Cell Function
T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity
... T cell exhibits early and height- ened signaling events and probably responds sufficiently when it meets low-avidity autoantigens to which a normal T cell would not ...
9
Abnormal endothelial cell function in scleroderma and related conditions
... pulmonary vascular lesions of scleroderma-associated pulmonary hypertension, the endothelial cell phenotype does not resemble that of cytokine-activated cells. By way of contrast sE-selectin levels were raised ...
146
Proton transport and cell function
... cell function. H+ transport is involved in three broad areas of cell function: (a) maintenance and alteration of intracellular pH for initiation of specific cellular events, (b) generation of ...
7
Cell wall arabinan is essential for guard cell function
... specific cell wall polymers on the ability of stomata to open or ...internal cell turgor without reliance on cell ...the cell wall was achieved by enzy- matic digestion with well defined, ...
7
Dicer is required for Sertoli cell function and survival
... Dicer function in testis development, we crossed mice carrying a conditional Dicer allele with an AMH-Cre transgenic line, thereby inactivating Dicer in Sertoli cells around embryonic day ...Sertoli cell ...
10
Calcium sensing receptor activation increases cell cell adhesion and ß cell function
... links cell- cell contact to the actin cytoskeleton and various signalling molecules ...of cell-cell contact, connexins (Cx) oligomerise into hexameric hemichannels (connexons) connecting the ...
30
Analysis of immune cell function using in vivo cell shape analysis and tracking
... of cell, the most obvious extension of this model being combination of macrophages and neutrophils, which is technically possible with current tech- ...labelled cell population. Many such transgenically ...
13
Immunoregulatory T Cell Function in Multiple Myeloma
... B cell differentiation and immunoglobulin ...B cell differentiation assays, proliferation and polyclonal immunoglobulin secretion optimally requires T cell help and can be inhibited both by monocytes ...
12
THE RELATION BETWEEN CELL STRUCTURE AND CELL FUNCTION
... branes, the cell membrane and the nuclear membrane. Classical histology has indicated that these membranes have many of the properties of a wall and are relatively inert, except insofar [r] ...
7
Mechanisms of mesenchymal stem/stromal cell function
... induce cell protrusions de novo, some of which formed TNTs with adjacent ...the cell membrane, LST1 was shown to interact with M-Sec, myosin, and myoferlin and also to recruit RalA, promoting its ...
13
1 The Janus Face of NKT Cell Function in
... anti-inflammatory functions of different subsets of CD1d-restricted natural killer T cells during 369. Trypanosoma cruzi infection[r] ...
11
Altered NK cell function in obese healthy humans
... NK cell activity suggesting leptin as necessary for the development and activation of NK cells ...NK cell activity in diet-induced obese rats after leptin administration caused through abrogated ...
11
Endothelial Cell Function and Dysfunction in Critically Ill Children
... EC segmental differences and the homeostatic regulation of blood flow, hemostasis, permeability, and inflammation. ECs lining the arterioles are supported by layers of SMCs, whereas those in the capillary and venular ...
13
Sex Steroids and Stem Cell Function
... protective function of MSCs by increasing or decreasing cytokine and growth factor production in these cells ...stem cell-mediated protection in a Langen- dorff ...
9
Thrombospondins as matricellular modulators of cell function
... with cell-surface receptors and the conse- quent activation of signaling pathways, by altering the activity of cytokines and growth factors that serve as signaling molecules, or by affecting the protease balance ...
7
Mesenchymal stem/stromal cell function in modulating cell death
... lung injury in vivo in a mouse model [73]. Moreover, miRNA transfer via EVs produced by human MSCs alle- viated in vivo renal tubular epithelial RCD that can be apoptosis and/or necroptosis induced in vivo by glycerol or ...
12
Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells
... b cell function [36-38], but this study demonstrates that Stem Cell Educator therapy is effective both in T1D with and without residual b cell ...Stem Cell Educator therapy suggests ...
11
Signaling in the stem cell niche: regulating cell fate, function and plasticity
... stem cell and proceeding through transit-amplifying cell stages before transitioning into the terminal differentiated state – was uncovered in the embryonic and hematopoietic stem cell fields ...
11
Modulation of dendritic cell signalling and function by redox regulators
... mesangial cell proliferation which showing acute and chronic glomerulonephritis is consistent with multiple inflammatory episodes similar to that seen in systemic lupus erythematosus (SLE) (Li et ...T cell ...
224
B lymphocytes protect islet β cells in diabetes-prone NOD mice treated with imatinib
... β cell mass in ...β cell ER stress by enhancing IRE1α activity, which drives the unfolded protein response, leading to ER stress and ultimately β cell ...β cell death ...β cell stress, ...
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