bone morphogenetic proteins (BMP2/4)
Bone Morphogenetic Proteins - An Update
... Bone Morphogenetic Proteins(BMPs) are a group of growth factors and cytokines known for their ability to induce the formation of bone and ...such proteins were discovered.Of these six ...
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Role of Bone Morphogenetic Proteins in Periodontics
... Bone Morphogenetic Proteins (BMPs) were acknowledged to the world when Marshall Urist implanted demineralized bone matrix intra-muscularly into the rodents and observed new bone ...
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Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: noggin, chordin and DAN
... between bone morphogenetic proteins (BMPs) and their binding proteins in bone and cartilage ...and bone differentiation in concentration-dependent ...binding proteins, ...
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Generation of optimized preparations of bone morphogenetic proteins for bone regeneration
... wide bone areas and non-healing fractures require efficient bone formation and ...regeneration. Bone morphogenetic proteins (BMPs) are signa- ling molecules that play a crucial role in ...
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Bone morphogenetic proteins in destructive and remodeling arthritis
... including bone morphogenetic proteins (BMPs) may also be of importance in arthritis ...endochondral bone formation in vivo [11] has strongly stimulated the study of their function in skeletal ...
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The expression and potential function of bone morphogenetic proteins 2 and 4 in bovine trophectoderm
... Bone morphogenetic proteins 2 and 4 also regulate trophoblast lineage development and differentiation. Trophoblast development from human embryonic stem cells is induced by BMP2 and ...
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Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension
... the bone morphogenetic protein receptor (BMPR) type II ...the bone morphogenetic proteins (BMPs), these findings suggest that BMPs play an important role in the maintenance of normal ...
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Receptor oligomerization and beyond: a case study in bone morphogenetic proteins
... In this study we investigated the binding properties of dif- ferent BMP ligands, in vitro and on whole cells, and corre- lated these properties with immediate downstream signaling events such as SMAD phosphorylation and ...
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Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis
... Inflammation and destruction are leading pathomechanisms in chronic joint diseases. In recent years, however, aspects of regeneration and homeostasis have become more and more important. Members of the TGF-β family, ...
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Temporal regulation of mRNAs for select bone morphogenetic proteins (BMP), BMP receptors and their associated SMAD proteins during bovine early embryonic development: effects of exogenous BMP2 on embryo developmental progression
... endogenous BMP2 available dur- ing in vitro maturation and embryo culture may not be limiting to embryo developmental capacity in vitro as reflected by rates of development to the blastocyst ...to BMP2 ...
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Organizing pneumonia in mice and men
... BMPs: bone morphogenetic proteins; BMPR1B: bone morphogenetic protein receptor type-1B; BO: bronchiolitis obliterans; BOOP: bronchiolitis obliterans organizing pneumonia; CCL2: C-C ...
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Malnutrition, a new inducer for arterial calcification in hemodialysis patients?
... Data are expressed as mean ± standard error (SEM). Since not each variable was normally distributed, Pearson coefficient correlation and Spearman Rank Correlation were used to assess the relationship among calcification ...
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Specific detection of clinical samples, systematic functional investigations, and transcriptome analysis reveals that splice variant MUC4/Y contributes to the malignant progression of pancreatic cancer by triggering malignancy related positive feedback loops signaling
... Importantly, we have found that EGF domain in MUC4/ Y and its interaction with ErbB2 and ErbB3 receptors trig- ger intrinsic protein–tyrosine kinase activity and further activate intracellular signaling pathways (e.g., ...
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Original Article Effect of atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor (HMG-CoA) on the prevention of osteoporosis in ovariectomized rabbits
... Our results support previous findings that ator- vastatin has advanced effects on bone forma- tion in vivo and in vitro [11, 45-47]. To our knowledge, our study for the first time con- firmed atorvastatin have ...
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Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells
... of BMP2 inhibited CRC proliferation, migra- tion, colony and spheroid formation and in vivo tumor growth, demonstrating a tumor suppressive role for ...of BMP2 expression also restored sensitivity to ...
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The role of TGF superfamily gene expression in the regulation of folliculogenesis and oogenesis in mammals: a review
... The TGFB superfamily genes act via pathways including the BMP/Smad signaling cascade. In a special type of sheep, called the Hu sheep, the effect of these signalling pathways on the high fecundity of this breed was ...
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The efficacy and safety of core decompression for the treatment of femoral head necrosis: a systematic review and meta-analysis
... insufficient bone supply and many complications in the donor site ...allogeneic bone can avoid the defects of autologous bone, and its osteogenic and osteoinduc- tive ability is also widely ...
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Paracrine effects of human amniotic epithelial cells protect against chemotherapy-induced ovarian damage
... 10 4 hUVECs were cultured in the bottom chamber in Matrigel-coated 24-well plate (Matrigel, BD Biosciences, San Jose, CA, ...10 4 hAECs were cultured in the upper ...for 4 hours to allow the ...
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Liang_unc_0153D_15763.pdf
... of bone regeneration processes has been addressed previously (Schmidt-Bleek et ...retarded bone growth and development (manuscript in preparation) in a physiological ...during bone healing in a ...
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Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor
... Quantitative Reverse Transcription polymerase chain reaction (QPCR). Following the required period of stimulation (3, 5, 7, 14, 21 days) within the bioreactor, the MSCs in collagen gels were assessed by qRT-PCR. ...
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