Gene Regulatory Network (GRN)
Wnt6 activates endoderm in the sea urchin gene regulatory network
... In the sea urchin, entry of -catenin into the nuclei of the vegetal cells at 4th and 5th cleavages is necessary for activation of the endomesoderm gene regulatory network. Beyond that, little is ...
10
Modeling multiple time units delayed gene regulatory network using dynamic Bayesian network.
... the gene expression dataset. Some re searchers argue th at gene expression data does not contain enough information to construct gene regulatory network, especially for large ...
101
Role of Feedback and Dynamics of a Gene Regulatory Network
... galactose gene-regulatory network (GAL) in Saccharomyces cere- visiae ...galactose regulatory network is a very well analyzed eukaryotic gene circuit that provides cells with the ...
132
Learning Gene Regulatory Network from Microarrays Based on Bayesian Network
... Bayesian network for lung ...important gene in the disease of lung ...microarray gene expression data and construct clean and straightforward gene regulatory network with high ...
7
A Gene Regulatory Network Prediction Method using Particle Swarm Optimization and Genetic Algorithm
... as gene selections and prediction of gene regulatory networks (GRNs) from microarray ...of gene selection is to select the group of genes which are most significant, while the problem of ...
6
Lessons from a gene regulatory network: echinoderm skeletogenesis provides insights into evolution, plasticity and morphogenesis
... micromere-PMC GRN consists of approximately 70 genes (a schematic view of the network is shown in ...this GRN (Fig. 4). It was shown previously that activation of the network depends upon ...
11
Gene regulatory networks and developmental plasticity in the early sea urchin embryo: alternative deployment of the skeletogenic gene regulatory network
... transcriptional gene regulatory networks (GRNs) (Davidson et ...(PMC) GRN, which underlies the development of the embryonic ...micromere-PMC GRN is  -catenin, a maternally supplied protein ...
11
Single cell transcriptomics unveils gene regulatory network plasticity
... a gene expressed ap- proximately 14 times higher in male than in female pa- tients, irrespectively of the ...same gene appears also upregulated in diabetes (p < ...addition, gene-level vari- ...
20
Cis-regulatory analysis of the sea urchin delta gene : validating the architecture of the gene regulatory network model for micromere lineage specification
... the regulatory functions predicted by the GRN ...in regulatory tandem, here pmar1 and hesC, and non-localized activators to generate a highly localized spatial pattern of gene ...similar ...
174
Research and Application of Differential Equation System in Gene Regulation Network and Metabolic Pathway
... determine gene function, and analyze and predict protein ...a network structure with complex regulatory relationships, namely Gene Regulatory Network ...
7
A gene regulatory network for cell differentiation in Caenorhabditis elegans
... of regulatory proteins that determine its pattern of gene activation are divided between the daughter cells, so each will gener- ally have a similar pattern of gene expression to its ...of ...
15
Inferring Drosophila gap gene regulatory network: pattern analysis of simulated gene expression profiles and stability analysis
... The long-term dynamics of the circuits should show if the model is able to predict the disappearance of the gap gene domains, and provide information about the asymptotic stability of the model and potentially ...
10
Architecture and dynamics of the jasmonic acid gene regulatory network
... 351 352 Inference of regulatory interactions reveals key regulators of local JA subnetworks 353 Next, we made use of the TF DNA-binding motif information of the genes in the temporally 3[r] ...
54
Analysis of the PC algorithm as a tool for the inference of gene regulatory networks: evaluation of the performance, modification and application to selected case studies.
... characterized Gene Regulatory Network, called Local Gene Network (LGN) in the ...expansion gene list which reports as well an estimate of their ...corresponding gene ...
160
Towards gene network estimation with structure learning
... of gene expression data that were successfully used in cancer research and drug discovery ...of gene expression data has spurred research in gene clustering, gene classification, gene ...
5
Regulatory networks controlling ANAC092 expression during different stress responses in Arabidopsis thaliana
... A gene-regulatory network is believed to act at the centre of the circadian rhythm in ...controlling gene expression central to circadian rhythms are ...of gene tran- scription during a ...
272
Identification of differentially expressed circRNAs and a novel hsa_circ_0000144 that promote tumor growth in gastric cancer
... target gene prediction and prognosis of miRNAs We obtained the miRNAs targeting hsa_circ_0000144 in the circinteractome database (https ://circi ntera ctome ...
9
Dynamical Analysis of Regulatory Interactions in the Gap Gene System of Drosophila melanogaster
... The gene circuit modeling framework: The gene circuit step can be found at ...the gene circuit model are blastoderm nuclei de- nary nuclear masks were constructed by edge detection, and noted by the ...
18
Geometric control of ciliated band regulatory states in the sea urchin embryo
... Fig. 5. Repressor-defined CB gene expression boundaries. (A) GFP expression from the onecut reporter construct in response to Gsc transcription factor binding site (TFBS) mutation. Endogenous onecut expression ...
9
The role of <em>MAPT</em> gene in Chinese dementia patients: a P301L pedigree study and brief literature review
... Background and purpose: Frontotemporal dementia (FTD) is the second most common presenile dementia characterized by behavioral changes and language impairment. The diag- nosis of FTD relies heavily on neuroimaging, and ...
7