[PDF] Top 20 Polypeptides of the Epstein-Barr virus membrane antigen complex.

... That these polypeptides are genuine membrane proteins is indicated from several lines of evidence: first, they are found associated with a highly purified plasma membrane fraction; secon[r] ... See full document

... ternary complex of transcription factors in real-time within the nucleus of the cells has been described ...LMP1-signaling complex are identified, the assembly of the LMP1-signaling complex in real- ... See full document

... 465 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest A bacterially synthesized 28-kilodalton carboxyl-terminal fragment 28K-EBNA of Epstein-Barr virus nuclear antigen sh[r] ... See full document

... The isolation and biochemical characterization of these EBV mem- Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The Epstein-Barr virus EBV-associated membrane antigen [r] ... See full document

... Epstein-Barr virus (EBV) is a DNA tumor virus that is associated with the pathogenesis of endemic Burkitt’s lym- phoma, Hodgkin’s lymphoma, and posttransplant ...nuclear antigen 2 ... See full document

... protein level can be regulated through polyubiquitination (23). Interestingly, EBNA3C has been previously shown to utilize a ubiquitin-mediated proteasome degradation strategy for target- ing and degrading multiple tumor ... See full document

... the virus ge- nome in the nucleus, only speculation based on what is known for other ...the virus envelope and cell pro- teins have important consequences for postfusion events, but how they may impact ... See full document

... Inhibition of'25I-proteinA binding to membrane antigen-positive Raji cells after absorption of three different dilutions of the antibody-positive serum with a papain extract prepared fro[r] ... See full document

... that contacts various proteins of the basal transcription ma- chinery (54, 55). Since activation of Notch is associated with several types of cancer (13, 59), the interaction of EBNA-2 with J␬ is likely to play an ... See full document

... VCA complex, BcLF1, BALF4, BdRF1, and BFRF3, had all been detected in viral particles (4, 13, ...early antigen, but the virions did not react with these antisera (data not ... See full document

... A membrane immunofluorescence MF assay employing TPA-induced P3HR-1, an EBV-transformed human cell line, was used to screen for hybridomas producing antibody to EBV MA.. Hybridomas were [r] ... See full document

... Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA-3C) is one of five viral nuclear proteins that are essential for EBV-induced immortalization of primary human B lymphocytes in ...latent ... See full document

... i Acute transfection and expression of EBNA-2 under control of simian virus 40 or Moloney murine leukemia virus promoters resulted in increased LMP1 expression in P3HR-1-infected Burkitt[r] ... See full document

... In contrast, the cells infected with the P3HR1 Epstein-Barr virus strain, a deletion mutant that cannot encode Epstein-Barr nuclear antigen 2 EBNA2 or a full-length EBNA-LP, expressed EB[r] ... See full document

... One monoclonal antibody, designated R3, was directed against a diffuse component of the early antigen complex since it reacted by immunofluorescence with cells fixed in acetone or methan[r] ... See full document

... The ative amount of radioactivity incorporated into three glycoproteins are neither induced in nor surface glycoproteins with molecular weights of precipitated from the EBV-negative cell[r] ... See full document

... Fracture immunolabeling of B95-8 cells with BMA-17 monoclonal antibody: a dense and uniform labeling over the unfractured surface of a virus-producing cell; b incomplete fracture crack o[r] ... See full document

... ment observed in the [3H]proline pulse-chase analysis, we performed immunoprecipitations with the S12 antibody on membrane and cytoplasmic fractions from the EBV+ BL line Jijoye and the [r] ... See full document

... 171 is an EBV-immortalized LCL derived from the same pa- tient as BL41. The second set consists of Mutu I and Mutu III (16). These are two sublines from an EBV-positive BL tumor. Mutu I expresses only the EBNA1 viral ... See full document

... These experiments indicated that i at least 30% of the cytoplasmic LMP is in the plasma membrane, as opposed to other membrane compartments of the cell, ii the amino- terminal, carboxy-t[r] ... See full document