[PDF] Top 20 Purinergic signalling in bone cells
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Purinergic signalling in bone cells
... calvarial bone organ ...that purinergic nerve stimulation leads to release of prostaglandins involved in the physiological regulation of gut motility, with the two stimuli forming a functional link ... See full document
267
Purinergic signalling in bone
... in bone homeostasis and accordingly several labs have investigated the role of the P2X7 receptor in bone cells, and more specifically in osteo- clast fusion and multinucleation: in vitro blockade of ... See full document
7
The role of purinergic signalling in the musculoskeletal system
... role purinergic signalling in the musculoskeletal system has increased significantly in the past twenty ...receptor-mediated signalling exerts complex, local effects on bone cell ...this ... See full document
29
Expression of P2 Purinergic Receptors in Mesenchymal Stem Cells and their Roles in Extracellular Nucleotide Regulation of Cell Functions.
... Stem cells including MSC reside in a highly specialized microenvironment termed the stem cell niche (Scadden, ...stem cells in an undifferentiated state (Mohyeldin et ...the purinergic ... See full document
37
Electromagnetic field treatment increases purinergic receptor P2X7 expression and activates its downstream Akt/GSK3β/β-catenin axis in mesenchymal stem cells under osteogenic induction
... porous bone, is a disease in which the density and quality of bone are re- ...reduced bone mass and micro-architectural degradation of bone tissue, resulting in increased bone fragility ... See full document
13
Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells
... JNK signalling and related functional outcomes in human endothelial ...endothelial cells, and employed the use of endogenous activators of P2YRs and well characterised pharmacological inhibitors, to assess ... See full document
17
Purinergic signalling during zebrafish development and the characterisation of novel fish mutants
... There are a variety of mutagenic agents that have been used to generate fish to be screened for novel phenotypes. The two main points that have to be taken into account when choosing a mutagen are the efficiency and the ... See full document
352
Purinergic signalling in mammalian skeletal muscle development and regeneration
... satellite cells, immune cells and motor ...satellite cells are activated, proliferate and ultimately fuse to repair and replace damaged muscle fibres (for review see Bischoff, 1994; Seale and ... See full document
328
Carcinoma-specific expression of P2Y11 receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells
... The second interesting finding from the present study is specific expression of the P2Y 11 receptor in human HCC tissues. A recent study has reported functional expression of the P2Y 2 receptor in hepatocytes, and its ... See full document
13
Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated signalling pathways
... Cells were washed twice with cold PBS, and then lysed with fresh RIPA containing a cocktail of protease inhibi- tors, including 1 mM PMSF, 5 mM EDTA and 1 mM phosphatase inhibitor. Cells were scraped off ... See full document
11
Adenosine Receptors Machinery and Purinergic Receptors in Rat Primary Skeletal Muscle Cells
... therefore, no effect was observed for ligands. 3) G i protein might not be expressed in skeletal muscle; a potential significant influence is that the conditions for culturing myotubes are different from those in vivo, ... See full document
16
Contribution of the Purinergic Receptor P2X7 to Development of Lung Immunopathology during Influenza Virus Infection
... of purinergic signaling through the P2X7r during virus infection has been demonstrated using different ...mononuclear cells (PBMC) from hepatitis C virus-infected patients showed that the upregulation of ... See full document
15
B cell deficiency and anaemia caused by mutations in the murine atp11c gene
... List of Figures Figure 1.1 The developmental stages of B cells in the bone marrow 7 Figure 1.2 Signalling events downstream of the IL-7R 11 Figure 1.3 Signalling events downstream of the[r] ... See full document
308
Purinergic signalling: Sensitisation of recombinant P2X receptors
... follicular cells are responsible for the triggering of, and regulation of, oocyte ...(CHO) cells and Human Embryonic Kidney (HEK) cells have been shown to have endogenous P2X? and P 2 X 4 receptors, ... See full document
281
Purinergic signalling in skin
... In this study, the distribution of P2X$ receptors within human epidermis has been shown for the first time. These receptors are also expressed in the stratum basale, but are expressed more strongly in the stratum ... See full document
306
Purinergic signalling in endocrine organs: Testis, thyroid, thymus
... Usually cells express varying numbers o f a single hormone ...single cells. Cells can respond differently to a single hormone throughout various developmental stages or after cross-talk with ... See full document
257
Purinergic signalling in the urinary tract
... slender cells in the prostate stroma, which also stain for smooth muscle myosin, confirming that they are smooth muscle ...the purinergic synergism is largely mediated by ... See full document
189
Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells
... Capan-1 cells were incubated with vesicular and non-vesicular transport ...When cells were treated with probenecid, there was a significant decrease in ATP release to 24 ± 9 nM (n = ... See full document
16
Bradykinin increases resensitization of purinergic receptor signaling in glioma cells
... [11,12]. Purinergic signaling is also believed to play an important role in the development and proliferation of glial cells under both physiological and pathological conditions, including those associated ... See full document
8
purinergic receptor regulates steroid synthesis and proliferation of ovarian luteal cells
... luteal cells remain unclear. Methods: Primary murine luteal cells were isolated and ...6 purinergic signaling regulated progesterone secretion by inhibiting the expression of CYP11A, 3β-HSD and StAR ... See full document
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