[PDF] Top 20 SmN: Expression and potential role in alternative mRNA splicing
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SmN: Expression and potential role in alternative mRNA splicing
... mammalian splicing have been found only in the first six bases of the 5' splice site sequences and the last two bases of the 3' splice site sequences (Treisman et ...for splicing to take place however (Reed ... See full document
186
Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing
... gene expression by RNase H–com- petent oligonucleotides targeted to the AUG codon or other sequences in mRNA is a predominant method of utilizing these compounds ...gene expression (35). Thus it ... See full document
7
Identification, mRNA Expression, and Functional Analysis of Chitin Synthase 1 Gene and Its Two Alternative Splicing Variants in Oriental Fruit Fly, Bactrocera dorsalis
... The full-length cDNA sequence of BdCHS1 was obtained from DNA fragments amplified by PCR from cDNA from the integument and from 5′ and 3′-RACE (Supplementary Material: Table S1). The full-length cDNA consisted of 5,552 ... See full document
12
SMN Deficiency in SMA: Splicing Gone Awry
... the SMN protein, which we have determined is a part of a large multi-protein complex (the SMN complex) that contains at least seven additional proteins, identified as Gemins ...The SMN complex is ... See full document
6
Alternative RNA splicing: contribution to pain and potential therapeutic strategy
... of alternative splicing relating specifically to nociceptive systems was the production of calcitonin gene-related peptide (CGRP) encoded by the calcitonin gene [1], a neuropeptide intimately associated ... See full document
12
Differential alternative splicing regulation among hepatocellular carcinoma with different risk factors
... the splicing pathway were not included, whereas in the present study, we identified an mRNA splicing path- way containing 6 ...gene expression by removing mRNA transcripts containing ... See full document
12
Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity.
... Since the mRNAs using the competing SA4a, SA4b, SA4c, and SA5 splice sites are multicistronic, potentially coding several proteins from each mRNA 15, 48, 49, we examined the effect of al[r] ... See full document
14
Patterns of alternative splicing in response to cold acclimation in fish
... the potential importance of qualitative changes in gene expression comes from studies of the phenomenon of RNA editing, in which there is enzymatic conversion of individual bases within a transcript that ... See full document
13
SKIP controls flowering time via the alternative splicing of SEF pre-mRNA in Arabidopsis
... 33]. Alternative splicing of the tobacco (Nicoti- ana tabacum) N gene contributes to the control of plant disease resistance ...gene expression 1, a cold-inducible DEAD (Asp-Glu-Ala-Asp) box RNA ... See full document
17
Alternative splicing and extra-telomeric role of telomerase reverse transcriptase isoforms in human embryonic stem cells
... crucial role in maintaining telomere ...as alternative lengthening of telomere (ALT) or ...Notably, alternative splicing of the TERT transcript to β-hTERT and its extra-nuclear localization ... See full document
148
The Function of Pre-mRNA Alternative Splicing in Mammal Spermatogenesis
... Alternative splicing coupled to nonsense- mediated mRNA decay (NMD) is an efficient strategy to regulate gene ...the potential substrates of NMD ...indispensable role of NMD in ... See full document
11
Evolution of NCoR 1 and NCoR 2 corepressor alternative mRNA splicing in placental mammals
... to alternative mRNA splicing, generating an extensive series of corepressor protein variants that are expressed at different abun- dances in different tissues, preferentially associate with different ... See full document
6
Meininger, Isabel (2017): Alternative splicing of MALT1 controls signaling and activation of CD4+ T cells. Dissertation, LMU München: Fakultät für Biologie
... regulate alternative splicing by sequence-specific pre-mRNA binding, but also by modulating the core splicing machinery (Xiao et ...of splicing events suggesting that hnRNP U acts as a ... See full document
161
Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome
... truncate mRNA expression and to generate out-of-frame products following the deletion of a critical ...of expression and splicing at the Cenpj tm1a(EUCOMM)Wtsi ...of splicing over the ... See full document
18
Differential gene expression and alternative splicing in insect immune specificity
... output of the DEXSeq analysis is available in the Additional file 2: Table S2. 615 loci displayed alternative splicing depending on the the interaction between the host genotype and the parasite genotype. ... See full document
16
Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice
... Second, alternative splicing contributes to further complexity of Shank3 isoforms and functional di- ...Alterative splicing of Shank3 is predicted to have an impact on the function of Shank3 since it ... See full document
14
Tissue specific mRNA expression profiles of GDF9, BMP15, and BMPR1B genes in prolific and non prolific goat breeds
... tissue-specific mRNA expression profiles of GDF9, BMP15, and BMPR1B genes in goats were ...The mRNA expression of the genes was detected in prolific Jining Grey goats and non-pro- lific ... See full document
7
CADM1 mRNA expression and clinicopathological significance in esophageal squamous cell carcinoma tissue.
... CADM1 mRNA expression levels were downregulated with increase in histological grading, but there was no significant difference (t = ...CADM1 mRNA in those patients with lymph node metastasis was ... See full document
9
<p>Regulation of alternative splicing in obesity-induced hypertension</p>
... the expression of genes to in fl uence obesity or hypertension will be dependent on the expression of different isoforms of the protein encoded by these ...cant role in the development of hypertension ... See full document
19
The expression and alternative splicing of alpha neurexins during Xenopus development
... neurexin expression in the tailbud embryo Tailbud embryos that are capable of simple swimming move- ments coordinated by embryonic primary neuronal circuits (Roberts and Clarke, 1982) were analysed by in situ ... See full document
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