[PDF] Top 20 SELECTION FOR HIGH MUTATION RATES IN CHEMOSTATS
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SELECTION FOR HIGH MUTATION RATES IN CHEMOSTATS
... Four kinds of experiments support this conclusion: first, the growth rate constants and saturation levels are, as far as we can tell, the same for uncompeted mut+ and mutTl popu[r] ... See full document
16
Purifying Selection, Drift, and Reversible Mutation with Arbitrarily High Mutation Rates
... substitution rates for sites under purifying selection may be close to or even greater than rates at neutral sites with high b ...stitution rates to the strength of purifying ... See full document
22
Depletion of somatic mutations in splicing associated sequences in cancer genomes
... the Selection Model, that suggests increased purifying selection at exon ends (and a uni- form mutation rate across exons) and also with a model, which we refer to as the Mutation Model, which ... See full document
12
Independence of Evolutionary and Mutational Rates after Transmission of Avian Influenza Viruses to Swine
... and selection would be ex- cluded, such a resulting rate would not be a clear correlate to the mutation ...Darwinian selection, random sampling effects (5) and an increased number of rep- lication ... See full document
7
Complexities of Viral Mutation Rates
... countervailing selection for higher mutation ...higher mutation rates are increased adapt- ability and faster replicative speed ...higher mutation rate could be favored because it ... See full document
8
The causes and consequences of asexuality in Daphnia: insights into the evolution of sex
... elevated mutation rate compared to nuclear DNA, likely due to less efficient DNA repair, a more mutagenic local environment (putatively caused by oxidative radicals), and an increased number of replications per ... See full document
144
Strategy parameter variety in self adaption of mutation rates
... the selection pressure and the nature of the self-adaptation scheme in ...use. High selection pressure has the characteristic of creating multiple copies of an individual, the strategy parameters of ... See full document
8
Mendel's Accountant: a biologically realistic forward-time population genetics program
... Validating selection with equal mutational effects. Selection effects were extensively validated using: 1) equal mutational effects (all mutations have an effect of identical magnitude, specified by the ... See full document
19
Viral Mutation Rates
... shown, selection can bias mutation rate esti- ...to mutation rates is straightforward (equa- tions 5 and ...correcting selection bias when lethality or neutrality is not ...The ... See full document
16
The Influence of Hitchhiking and Deleterious Mutation Upon Asexual Mutation Rates
... of mutation rates: Another im- portant influence upon the distributions of mutation rates found in nature could be the genetic accessibility of various mutator ...ESS mutation rate ... See full document
12
Polymorphism aware species trees with advanced mutation models, bootstrap and rate heterogeneity
... balancing selection may be ...nonreversible mutation models consistent with heterogeneous mutation rates (Lie–Markov models, Woodhams et ... See full document
8
Selection Constrains High Rates of Tandem Repetitive DNA Mutation in Daphnia pulex
... from mutation, recombination, and replication slippage, combined with selection to maintain the genome ...that selection acts on the sequence motifs themselves, as they serve to bind centromere and ... See full document
14
Why Are Phenotypic Mutation Rates Much Higher Than Genotypic Mutation Rates?
... of mutation rates by natural selection has attracted the attention of evolutionary biol- ogists for many decades (S turtevant 1937), and a large number of models have been developed to understand ... See full document
10
Quantifying GC-Biased Gene Conversion in Great Ape Genomes Using Polymorphism-Aware Models
... that mutation rates from strong to weak alleles are higher, but rather similar between alleles of the same ...and selection act in great apes leads the number of substitutions to decrease on ... See full document
16
Evolution of complexity in RNA-like replicator systems
... We also have to strenuously object to the assertion, expressed on p. 7 (Authors' note: this refers to the first para- graph of the section titled "Ecological organization of the repli- cator system"), that the ... See full document
20
Automatic Generation and Execution of Mutants
... Class Mutation Operators: AMC( Access Modifier Change), IHD (Hiding Variable Deletion), IHI( Hiding Variable Insertion), IOD( Overriding Method Deletion), IOP( Overriding Method Calling Position Change), IOR( ... See full document
7
Practical Application of Optimization Techniques to Drinking Water Distribution Problems
... random mutation; NPC n point crossover; SeM selection mutation; FM flatiron mutation; CM copycat mutation; LPM list proximity mutation; SuGS subdivision growth/shrinkage; SuM ... See full document
8
The colonization of pyrethroid resistant strain from wild Anopheles sinensis, the major Asian malaria vector
... a high level of resistance to pyrethroids, indicating a very low proportion of susceptible individuals living in the natural populations, we were not surprised to find that the mortality of the progeny of the wild ... See full document
8
Semantic Mutation Testing for Multi-Agent Systems
... semantic mutation testing (SMT) into multi- agent ...semantic mutation operators ...semantic mutation operator classes for rule-based agent ...semantic mutation operators for Jason, that SMT ... See full document
18
Coordinated Changes in Mutation and Growth Rates Induced by Genome Reduction
... increased mutation rates remains ...growth rates were collected (a total of 75 data sets), and the representative genes of mutHLS, of which the mutants and/or deletions showed increased ... See full document
10
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