[PDF] Top 20 The relation between recombination rate and patterns of molecular evolution and variation in Drosophila melanogaster

... true variation from machine artifacts (DePristo et ...relationship between SNP call annotations and the probability that an SNP is a true genetic variant versus a sequencing or data processing artifact ... See full document

... In all cases the Cognac population showed the highest sum of ranks across loci (i.e., the fewest number of alleles, see APPENDIX B, and the lowest gene diversity, see[r] ... See full document

... on patterns of codon ...no recombination, wsHR interference causes a decrease stancy of codon bias across species, then we predict that, in bias of ⵑ60% and a decrease in diversity of 40% on average, ... See full document

... of Drosophila melanogaster, the ratio of silent DNA sequence diversity for X-linked loci to that for autosomal loci is approximately one, instead of the expected “null” value of ...mutation rate and ... See full document

... The relation between variability and recombination the pattern just described by examining the frequency rate thus seemed to provide evidence for the frequent spectrum of neutral polymorphic ... See full document

... average recombination rate in the X chromosome appears to be higher than that in the autosomes, much more so in RG than in ...average recombination rate of RG to that of RAL for each ... See full document

... in Drosophila melanogaster and its relatives, these studies have mostly focused on the small dot (fourth) chromosome, where recombination is minimal or com- pletely absent (Haddrill et ...the ... See full document

... sequence evolution was examined for three species of Drosophila, using two samples: the published sequences of eight genes from regions of the normal recombination rates and new data of the four AS-C ... See full document

... This shows that inversions sometimes maintain blocks of genes, thus counteract- ing the homogenizing effect of recombination (AQUADRO et al. African haplotypes are name[r] ... See full document

... two Drosophila lineages, higher codon bias in Drosophila yakuba, and lower bias in ...in recombination rates in the X-chromosome telomere regions between the two species, suggesting that the ... See full document

... mutation rate heterogeneity has progressed in conjunction with study of its molecu- lar structure and its associated ...substitution rate changes with specific time intervals was gradually supplemented by ... See full document

... assessed between 238 single-nucleotide and 20 indel polymorphisms spread over 11 kb of the Drosophila melanogaster Egfr locus and nine relative warp measures of wing ...in Drosophila to ... See full document

... within molecular evolution studies is to understand more about the causes of the molecular evolutionary patterns that are rec- orded within and between ...that evolution is ... See full document

... changes between the Or22 copies underlie the functional differences that we had ...differences between copies of Or22a and Or22b to enable this ...changes between these control this overall change in ... See full document

... icant variation due to ...structures between quantita- could be due to linkage disequilibrium with a linked tive characters, on which selection may act, and molecu- quantitative trait locus (QTL) that it is ... See full document

... Treatment begun at 114 or 120 hr, corresponding to a preoocytic stage, results in a significant decrease in exchange as compared to the untreated control; treatment initiate[r] ... See full document

... The establishment of these exchange preconditions must be basically a polar event and the nondisjunction of chromosome 4 in mei-9 (and by inference in recombination-defecti[r] ... See full document

... The total frequency of abdominal spots (single and twin spots combined) is higher in the flies carrying either one of the two autosomal inversions, than in the struct[r] ... See full document

... The model assumes that, in some stage or stages of development, the male recombination elements cause a particular event that does not occur i n normal males and that this event[r] ... See full document

... (2) the extent of genic variation at a locus (mean heterozygosity) within a species is not correlated with the extent of divergence (Nei's genetic distance) at that locu[r] ... See full document