[PDF] Top 20 Transforming growth factor β signaling in uterine development and function

... TGFβ signaling in leiomyoma are largely ...TGFβ signaling in- duces molecular changes that facilitate leiomyoma forma- ...TGFβ signaling in the etiology of leiomyoma, a number of substances or drugs, ... See full document

... Transforming growth factor β (TGF β ) is important in inflammation, angiogenesis, reepithelialization and connective tissue regen- eration during wound ...TGF β signaling ... See full document

... Wing development in Drosophila is a common model system for the dissection of genetic networks and their roles during ...wing development, including patterning, cell determination, growth, ... See full document

... biological function of TRIM66 in ...and transforming growth factor-β (TGF-β) signaling pathway­related genes were enriched in TRIM66 higher expression patients, which was ... See full document

... lial growth factor, facilitation of basic fibroblast growth factor mediated capillary sprouting, inhibition of endothe- lial cell migration, and increased production of extracellular matrix, ... See full document

... functional development of the mammary gland is largely postnatal in both humans and mice (for review ...of growth is characterized by a specialized morpho- logic unit called the end-bud, which is a ... See full document

... in a Smad-independent manner, important effector pathways for tyrosine kinase receptors, including PKB/ Akt and extracellular regulated kinase (ERK) [9, 10]. TGF-β is a strong inhibitor of proliferation in ... See full document

... TGF- β in vivo, it is also important to appreciate that there are several extracellular controls on TGF-β function that can spatially and temporally regulate TGF- β action to allow context ... See full document

... A previous report has identified that alleviation of neural apoptosis can improve anti-BBB dis- ruption after subarachnoid hemorrhage [25]. Dong et al. have identified that inhibition of apoptosis signaling ... See full document

... death. Transforming growth factor- β (TGFβ) has been implicated as causative in the development of thoracic aortic aneurysms ...TGF β inhibits AAA development. ... See full document

... SMAD signaling by competitive protein–protein inter- actions either in the cytoplasm or the ...physiological function of these inhibitory SMAD proteins might be to provide a negative feedback regulation of ... See full document

... of growth factors that promote fibrosis, such as mesenchymal marker vimentin, and a-smooth muscle actin (a-SMA) ...the development of fibrosis, the mo- lecular mechanisms have not been well characterized ... See full document

... protein in many cancers, including breast, and may con- tribute to TGF-β resistance [37,80–82]. Less often, primary tumours may exhibit strong cytoplasmic p27 expression associated with poor prognosis. Cytoplasmic ... See full document

... TGF-β signaling in ...its signaling receptors [39], we analyzed TGF-β receptor expression in LX-2 cells treated with 10 ng/ml TGF-β2 in comparison to ...TGF-β signaling in HSCs ... See full document

... hepatocyte growth factor (HGF), granulocyte – macrophage colony-stimulating factor (GM-CSF), trans- forming growth factor beta (TGF- β ), and insulin-like growth ... See full document

... Nerve growth factor (NGF) is a neurotrophin that modulates ...necrosis factor (TNF)-α and interleukin (IL)-1β, in mouse and human articular chondrocytes, synovial fi- broblasts, and synovial ... See full document

... prominent alterations in dermal capillary vasculature~and the presence of dermal and epidermal T cells, monocytehacrophages, and polymorphonuclear leukocytes?.6 We have recently shown th[r] ... See full document

... whose function is relevant for Turner ...follicular development and histological examination reveals large oocytes, absent or abnormal granulosa ...and growth differentiation factor 9 (GDF9) ... See full document

... Real-time PCR was used to describe the expres- sion levels of cytokines (including EGF, FGF-β, KGF, HGF, TGF-β1, IGF-1 and IGF-2) in injured corneal tissues. Samples from both central and peripheral cornea were ... See full document

... Notch signaling can lead to the initiation of EMT by activating nuclear factor-κB (NF-κB) or altering TGF-β signaling ...Notch signaling and poor overall survival in breast cancer ... See full document