[PDF] Top 20 The selection-mutation-drift theory of synonymous codon usage.
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The selection-mutation-drift theory of synonymous codon usage.
... It is argued that the bias in synonymous codon usage observed in unicellular organisms is due to a balance between the forces of selection and mutation in a finite population, wi[r] ... See full document
11
In Vivo Introduction of Unpreferred Synonymous Codons Into the Drosophila Adh Gene Results in Reduced Levels of ADH Protein
... for codon bias is thought to be relatively weak ...the selection-mutation-drift (SMD) model expression efficiency of heterologous genes in cultured of codon bias predicts that ... See full document
6
Analysis of synonymous codon usage in Hepatitis A virus
... extreme codon usage bias in ...the codon usage bias in HAV, which is shown in Figure 2, indicating that the codon usage in HAV genome is influenced by the C+G content which is ... See full document
8
Selection at the Amino Acid Level Can Influence Synonymous Codon Usage: Implications for the Study of Codon Adaptation in Plastid Genes
... of selection on interplay of two forces, mutation bias and selection the evolution of a particular sequence when polymor- between synonymous codons (Li 1987; Akashi and phism data are ... See full document
12
Codon Usage Bias Covaries With Expression Breadth and the Rate of Synonymous Evolution in Humans, but This Is Not Evidence for Selection
... of selection we can predict that tRNA levels of the codon usage bias that we find in sequences in should be more highly skewed for the amino acids show- our sample when correcting for background ... See full document
9
The Effect of Mutation and Selection on Codon Adaptation in Escherichia coli Bacteriophage
... phage codon adaptation is important not only for understanding the process of translation elongation, but also for reengineering phages for medical and industrial ...of mutation and selection on ... See full document
15
The characteristics of the synonymous codon usage in hepatitis B virus and the effects of host on the virus in codon usage pattern
... natural selection from host is responsible for selection of various strains shaped by ...translation selection and compositional constraints under the mutational pressure are thought to be the major ... See full document
10
Patterns and influencing factor of synonymous codon usage in porcine circovirus
... from mutation pressure which influ- ences on codon usage pattern in PCV, the usage pattern is also influenced by other ...virus’s codon usage pattern would be subject to its host ... See full document
9
Patterns of Synonymous Codon Usage in Drosophila melanogaster Genes With Sex-Biased Expression
... of synonymous codons (codon bias) is a well-established phenomenon in Drosoph- ...of codon bias differ among genes that are differentially expressed between the sexes, with male-expressed genes ... See full document
10
FLEXIBLE SHARING IN DHT BASED P2P NETWORKS USING METADATA OF RESOURCE
... one codon, which is known as synonymous codon [1-2]. Synonymous codons are used preferentially in different organisms, with some codons used more often than others ...as codon ... See full document
6
Compare the differences of synonymous codon usage between the two species within cardiovirus
... with codon usage ...in codon usage bias for ThV (Table 3), but not for ...for codon bias of ...natural selection is the one of the main fac- tors responsible for the variation of ... See full document
8
Purifying Selection, Drift, and Reversible Mutation with Arbitrarily High Mutation Rates
... purifying selection may be close to or even greater than rates at neutral sites with high b ...purifying selection is con- sistent with the patterns described by Cutter et ...between codon ... See full document
22
Synonymous Codon Usage in Bacteria
... with codon usage statistically different from the overall codon ...and selection for optimal codons (Li, ...translational selection is effective only if the size of the population ... See full document
8
Codon bias of influenza a viruses and their hosts
... Evolutionary drift in Influenza is commonly evaluated through the study of codon ...A codon is a combina- tion of three out of the four possible nucleic bases in gene sequences: Adenine - ‘A’, ... See full document
9
Synonymous Rates at the RpII215 Gene of Drosophila: Variation Among Species and Across the Coding Region
... of synonymous substitutions detected in the ...if synonymous mutations behave as nearly ...for synonymous and nonsynonymous substitutions was detected when comparing the ...lineages. Codon ... See full document
12
X-Linked Genes Evolve Higher Codon Bias in Drosophila and Caenorhabditis
... optimal codon frequencies than their autosomal paralogs ...examine codon usage in duplicate gene pairs in ...on codon bias in an additional compar- ison, by taking advantage of the autosome-X ... See full document
11
Balancing Selection at Closely Linked, Overdominant Loci in a Finite Population
... small values of c even when ε is relatively large in abso- values of both CF and FE that are roughly comparable lute value (ε ⫽ ⫺0.04 in Table 4A). The loss of comple- to those found in the data. The simulation results ... See full document
12
Molecular epidemiology of campylobacteriosis and evolution of Campylobacter jejuni ST 474 in New Zealand : a thesis presented in partial fullfilment [sic] of the requirements for the degree of Doctor of Philosophy at Massey University, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand
... positive selection, where dS and dN denote the number of synonymous substitutions per site ( s / S ) and the number of non- synonymous substitutions per site ( n / N ) within a codon, ... See full document
399
Contrasted evolutionary constraints on secreted and non-secreted proteomes of selected Actinobacteria
... Codon usage bias affecting the selection pressure We examined whether evolutionary constraints on the genes are influenced by the codon usage ...that codon usage bias ... See full document
16
Changing Effective Population Size and the McDonald-Kreitman Test
... to synonymous variants that segregated at a variety of frequencies; he therefore inferred that most of the amino acid polymorphisms were slightly deleterious and Figure ... See full document
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