drug loading
Drug Loading on Microneedles
... load drug solutions on the surface of ...of drug solutions are deposited on the top of a micro- needle patch ...The drug solution will cover the entire MNP, then followed by a drying ...a drug ...
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Entrapment efficiency and drug loading of curcumin nanostructured lipid carrier (NLC) formula
... increase drug release (Sonaje et al., 2007). The drug loading was measured by dividing the amount of curcumin absorbed in the nanoparticle system by the total amount of ...a drug ...
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Novel nanocrystal-based solid dispersion with high drug loading, enhanced dissolution, and bioavailability of andrographolide
... attempt to design an NC-SD with a combination of polymers stabilizer and superdisintegrants as matrix dispersant, in order to enhance the drug loading, redispersibility, and bioavailability of drug ...
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DRUG LOADING AND RELEASE PROPERTIES OF IONEXCHANGE RESIN COMPLEXES WHICH PREPARED BY BATCH PROCESS
... model drug, were prepared using a batch method with different functional groups, ion-exchange capacity, degree of cross linking, and resin particle ...size. Drug loading efficiency, release profiles, ...
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Glucose Reduced Graphene Oxide with Excellent Biocompatibility and Photothermal Efficiency as well as Drug Loading
... In this work, we developed a novel green route to re- duce nano-GO (nGO) by adopting pure glucose as a reductant to obtain reduced nano-graphene oxide (nrGO). Prior to the reduction, nGO was prepared by a simple ...
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Drug-loading capacity and nuclear targeting of multiwalled carbon nanotubes grafted with anionic amphiphilic copolymers
... and drug-loading ...enhanced drug-loading ...hydrophobic drug with high efficiency compared to the COOH MWCNT and Hep MWCNT ...the drug was loaded onto the PGA MWCNTs through ...
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3D extrusion printing of high drug loading immediate release paracetamol tablets
... Extrusion based 3D printing of paracetamol immediate release tablets with a very high drug.. loading 80 % w/w was successfully demonstrated.[r] ...
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Tuneable drug-loading capability of chitosan hydrogels with varied network architectures
... Advanced bioactive systems with defined macroscopic properties and spatio-temporal sequestration of extracellular biomacromolecules are highly desirable for next generation therapeutics. Here, chitosan hydrogels were ...
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Tunable drug loading and release from polypeptide multilayer nanofilms
... the loading and release of small charged (positively and negatively) drug molecules could be tuned by changing the number of fi lm layers, the pH of the application environment or the pH of drug ...
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FORMULATION DEVELOPMENT OF MODEL FAST DISSOLVING ORAL FILM OF A POORLY SOLUBLE DRUG WITH IMPROVED DRUG LOADING USING MIXED SOLVENCY CONCEPT AND ITS EVALUATION
... model drug and for increasing the solubility of poorly water soluble drug (ondansetron hydrochloride dihydrate) mixed solvency concept was used in place of organic solvent, which is a novel concept to ...
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Production of Solid Lipid Nanoparticles Drug Loading and Release Mechanism
... high drug loading and entrapment efficiency, lipophilic drug with good compatibility with lipids, have often been selected to incorporate in to ...
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RETRACTED ARTICLE: Fabrication of a microfluidic device for studying the in situ drug-loading/release behavior of graphene oxide-encapsulated hydrogel beads
... of drug loading and release, 100 μg of Rig was first dissolved in 100 mL of deionized water, to which 10 μg (10GO), 25 μg (25GO) or 50 μg (50GO) of GO was ...For drug loading, 3 mL of ...
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Sauer, Anna Magdalena (2011): Live-cell imaging of drug delivery by mesoporous silica nanoparticles: Drug loading, pore sealing, cellular uptake and controlled drug release. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... nanoparticles, drug loading and intact sealing of the pores is essential to prevent degradation or premature drug ...as drug and gene delivery ...as drug carrier for the anti- cancer ...
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Comparison of generation 3 polyamidoamine dendrimer and generation 4 polypropylenimine dendrimer on drug loading, complex structure, release behavior, and cytotoxicity
... the drug in methanol. Drug solutions (40 µ L) were added into Eppendorf microtest tubes, and the solvents in the tubes were removed to obtain phenylbutazone powder ...the drug-loading ...
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Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method
... cline and nil diffusion of first oil into liquid paraffin were advantageous to restrict minocycline leakage in comparison with other aqueous solvent diffusion methods. Polymeric particles obtained by this method had the ...
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Synthesis of nucleoside boronic esters hydrophobic pro drugs: a possible route to improve hydrophilic nucleoside drug loading into polymer nanoparticles
... We have selected the use of boronic acid derivatives for this strategy due to their distinct properties of selective binding to 1,2 Cis diols which are present in the sugar ring of the nucleoside analogue (46). This ...
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<p>Integration of PEG 400 into a self-nanoemulsifying drug delivery system improves drug loading capacity and nasal mucosa permeability and prolongs the survival of rats with malignant brain tumors</p>
... higher drug loading capacity and drug solubility in water than the old formulation, which did not contain PEG ...Bdph loading capacity to up to 50% (v/v), even in formulations using Kolliphor ...
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Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations
... the drug release rate. For instance, the cumulative release of total drugs at pH 7.4 was approximately 59.9% and 36.7% after 13 days when the weight ratios of lipid/2 were 5:1 and 1:10, respectively. Therefore, we ...
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Formulation and development of fast dissolving oral film of a poorly soluble drug, frusemide with improved drug loading using mixed solvency concept and its evaluation
... improved drug loading. In the present study, poorly soluble drug, furosemide was tried to be solubilized by employing the combination of physiologically compatible water-soluble additives ...
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LAYER BY LAYER ASSEMBLY ON THE SURFACE OF NANOPARTICLE FOR CHEMOTHERAPEUTIC DRUG LOADING
... actual loading of DOX onto the PS beads is calculated based on the subtraction method that is detailed in materials and ...of drug loading efficiency based on the subtraction method was found to be ...
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