[PDF] Top 20 A systematic review of the diagnostic accuracy of prostate specific antigen

... Methods: Medline was searched (from 01/1998 to 01/2008) and Embase (from 01/1998 to 01/ 2008), which returned 3087 citations. These were assessed by 6 reviewers, who shortlisted 54 of possible relevance. 2 reviewers ... See full document

... The systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines using 9 ...HBsAg diagnostic accuracy of rapid ... See full document

... nary antigen (UA), or direct immunofluorescence ...a diagnostic tool for LD. This systematic review assesses the diagnostic accuracy of PCR in various clinical samples with a ... See full document

... rapid antigen detection tests (RADT) are extensively used in clinical ...a systematic review and meta-analysis to evaluate the accuracy of RADTs for diagnosis of RSV infection and to determine ... See full document

... Two reviewers (TW, MDS) will independently screen the study eligibility and extract data. Screening will be a two-step process with initial title/abstract screening followed by full-text screening. Disagreements among ... See full document

... Primary study data for each physical finding was analyzed using a computer program, Meta-Test version 0.6 (J Lau, New England Medical Center, Boston 1997). The meta- analytic approach followed the recommendations of Mid- ... See full document

... survival (Gondos et al, 2008). Current UK guidelines recommend urgent referral of patients aged 40 years and older who report rectal bleeding with a change of bowel habit towards looser stools and/or increased stool ... See full document

... A systematic search of studies of diagnostic tests was performed in the following databases from their inception to the present: MEDLINE; EMBASE; Cochrane Controlled Trials Register Center (CENTRAL); and ... See full document

... of prostate diseases on Health Departments throughout the world is on the rise, as a consequence of the improved survival rate of the ...with prostate cancer being an important differential ...management. ... See full document

... of diagnostic test accuracy as they tend to overestimate diagnostic ...with prostate cancer by a urologist without having a biopsy which means not all participants in the study received the ... See full document

... sible, diagnostic data will be arranged in 2 × 2 tables to calculate the above outcome measures and pooled to pro- duce summary likelihood ratios for positive and negative test ...of diagnostic ... See full document

... This is the first systematic review to assess the effect of anti- biotics specifically in men with type IV prostatitis. In all the included studies, men treated with antibiotics exhibited a decrease in PSA; ... See full document

... on prostate cancer needle-biopsies: a ...the diagnostic accuracy of sig- nificant prostate cancer detection compared to standard transrectal ultrasound-guided biopsy: a systematic ... See full document

... Any systematic review is limited by the quality of the available studies. The most important limitation is that most studies were retrospective and did not include a control group (i.e. men with type IV ... See full document

... Our systematic review has two major drawbacks, which we would like to ...the diagnostic accuracy of available tests for ...all diagnostic tests, in- dicating that included patients with ... See full document

... adopted cutoff level of 0.15 has come under vivacious criticism from many scholars. Lujan et al. [7] in their study, in which they dismissed the idea of using PSAD cutoff level of 0.15 for detecting CAP, reported that ... See full document

... of prostate cancer, checkpoint inhibitors have demonstrated little benefit as monotherapies ...targeting specific pro- teins have demonstrated anti-tumor ...targeting prostate tumor antigens such as ... See full document

... For that, we first checked whether there were remaining core fucosylated glycoproteins other than PSA in the process of immunopurification of the serum PSA with specific antibodies against PSA. These antibodies ... See full document

... evaluating the role of PET scans in this patient population. 42-45 Evidence now indicates a role for novel imaging in the management of local disease. 19 The FALCON study, a prospective phase III trial of 85 patients ... See full document

... of prostate gland, both PSMA and PSA transcriptions are androgen-dependent ...pendent prostate cancer cell line C4-2B compared to the androgen-dependent cell line LNCaP ...advanced prostate cancer ... See full document