Core fucosylation
Lang, Robert (2018): An LC-MS/MS-based approach for analysis of site-specific core-fucosylation of low-concentrated glycoproteins in human serum using the biomarker prostate-specific antigen (PSA) as example. Dissertation, LMU München: Medizinische Fakultät
... structures. Core-fucosylation, consisting of an α(1,6)-Fuc modification on the innermost GlcNAc residue of the N-glycan core structure, has attracted attention, because it can be linked to various ...
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Core Fucosylation of Maternal Milk N Glycan Evokes B Cell Activation by Selectively Promoting the l Fucose Metabolism of Gut Bifidobacterium spp and Lactobacillus spp
... heavily core fucosylated. The high core fucosylation level of milk protein was further demonstrated by lectin blotting with Aspergillus oryzae lectin (AOL), which preferentially recognizes ...
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Original Article Characteristics of core fucosylation changes of TGF-β1-induced pericyte tranformation in mouse lungs
... by core fucosylation [15, 16, ...by core fucosylation (Figure ...the core fucosylation modification level of PDGFR but does not influence the expression of the PDGFβR receptor ...
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FUT8 promotes breast cancer cell invasiveness by remodeling TGF β receptor core fucosylation
... Because core fucosylation may affect cell-surface protein functions including receptor signaling [14–16], we fur- ther investigated whether blocking core fucosylation of TGF-β receptors by ...
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Development of Mass Spectrometry Molecular Analysis Strategies and Chemistries for the Quantitative Measurement of Glycans in Complex Biological Systems.
... Partial separation of isomers was achieved by liquid chromatography, however, as full resolution could not be obtained, the total area under the curves were modeled. MS/MS analysis can provide limited information about ...
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High accuracy differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma by immunoglobulin G glycosylation
... IgG fucosylation and the survival of patients with gas- tric cancer [26], there was a significant decrease in IgG fucosylation of PDAC patients with the highest 25% of survival ...Increased core ...
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Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies
... of core fucose, antigen-specific IgG1 antibodies in various alloimmune and some specific infectious diseases can display low levels of core fucosylation, although wide variation between different ...
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<p>Impact of Fucosylation on Self-Assembly of Prostate and Breast Tumor Spheroids by Using Cyclo-RGDfK(TPP) Peptide and Image Object Detection</p>
... the core α -1,6-fucose expression was signi fi cantly higher than α -1,2-fucose on the cell surface of DU145 prostate cancer ...The core α - 1,6-fucose fucosylation linkages play a signi fi cant role ...
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Stage-associated differences in the serum N- and O-glycan profiles of patients with non-small cell lung cancer
... Although fucosylation is essential for normal biologi- cal functions, a change in fucosylation has been strongly implicated in tumor development and ...of core fucosyla- tion identified by AAL was ...
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Serum IgM Glycosylation Associated with Tuberculosis Infection in Mice
... of core fucosylation across disease status, the total relative abundance of fucosylated and nonfucosylated glycans was summed separately for both naive and BCG-vaccinated ...and core fucosylated ...
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Effect of Core Thickness and Core Density on Low Velocity Impact Behavior of Sandwich Panels with PU Foam Core
... Instrumented Drop tests were conducted on the sandwich specimen (Figure 3) for different impact velocities (1.401 m/sec, 2.426 m/sec, and 3.123 m/sec) on 18 possible combination of different core thickness and ...
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Assessment of Altered Fucosylation of Serum Α-1-Acid Glycoprotein in Hepatocellular Carcinoma Patients by Gold-Nanoparticle Aggregation Immunoassay
... Glycosylation is one of the most common modifications of proteins; it regulates protein-protein interactions, cell-cell recognition, adhesion, and motility. Development of disease and its progression are very often ...
9
A 16 CORE PROCESSOR WITH HYBRID INTER-CORE COMMUNICATION
... In order to satisfy performance needs single core styles were pushed to higher clock speeds, thereby the facility demand grew at a quicker rate than the frequency. This power downside was exacerbated by styles ...
12
Core Outcome Set STAndardised Protocol Items: the COS STAP Statement
... The COS-STAD (Core Outcome Set-STAndards for Development) minimum standard recommendations have been previously identified as key considerations to im- prove the methodological approach towards planning a COS ...
7
Exploring .NET Core with Microservices, ASP.NET Core, and Entity Framework Core
... matters. Core topics include deci- phering and modularizing awkward code structures, integrating and automating tests, replacing outdated build systems, and using tools like Vagrant and Ansible for infra- ...
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Difficulties in identifying Company‘s Core Competencies and Core Processes
... companies‘ core competencies Challenge often resides in getting company to understand its own core ...on core competence, logically should suggest that organization should operate as few non-revenue ...
7
Outsourcing the internal audit function with special reference to the UK public and private sectors
... Keep All Core Activities In-House and Outsource All the -19 Non-Core Activities Frequency Table for the Public Sector Keep All Core Activities In-House and Outsource All the Non-Core Act[r] ...
375
Multi Core Processors Making the Move to Quad Core and Beyond
... Multi-core processors are the future of computing. As the wealth and complexity of the data around us grows, multi-core processors will become increasingly important for helping run businesses, governments, ...
7
On the influence of a translating inner core in models of outer core convection
... inner core can be explained by a self-sustained rigid-body translation of the inner core material, resulting in melting of the solid at the leading face and a compensating crystallisation at the trailing ...
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Core business
... shallow core of ...broad core of high quality ...academic core for all pupils, and putting academics and subject experts in charge of GCSEs to ensure that the qualifications are rigorous and fit for ...
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