[PDF] Top 20 Role of Feedback and Dynamics of a Gene Regulatory Network
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Role of Feedback and Dynamics of a Gene Regulatory Network
... the dynamics of gene expression and sugar ...of gene expression and galactose metabolism were orchestrated together and exhibited switch-like ...unknown regulatory mechanism that blocks ... See full document
132
Genetic Regulatory Circuit Dynamics: Analysis and Synthesis
... a role for quorum sensing, but show that it cannot explain most of the multi-cell-cycle delay observed here (Figure ...cell-autonomous feedback-dependent mechanism analyzed here allows deferral time to be ... See full document
92
Dynamical modelling of feedback gene regulatory networks
... We have constructed two stochastic models for the tryptophan operon system using two contemporary dominant frameworks: stochastic differential equations or the Langevin equations and the Gillespie’s stochastic ... See full document
227
Neural Differentiation Dynamics Controlled by Multiple Feedback Loop Motifs in a Comprehensive Molecular Interaction Network
... large-scale network, such as a comprehensive knowledge-integrated model of a target phenomenon, for example a whole-cell model, the variation of analyses is limited to particular kind of analysis because of the ... See full document
20
System identification of gene regulatory networks for perturbation mitigation via feedback control
... using feedback control for the mitigation of perturbations to gene regulatory networks due to disease and environmental disturbances is gaining ...relevant dynamics of the gene ... See full document
7
Regulatory networks controlling ANAC092 expression during different stress responses in Arabidopsis thaliana
... A gene-regulatory network is believed to act at the centre of the circadian rhythm in ...controlling gene expression central to circadian rhythms are ...a feedback loop composed of ... See full document
272
Chaotic expression dynamics implies pluripotency: when theory and experiment meet
... expression dynamics can show differentia- tion into multiple cell types without tuning ...cellular dynamics is most likely to generate multiple cell types, by using computer simulations of interacting cells ... See full document
11
A direct role for murine Cdx proteins in the trunk neural crest gene regulatory network
... Wnt-Cdx regulatory axis can be reiteratively used to control successive overlapping steps of early trunk NC development: in specification of the posterior neural plate border via regulation of Pax3 and Msx1 , and ... See full document
12
Laws for the dynamics of regulatory networks
... positive feedback circuits are precisely those expected for the mechanisms which ensure the two types of biological regulations, homeostatic and differentiative, ... See full document
7
A gene regulatory network for cell differentiation in Caenorhabditis elegans
... The network contained 15 ...the network represent genes that play a regulatory role ...model network contains considerably fewer nodes than the actual number of regulatory genes ... See full document
15
A Framework for Engineering Stress Resilient Plants using Genetic Feedback Control and Regulatory Network Rewiring
... of feedback control, for mitigating the effects of pathogen attack on plant gene regulatory networks, and demonstrated via simulation the ability of this approach to restore the levels of CHE, a key ... See full document
29
Transcriptional regulation by Pax3 and TGFbeta2 signaling: a potential gene regulatory network in neural crest development
... Pax3 also regulates TGFβ2 (Mayanil et al., 2006), which in turn decreases Pax3 increased Hes1 and Ngn2 promoter activity. These observations suggest that a coordinated gene regulatory network between ... See full document
12
Pitx1 directly modulates the core limb development program to implement hindlimb identity
... prominent role in patterning the skeleton and has the capacity to generate HL-like features in FL: ectopic expression of Pitx1 in the FL of mice leads to structural changes in the FL skeleton, as well as ectopic ... See full document
11
Analysis of Gene Sets Based on the Underlying Regulatory Network
... of feedback loops which are common features of cell cycle related ...the feedback is usually effective after a time delay and therefore, when time series data is used to study these networks, the cycles can ... See full document
21
Evolution of Developmental Gene Regulatory Networks in Echinoids
... variable gene ac- tivity in early development may be linked to the problem of differentiation (Brachet, ...variable gene activity theory in development (Stedman and Stedman, 1950; Mirsky, ...molecular ... See full document
183
Lessons from a gene regulatory network: echinoderm skeletogenesis provides insights into evolution, plasticity and morphogenesis
... the network is shown in ...the network depends upon maternally derived components of the canonical Wnt signaling pathway, a pathway that plays a key role in early axis specification in diverse animal ... See full document
11
Architecture and dynamics of the jasmonic acid gene regulatory network
... 351 352 Inference of regulatory interactions reveals key regulators of local JA subnetworks 353 Next, we made use of the TF DNA-binding motif information of the genes in the temporally 3[r] ... See full document
54
Research and Application of Differential Equation System in Gene Regulation Network and Metabolic Pathway
... one gene is affected by other genes, which in turn affect the expression of other ...complex regulatory network of gene ...of gene expression level, it has been widely used in the ... See full document
7
Genomic cis regulatory networks in the early Ciona intestinalis embryo
... whereas the mRNA level of one target (KH.C9.27), which was expressed in muscle at the gastrula stage (Fig. 6), was significantly increased in embryos injected with the MyoD MO. In total, the Fig. 6. Expression patterns ... See full document
11
Towards gene network estimation with structure learning
... comparison, it is categorised into one of the three categories. The control value was set as the average expression level of the gene across experiments. To discretize the data, a threshold was set to the ratio ... See full document
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