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gap-junction channels

Two Classes of Gap Junction Channels Mediate Soma-Germline Interactions Essential for Germline Proliferation and Gametogenesis in Caenorhabditis elegans

Two Classes of Gap Junction Channels Mediate Soma-Germline Interactions Essential for Germline Proliferation and Gametogenesis in Caenorhabditis elegans

... establish gap junctions with the sheath or sheath ...that gap junctions in this region of the distal arm are composed of loosely aggregated ...large gap junction foci as observed in the ...

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Engineered connexin40 variants increased docking and function of heterotypic connexin40/connexin43 gap junction channels

Engineered connexin40 variants increased docking and function of heterotypic connexin40/connexin43 gap junction channels

... of gap junction channels types has been estimated for Cx40/Cx40 and Cx43/Cx43 homotypic GJ channels ...homomeric/homotypic channels would increase to ...GJ channels of cardiac ...

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Connexins: a myriad of functions extending beyond assembly of gap junction channels

Connexins: a myriad of functions extending beyond assembly of gap junction channels

... Gap junction channels, depending on cellular needs and conditions, alternate between "closed" and "open" con- ...regulating gap junctional function, and thus increasing the ...

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Engineered Cx26 Variant Established Functional Heterotypic Cx26/Cx43 and Cx26/Cx40 Gap Junction Channels

Engineered Cx26 Variant Established Functional Heterotypic Cx26/Cx43 and Cx26/Cx40 Gap Junction Channels

... The present study is based on atomic structural information of Cx26 channel and the sequence alignment analysis between docking compatible and incompatible connexins to hypothesize that the HB-forming docking residues in ...

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Effect of transverse gap-junction channels on transverse propagation in an enlarged PSpice model of cardiac muscle

Effect of transverse gap-junction channels on transverse propagation in an enlarged PSpice model of cardiac muscle

... transverse gap junctions were positioned at the ends of each chain, so that propagation occurred in a zigzag ...one gap junction each, whereas chains B-I had two transverse junc- tions, one at each ...

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Gap-junction channels inhibit transverse propagation in cardiac muscle

Gap-junction channels inhibit transverse propagation in cardiac muscle

... This finding surprised us at first. We were expecting either that there would be no effect on transverse transmission of excitation or that transverse transfer of excitation would be enhanced. But on further refection, ...

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Continuous Time Markov Chain Models of Voltage Gating of Gap Junction Channels

Continuous Time Markov Chain Models of Voltage Gating of Gap Junction Channels

... In this study, we use CTMC, instead of DTMC, to model gating of GJ channels. The CTMC model has an advantage over DTMC, because construction of infinitesimal generator (transition rates matrix) is relatively easy, ...

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Functional Interactions between Polydnavirus and Host Cellular Innexins

Functional Interactions between Polydnavirus and Host Cellular Innexins

... in gap junction channels with properties distinct from those of Inx2 or Vnx homotypic ...intercellular channels that are sensitive to transjunctional ...form channels with voltage ...

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PKCγ knockout mouse lenses are more susceptible to oxidative stress damage

PKCγ knockout mouse lenses are more susceptible to oxidative stress damage

... epithelium, gap junctions consist of a dominant connexin 43 (Cx43) and a minor ...the gap junctions are comprised of equal amounts of Cx46 and Cx50 (Kistler et ...controls gap junctions in the lens ...

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The Interaction Between Quinine and Trimethylamine in the Formalin Test

The Interaction Between Quinine and Trimethylamine in the Formalin Test

... a gap junction channel opener and has been reported to open gap junctions as a result of intracellular alkalinization ...that gap junction openers exacerbate seizure activity ...close ...

7

Expression pattern of different gap junction connexins is related to embryo implantation

Expression pattern of different gap junction connexins is related to embryo implantation

... Int I De, IIi,,! ~o 361 367 (1996) 361 Expression pattern of different gap junction connexins is related to embryo implantation RUTH GRUMMER BERNHARD REUSS and ELKE WINTERHAGER* Institute of Anatomy,[.] ...

7

The functional implication for endothelial gap

The functional implication for endothelial gap

... Keywords: gap junction; connexin; angiogenesis; cell mechanics; cell migration; cellular stiffness 26.. 27.[r] ...

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Reduction in gap junction intercellular communication promotes glioma migration

Reduction in gap junction intercellular communication promotes glioma migration

... homocellular gap junctions in glioma migration we used short hairpin RNA to reduce endogenous Cx43 in the human glioma cell line ...blocks gap junction communication ...

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Modeling of Unsteady Flow through Junction in Rectangular Channels: Impact of Model Junction in the Downstream Channel Hydrograph

Modeling of Unsteady Flow through Junction in Rectangular Channels: Impact of Model Junction in the Downstream Channel Hydrograph

... junction obtained with the equality of the water surface (EWS) and that obtained by the energy based model (EBM): EWS junction model overestimates the peak flow and decreases the falling limb’s times of ...

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The Role of Gap Junction in Regulating Vascular Function and Its Relationship with Hypertension

The Role of Gap Junction in Regulating Vascular Function and Its Relationship with Hypertension

... the gap junctions ...the gap junctional communication of Hex cells (Hela-Cx37) which only expressed Cx37 while NO cannot inhibit the gap junctional communication of Hela-Cx40 or ...myoepithelial ...

5

Connexins: Synthesis, Post-Translational Modifications and Trafficking in Health and Disease

Connexins: Synthesis, Post-Translational Modifications and Trafficking in Health and Disease

... HeLa cells increases Cx43 expression, promotes gap junction formation and increases signalling.. 478.[r] ...

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Luteinizing hormone causes MAP kinase dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption

Luteinizing hormone causes MAP kinase dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption

... of gap junction closure, and which involves a positive stimulus rather than a reversal of the mural cell inhibition, is supported by studies of isolated cumulus- oocyte ...prevents gap ...

10

Assembly of the cochlear gap junction macromolecular complex requires connexin 26

Assembly of the cochlear gap junction macromolecular complex requires connexin 26

... Disruption of cochlear GJPs is reproduced by human cDNA clones for CX30 and CX26, with or without mutations in HeLa cells, and leads to functional differences in dye transfer depending on the resultant GJP sizes. (A–E) ...

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Effect Of Enclosed Air Gap And Empty Gap For Thermal Screens In PV Cells Isolation Inside The Hybrid Photovoltaic-Thermal Channel On A Rooftop Designed For Natural Ventilation In Bioclimatic Buildings

Effect Of Enclosed Air Gap And Empty Gap For Thermal Screens In PV Cells Isolation Inside The Hybrid Photovoltaic-Thermal Channel On A Rooftop Designed For Natural Ventilation In Bioclimatic Buildings

... convection have been analyzed numerically. As reviewed in the literature and shown by S.L. Sinha et al.[9], the results in fig.3 show that when Raleigh number is increasing for a fixed Reynolds number Re=20, the ...

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Gap junction blockers: a potential approach to attenuate morphine withdrawal symptoms

Gap junction blockers: a potential approach to attenuate morphine withdrawal symptoms

... that gap junctions play an important role in the synchronization of neuronal oscilla- tory activity that has been implicated in many cognitive processes and in the generation of epileptic discharges ...

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