[PDF] Top 20 The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region.
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The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region.
... 1265 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The study of expression of several human immunodeficiency virus type 1 proviral mutants in human cells in the prese[r] ... See full document
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Efficient expression of the human papillomavirus type 16 L1 protein in epithelial cells by using Rev and the Rev-responsive element of human immunodeficiency virus or the cis-acting transactivation element of simian retrovirus type 1.
... To construct pNLCATW, the chloramphenicol acetyltransferase (CAT) gene was PCR amplified with the oligonucleotides CATS (5 9 -GCTAAGGAAGCTA AAATGGAG-3 9 ) and CATA (5 9 -CTATTAGGCCCCGCCCTGCCACTC-3 9 ) and subsequently ... See full document
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cis-acting elements in human immunodeficiency virus type 1 RNAs direct viral transcripts to distinct intranuclear locations.
... potential cis determinants of the intranuclear local- ization of HIV gag RNA, we constructed a subgenomic gag- expressing plasmid, pCMVgag-2 ...RNA expression by Northern blotting revealed two distinct RNA ... See full document
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cis-acting sequences involved in human immunodeficiency virus type 1 RNA packaging.
... RNA expression and ...39 env region for encapsidation, although deletion of the entire region significantly inhibited ...entire env gene and being expressed at adequate levels in the ... See full document
5
cis-Acting inhibitory elements within the pol-env region of human T-cell leukemia virus type 1 possibly involved in viral persistence.
... CAT transcripts, indicating that the fragments may function at the transcriptional level. This inference is supported by the observation that the effects of the fragments showed no orien- tation dependence. However, when ... See full document
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Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region.
... A 1.1-kb env gene fragment encompassing the Rev-responsive element was absolutely required for the expression and encapsidation of vectors containing cis-acting repressive sequences and [r] ... See full document
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Insulin-Like Growth Factor II mRNA Binding Protein 1 Associates with Gag Protein of Human Immunodeficiency Virus Type 1, and Its Overexpression Affects Virus Assembly
... recognize cis-acting RNA elements named “zipcodes” and regulate the transport, subcellular distribution, and local translation of mRNA ...zipcode-binding protein called Staufen 1 has ... See full document
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Concerted Action of Multiple cis-Acting Sequences Is Required for Rev Dependence of Late Human Immunodeficiency Virus Type 1 Gene Expression
... Late human immunodeficiency virus type 1 (HIV-1) gene expression depends on cis-acting elements and the interaction of Rev with its cognate RNA ... See full document
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The Rev protein of human immunodeficiency virus type 1 counteracts the effect of an AU-rich negative element in the human papillomavirus type 1 late 3' untranslated region.
... Human immunodeficiency virus type 1 (HIV-1) is the etio- logic agent of ...and env genes coding for structural ...and Rev, regulate gene expression and are ... See full document
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Positive and Negative Modulation of Human Immunodeficiency Virus Type 1 Rev Function by cis and trans Regulators of Viral RNA Splicing
... SR protein expression on Rev function and HIV-1 env RNA ...of viral RNA splicing and Rev function could be mod- ulated by overexpression of factors mediating ESE or ESS ... See full document
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The rev-responsive element negatively regulates human immunodeficiency virus type 1 env mRNA expression in primate cells.
... the Rev-dependent expression ob- served with the constructs described above, two other vectors, pMC120 and pMC160 D 3 9D RRE, which lack additional se- quences within the gp41 coding region of ... See full document
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The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions.
... 4966-4971 0022-538X/92/084966-06$02.00/0 Copyright X 1992, American Society for Microbiology The Matrix Protein of Human Immunodeficiency Virus Type 1 Is Required for Incorporation of Vi[r] ... See full document
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The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.
... contained strikingly lower amounts of phosphorylated MA than wild-type virions (Fig. 1A). Of note, this difference was less apparent when examining MA molecules extracted from virus producer cells (data not ... See full document
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Regulation of human immunodeficiency virus env expression by the rev gene product.
... As expected, no RNA could be detected in either the cytoplasmic or nuclear preparations from the cells transfected with DISCUSSION The data presented here demonstrate that HIV envelope p[r] ... See full document
8
The Carboxy-Terminal Region of the Human Immunodeficiency Virus Type 1 Protein Rev Has Multiple Roles in Mediating CRM1-Related Rev Functions
... truncated Rev mutant is a weaker activa- tor than the wild-type Rev ...truncated Rev mutant is fully active com- pared to wild-type Rev (13, ...mutant Rev proteins in ... See full document
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Integration is not necessary for expression of human immunodeficiency virus type 1 protein products.
... In addition, in all three cell types used in this study peripheral blood lymphocytes, Mo-T, and MT-4, infection with wild-type HIV-1 mfA virions and integrase mutants resulted in the syn[r] ... See full document
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Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression.
... PAVLAKIS1* HARRISON,' Human Retrovirus Section1 and Human Retrovirus Pathogenesis Group,2 National Cancer Institute-Frederick Cancer Research and Development Center, ABL-Basic Research P[r] ... See full document
7
Mutational analysis of cis-acting packaging signals in human immunodeficiency virus type 1 RNA.
... To determine whether sequences that we had previously demonstrated to be important for binding of HIV-1 RNA to the HIV-1 Gag polyprotein in vitro 9, 35 were necessary for packaging of RN[r] ... See full document
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Diminished Rev-Mediated Stimulation of Human Immunodeficiency Virus Type 1 Protein Synthesis Is a Hallmark of Human Astrocytes
... impaired Rev response. The only other cell types reported not to support Rev-dependent posttranscriptional regulation of HIV-1 are murine fibroblasts (57), which also do not support Tat function ... See full document
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Function of the human immunodeficiency virus types 1 and 2 Rev proteins is dependent on their ability to interact with a structured region present in env gene mRNA.
... Although the same secondary structures are required for HIV-1 and HIV-2 Rev interaction with the HIV-2 RRE, it appears that a smaller, more well-defined structure is utilized for HIV-1 i[r] ... See full document
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