E2 PROTEINS
Papillomavirus E2 Proteins and the Host Brd4 Protein Associate with Transcriptionally Active Cellular Chromatin
... papillomavirus E2 proteins with cellular Brd4 protein is important for transcriptional regulation of viral genes and partitioning of viral ...(BPV-1) E2 binds cellular chromatin in complex with Brd4 ...
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Enhanced transcriptional activation by E2 proteins from the oncogenic human papillomaviruses.
... of E2 function. The E2 proteins are unusual transcriptional activators in at least one respect: activation apparently requires a minimum of not only two E2 binding sites (16, 24, 27, 52) but ...
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Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus.
... of E2, and also cooperative DNA binding could be observed between the two ...and E2 proteins as well as different levels of glutaraldehyde in the cross-linking ...
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The Human Papillomavirus Type 8 E2 Tethering Protein Targets the Ribosomal DNA Loci of Host Mitotic Chromosomes
... all E2 proteins tested (3, 24, ...HPV-8 E2 proteins bind to dif- ferent regions of mitotic chromosomes and that the N-terminal domain of HPV8-E2 is not required indicated that HPV-8 ...
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Activation of the grp78 andgrp94 Promoters by Hepatitis C Virus E2 Envelope Protein
... structural proteins, compris- ing the capsid (core) protein, the envelope proteins E1 and E2, and possibly p7, are present in that order at the N-terminal end of the polyprotein ...These ...
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Growth Inhibition of HeLa Cells Is a Conserved Feature of High-Risk Human Papillomavirus E8^E2C Proteins and Can Also Be Achieved by an Artificial Repressor Protein
... E8^E2C proteins of HPV16, -18, and -31 inhibit the growth of HeLa cells via induction of cell cycle arrest and ...E8^E2C proteins of HPV16 and -18 also lead to growth arrest, HeLa cells were transfected ...
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Interaction of Bovine Papillomavirus E2 Protein with Brd4 Stabilizes Its Association with Chromatin
... expressing E2, whereas about one-third of the E2 protein was associated with the chromatin/nuclear matrix frac- tion after taking into account the enrichment of proteins in the extracted ...while ...
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Cottontail Rabbit Papillomavirus E1 and E2 Proteins Mutually Influence Their Subcellular Localizations
... (PV) E2 protein is a nuclear, sequence-specific DNA- binding protein that regulates transcription and nuclear retention of viral ...genomes. E2 also interacts with the viral E1 protein to replicate the viral ...
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CK2 Phosphorylation Inactivates DNA Binding by the Papillomavirus E1 and E2 Proteins
... and E2 on DNA replication and morphological ...and E2 proteins could be altered by CK2 phosphory- ...in E2 showed a greatly increased level of replication compared to that of the ...
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Functional interactions between papillomavirus E1 and E2 proteins.
... BPV E2 protein is required for complex formation with BPV E1 and for ...mavirus E2 proteins have been divided into three separate functional domains based on structure predictions (16) and ...
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Cell Fusion Activity of Hepatitis C Virus Envelope Proteins
... HCV proteins was cocultured with various target cell lines ...and E2 proteins consistently exhibited higher fusion activity than those express- ing either of the chimeric envelope proteins and ...
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Identification of a Domain Containing B-Cell Epitopes in Hepatitis C Virus E2 Glycoprotein by Using Mouse Monoclonal Antibodies
... Figure 1A shows an example of a sensorgram obtained from SPR analyses described above. The early stage of the sensor- gram shows the saturation step by two consecutive injections of CET-4. For the sensor chip-immobilized ...
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Identification and Analysis of Papillomavirus E2 Protein Binding Sites in the Human Genome
... N294A E2 proteins and high-risk HPV18 E2 ...HPV18 E2 proteins but not by HPV11 N294A E2, which is defec- tive in sequence-specific DNA ...of E2 did not alter any cellular ...
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Association of Bovine Papillomavirus E2 Protein with Nuclear Structures In Vivo
... replication. E2 is a tran- scription factor, which interacts with multiple proteins of the transcription machinery and is able to recruit holoenzymes to promoters ...that E2 frac- tionated into ...
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Analysis of Chromatin Attachment and Partitioning Functions of Bovine Papillomavirus Type 1 E2 Protein
... wt E2 increases over the course of at least four doublings, which indicates that, in addition to nuclear reten- tion, the active partitioning has taken ...express E2 or lack MME (data not ...
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The E8^E2C Protein, a Negative Regulator of Viral Transcription and Replication, Is Required for Extrachromosomal Maintenance of Human Papillomavirus Type 31 in Keratinocytes
... and E2 proteins ...seven E2 binding sites to be present on the plasmid (33), but only four highly conserved E2 binding sites are present among genital ...
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Processing in the pestivirus E2-NS2 region: identification of proteins p7 and E2p7.
... the E2 glycoprotein is in the 53-kDa form, while E2* accounts for only a minor ...of E2 probably results from proteolytic pro- cessing which does not occur with ...
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Analysis of binary interactions between OTUB1 and E2 ubiquitin-conjugating enzymes
... The DUB bait set was generated in the Sanderson lab by Sebastian Hayes (Hayes, 2009). The ORFs were collected from various sources mainly via Human ORFeome v1.1 (Rual et al., 2004), IMAGE clones, and from the lab of Mike ...
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Both Lymantria disparNucleopolyhedrovirus Enhancin Genes Contribute to Viral Potency
... The E2 protein exhibits approximately 30% amino acid identity to the LdMNPV E1 protein as well as the enhancins from Trichoplusia ni GV, Pseudaletia unipuncta GV, Helicoverpa armigera GV, and Xestia c-nigrum ...
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Brd4-Independent Transcriptional Repression Function of the Papillomavirus E2 Proteins
... of proteins that are characterized by two bromodomains at their amino terminus and an extraterminal domain of unknown ...BET proteins are highly con- served throughout nature, including Saccharomyces ...
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