[PDF] Top 20 Virulence of La Crosse virus is under polygenic control.
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Virulence of La Crosse virus is under polygenic control.
... Second, there are sufficient differences between La Crosse virus and other members of the California serogroup in both antigenic composition 15 and protein structure 1 to allow the typin[r] ... See full document
7
Genome sequence analysis of La Crosse virus and in vitro and in vivo phenotypes
... of virulence in humans and that only those LACVs with a specific L segment sequence are isolated from humans with ...Since virus with mosquito- or human-specific L segment sequences did not differ in ... See full document
10
Characterization of La Crosse Virus RNA in Autopsied Central Nervous System Tissues
... LAC virus is distributed throughout the eastern half of the United States (5, ...LAC virus occur frequently (11); however, less than 1.5% of LAC virus infec- tions are clinically apparent (11, ...the ... See full document
5
Potential for La Crosse virus segment reassortment in nature
... Laboratory studies have demonstrated the occurrence of genetic shift (segment reassortment) in mosquitoes that have become dually infected by ingesting viruses of two different LACV genotypes, either simultaneously or ... See full document
15
LA CROSSE ENCEPHALITIS: A REVIEW
... is under-reported because the etiologic agent is often not specifically ...Disease Control and ...LAC virus infections in children ranges from 26:1 to ... See full document
9
Visualizing Production of Beta Interferon by Astrocytes and Microglia in Brain of La Crosse Virus-Infected Mice
... luciferase under the control of the IFN-  promoter and stained organ sections with luciferase-specific ...of La Crosse virus (LACV)-in- fected mouse brains that contained many infected ... See full document
8
Effects of La Crosse virus infection on the host seeking behavior and levels of two neurotransmitters in Aedes triseriatus
... the control. To determine if virus titer varied in responding and non-responding mosquitoes, 10 mosquitoes from each category were randomly selected and assayed individually from 3 different ... See full document
7
La Crosse Virus Nonstructural Protein NSs Counteracts the Effects of Short Interfering RNA
... of virus replication at a low MOI ...of virus (Fig. 2). To determine if siRNAs could clear the virus when they were delivered after virus infection and viral gene expression, we infected 293T ... See full document
11
Age-Dependent Myeloid Dendritic Cell Responses Mediate Resistance to La Crosse Virus-Induced Neurological Disease
... La Crosse virus (LACV) is the major cause of pediatric viral encephalitis in the United States; however, the mechanisms responsi- ble for age-related susceptibility in the pediatric population are ... See full document
10
Lymphocytes have a role in protection, but not in pathogenesis, during La Crosse Virus infection in mice
... preventing virus entry to the ...in control- ling virus replication in adult animals, but the impact of the adaptive immune response in preventing the develop- ment of neurological disease in these ... See full document
14
Anti-mRNAs in La Crosse bunyavirus-infected cells.
... When the primer which detects the L mRNA was extended on pellet RNA, a ladder of bands resulted, with those at positions -12 to -14 being the strongest relative to the single band at + 1[r] ... See full document
7
Borrelia burgdorferi infection surrounding La Crosse, Wis
... Lyme disease, named after the site of an epidemic of oligoarticular arthritis 31, is a multisystem infection often accompanied by a unique skin lesion, erythema migrans., Subsequent epid[r] ... See full document
5
The translational requirement for complete La Crosse virus mRNA synthesis is cell-type dependent.
... Complete S mRNA synthesis in vivo, during both primary and secondary transcription, thus requires concurrent translation in our animal cell lines.. Curi- Downloaded from http://jvi.asm.o[r] ... See full document
7
Serodiagnosis of La Crosse virus infections in humans by detection of immunoglobulin M class antibodies
... For primary serodiagnosis of LAC virus infections in humans, the MAC ELISA can be used to replace the more conventional HI and neutralization tests because it is rapid, sensitive, and le[r] ... See full document
5
Indirect fluorescent antibody technique for serological diagnosis of La Crosse (California) virus infections
... The IFA test was as sensitive as the HI and Nt tests in the detection of antibody in acute-phase specimens Table 2 of patients subsequently diagnosed by the Nt and HI test as having LAC [r] ... See full document
6
The ends of La Crosse virus genome and antigenome RNAs within nucleocapsids are base paired.
... 122 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The three La Crosse virus genomes are found as circular structures in the electron microscope, and the RNA ends of a[r] ... See full document
7
Recombination between snowhoe hare and La Crosse bunyaviruses.
... Intracellularpolypeptides induced by wildtype SSH virus, wild-type SSH/LAC/LAC virus, and eight cloned putative recombinant viruses obtained from dual mutant virus infections involving S[r] ... See full document
11
Protection from La Crosse virus encephalitis with recombinant glycoproteins: role of neutralizing anti-G1 antibodies.
... the La Crosse virus proteins with those of other members of the ...Hantaan virus G1 and G2 in either vaccinia virus or baculovirus resulted in higher titers of neutralizing antibody and ... See full document
7
An Economic and Social Analysis of La Crosse Encephalitis in North Carolina
... I would not have been able to complete this task without academic and personal support. I am thankful to Dr. Charles Apperson for providing me the opportunity to further my education and work towards a better ... See full document
183
La Crosse virus nucleocapsid protein controls its own synthesis in mosquito cells by encapsidating its mRNA.
... 5166 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Within 24 to 48 h of La Crosse virus infection of mosquito cells, >75% of the S mRNA was found to band in CsCl dens[r] ... See full document
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