chromosome conformation capture(3C)
A cautionary note on the use of chromosome conformation capture in plants
... Chromosome conformation capture (3C) in Arabidopsis To assess the reliability and robustness of the 3C tech- nique for the detection of chromatin interactions in Arabidopsis, we used this methodology ...
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Two ways to fold the genome during the cell cycle: insights obtained with chromosome conformation capture
... Both chromosome conformation capture carbon copy (5C) and Hi-C studies revealed that A- and B-compartments are themselves composed of smaller domains, referred to as topologically associating domains ...
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A multi task graph clustering approach for chromosome conformation capture data sets identifies conserved modules of chromosomal interactions
... While current clustering and dimensionality reduction techniques have provided useful insights into genome organization, there are several key issues that need to be addressed. First, unlike traditional functional ...
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Three Murine Leukemia Virus Integration Regions within 100 Kilobases Upstream of c-myb Are Proximal to the 5′ Regulatory Region of the Gene through DNA Looping
... quantitative chromosome conformation capture PCR (3C-qPCR) assay, revealed looping structures that, in tumors, al- low integrated proviral LTRs access to the 5= control region of ...
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Capture Hi C identifies a novel causal gene, IL20RA, in the pan autoimmune genetic susceptibility region 6q23
... 3C: Chromosome conformation capture; BACs: Bacterial artificial chromosomes; CeD: Celiac disease; CHi-C: Capture Hi-C; CHiCAGO: Capture HiC Analysis of Genomic Organisation; ChIP: ...
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Classifying leukemia types with chromatin conformation data
... on chromosome 7 and encodes 11 transcription factors (Figure ...the chromosome conformation capture carbon copy (5C) technology (Figure ...chromatin conformation by converting ...
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Three-dimensional genome architecture and emerging technologies: looping in disease
... 3C: Chromosome conformation capture; 3D: Three-dimensional; 4C: Circular chromosome conformation capture on chip; 4C-seq: Circular chromosome conformation ...
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Enhancer variants: evaluating functions in common disease
... (chromosome conformation capture (3C)) [61], can be ...some conformation capture), an extension of 3C, can cap- ture all regions that physically contact a site of interest, without ...
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3C and 3C-based techniques: the powerful tools for spatial genome organization deciphering
... genomic conformation were largely based on cytological techniques, such as fluorescence in situ hybridization (FISH), which allows direct evaluation of the proximity between genetic loci using ...Recently, ...
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Xist localization and function: new insights from multiple levels
... X chromosome using the circular chromosome conformation capture technique (4C), Splinter and col- leagues showed that, upon differentiation of female ESCs, the inactive X chromosome ...
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Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype
... Circularized chromosome conformation capture sequencing; C4D: The Coronary Artery Disease consortium; CAD: Coronary artery disease; CARDIoGRAM: Coronary Artery DIsease Genome wide Replication and ...
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Effects of Branching on Conformation, Crystallization, and Self Assembly of Polymers
... Within a single bottlebrush molecule, all three polymer physics concepts discussed must be considered simultaneously: solvent quality, semidilute regime, and brush condition (the latter two are shown in Figure 1.7). With ...
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Review of polytene chromosome
... Sesman et al. (2005) In this study the effects of AFB1, a mold metabolite, on third instar larval salivary gland polytene chromosomes of Drosophila melanogaster were investigated. The various chromosomal abnormalities (= ...
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53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks
... the capture of chromosome sequences that can be partial duplications of the EJ reporter or ectopic chromosomal sequences ...of chromosome rearrangement in yeast [18], we speculate that the ...
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Structure and conformation of photosynthetic pigments and related compounds Conformation analysis of chlorophyll derivatives
... 14 turn, has more dom distortion than 9, whose contribution to this mode is slightly higher than 10. 9 and 5h have almost no conformation in this mode. The structure of 5h exhibits the largest wav(x) ...
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The synthesis of a pyridine : N oxide isophthalamide rotaxane utilizing supplementary amide hydrogen bond interactions
... The isolated macrocycles were modelled first. In the case of macrocycle 1, the minimum energy structure in solution (see Fig. 5) was found to closely resemble that of the previously reported crystal structure, 14 and the ...
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N (3 Chlorophenyl)acetamide
... syn conformation observed for the ortho-chloro substituent in N-(2-chlorophenyl)acetamide, syn to both the ortho and meta chloro substituents in N-(2,3- dichlorophenyl)acetamide, and syn to the ortho chloro ...
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The synthesis of a pyridine : N oxide isophthalamide rotaxane utilizing supplementary amide hydrogen bond interactions
... individual macrocycle and thread. This suggests that although the strongest intermolecular interactions seem to occur in the syn-syn case (closely followed by the syn-anti case), there appears to be sufficient ...
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Conformation of (–) membrenone C
... Data collection: SMART Bruker, 1999; cell re®nement: SMART; data reduction: SAINT Bruker, 1999 and Xtal3.7 ADDREF and SORTRF Hall et al., 2000; programs used to solve structure: SIR97 Al[r] ...
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Characteristics of the Adeno-Associated Virus Preintegration Site in Human Chromosome 19: Open Chromatin Conformation and Transcription-Competent Environment
... Adeno-associated virus (AAV) establishes latency in infected cells by integrating into the cellular genome, with a high preference for a unique region, called AAVS1, of the human chromosome 19. The AAV proteins ...
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