and P63
Age-dependent changes of p53 and p63 immunoreactivities in the mouse hippocampus
... or p63 is removed by genetic ...that p63 +/− mice show a decreased lifespan and features of accelerated aging with decreased proliferation and enhances expressions of sen- escent markers such as ...
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Evaluation of expression of P63 and amelogenin in human tooth germ and ameloblastoma
... of p63 in odontogenic cysts and tumors such as odontogenic keratocyst, ameloblastoma, radicular cyst, dentigerous cyst and calcifying odontogenic ...cyst. P63 monoclonal antibody, clone 4A4 ( Code N 1604 ...
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Notch signaling represses p63 expression in the developing surface ectoderm
... and p63 at E10/E11, embryos were processed for immunocytochemistry using cleaved Notch1 (Val 1774-D3B8) (4147, rabbit, 1:100, Cell Signaling) and p63 (described above) ...
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Role of p63 and basal cells in the prostate
... The prostate contains two major epithelial cell types: luminal and basal epithelial cells. Both luminal and basal epithelial cells develop from the urogenital sinus epithelium (UGE), which is stratified squamous (Wang et ...
10
Original Article Diagnostic role of DOG1 and p63 immunohistochemistry in salivary gland carcinomas
... DOG1 expression in salivary tissues was found to be localized immunohistochemically mainly in salivary acini, to a lesser extent in mucinous acini and the staining diminished at the level of intercalated ducts and was ...
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STAT3, stem cells, cancer stem cells and p63
... p63 is well known for its role in epidermal development. The importance of this pro- tein during this process was established using p63 null mice. Those mice showed a complete lack of stratified squamous ...
20
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas
... factor p63, as opposed to the transcription factor OCT4, which is the preferred SOX2 binding partner in ES ...and p63 exhibit- ed overlapping genomic occupancy at a large number of loci in SCCs; however, ...
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A Study on Mucin Histochemistry and P63 Expression in Benign and Malignant Prostatic Lesions
... AND P63 EXPRESSION IN BENIGN AND MALIGNANT PROSTATIC LESIONS” is the bonafide work done by me at the Institute of Pathology, Madras Medical College under the expert guidance and supervision of ...
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The dominant-negative interplay between p53, p63 and p73: A family affair
... with p63 and p73 was increased compared to p53-WT, as previously described ...with p63/p73 isoforms [34, 77, ...with p63/p73 suggesting that tetramers of R175H interfere with p63 and ...p53, ...
16
The microRNA feedback regulation of p63 in cancer progression
... between p63 and miRNAs (Figure 3) ...of p63 via multiple components, including miRtarBase, Targetscan, ...target p63 mRNA by at least two different algorithms. Because p63 can bind to p53 ...
20
Objectives This study is aimed to assess the expression of a panel 3 IHC markers - CK5/6, p63 and TTF-
... Single MarkerSensitivity & Specificity for Squamous Cell Carcinoma v/s Adenocarcinoma Analysis of one-marker sensitivity and specificity showed that immunohistochemical markers CK5/6 and p63 were 100% ...
5
Expression of P63 and its correlation with prognosis in diffuse large B-cell lymphoma: a single center experience
... of P63 in DLBCL. In 2002, Di Como et al. [2] found a P63-positive population in non- Hodgkin’s B-cell lymphoma and normal lymph nodes and detected the expression of P63 in peripheral blood ...
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The role of P63 in cancer, stem cells and cancer stem cells
... of p63-/- mice undergoes an unusual process of non-regenerative ...hypothesis, p63 is proposed to be essential for specification and differentiation of stratified epithelial cells [74, ...hypothesis, ...
32
<p>The Expressions of Keratins and P63 in Primary Squamous Cell Carcinoma of the Thyroid Gland: An Application of Raman Spectroscopy</p>
... that p63 was abnormally expressed in thyroid cancer. 22,23 The p63 gene is located on chromosome 3q27~3q29, expresses in the basement membrane of the epithelium of different organs, and has high speci fi ...
7
Role of expression of P63 and calponin in gastro-intestinal tract carcinomas
... p63 is a member of the chromosome 3q27-29. It encodes at least six different transcripts with transactivation (TAp63) or negative effects (DNp63) on the p53 reporter genes, resulting in tumour suppressor and ...
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Chemosensitivity is controlled by p63 modification with ubiquitin like protein ISG15
... of p63 causes downregulation of cell adhesion–associated genes in mam- mary epithelial cells and keratinocytes, whereas overexpression of ΔNp63α isoforms upregulates cell adhesion molecules ...
16
Application of CD56, P63 and CK19 immunohistochemistry in the diagnosis of papillary carcinoma of the thyroid
... CD56, P63, CK19 and E- Cadherin (table ...nuclear P63 staining is accounted as positive expres- sion of ...for P63 are that shows zero nuclear staining for P63 in the lesional/neoplastic ...
12
Aberrant Cytoplasmic Expression of P63 and Prostate Cancer Mortality
... of p63 is essential for its role as a transcription ...of p63 in the cytoplasm is associated with higher lung cancer mortality ...that p63-induced apoptosis is reduced when Mdm2 exports two isoforms ...
13
Increased invasiveness and aggressiveness in breast epithelia with cytoplasmic p63 expression
... both p63 and WT-1 play significant roles in the early developmental of several organs and systems [42,43], it is possible that at the early stage of breast morphogenesis, the breasts of these patients may have ...
15
Original Article Mouse p63 variants and chondrogenesis
... as p63 variants and the endogenous control gene Gapdh for normalization of the RNA quali- ty and ...or p63 variants-specific primers (listed in Table 1) using the Bio-Rad iQ™ SYBR Green supermix and the ...
8