we searched for potential target ge- nes with an established or potential function in HCC. Interestingly, a perfect ... See full document
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Original Article miR-455-3p functions as a tumor suppressor in colorectal cancer and inhibits cell proliferation by targeting TPT1
... including cell proliferation, migration, and apop- tosis has been recognized ...non-small cell lung cancer, and esophageal squamous cell carcinoma, suggesting that miR-455-3p functions as a ... See full document
8
Original Article MicroRNA-584 functions as a tumor suppressor and targets PTTG1IP in glioma
... determine cell viability and proliferative capacity, cells were examined using the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) and colony formation assays as described ... See full document
10
Original Article Programmed cell death 4 (PDCD4) repression is involved with tumor cell differentiation and lymph node metastasis in patients with colon cancer
... Abstract: Programmed cell death 4 (PDCD4), a novel tumor suppressor, inhibits neoplastic transformation and tumor progression, and is downregulated or even lost in various types ... See full document
5
Temporospatial patterns of apoptosis in chick embryos during the morphogenetic period of development
... of cell death in Xenopus tail buds as less defined than the pattern seen in other tissues, coupling this less well defined pattern with the random cell death seen at gastrulation in ... See full document
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