Hydrophilic Floating Matrix Tablets
FORMULATION AND INVITRO EVALUATION OF NIFEDIPINE EFFERVESCENT FLOATING MATRIX TABLETS BY USING HYDROPHILIC POLYMERS
... effervescent floating matrix tablets of nifedipine by using hydrophilic polymers such as Gum Cyamopsis, Xanthan gum and Sodium alginate as retarding ...
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Formulation and Devolopment of Floating Matrix Tablets of Lamivudine.
... lodged at the pyloric sphincter. As dosage form coming in contact with gastric fluid, the polymer imbibes water and swells. The extensive swelling of this polymer is a result of the presence of physical-chemical ...
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FORMULATION AND EVALUATION OF CIMETIDINE FLOATING MATRIX TABLETS
... cimetidine floating matrix tablets. Gastric floating drug delivery systems (GFDDS) offer numerous advantages over other gastric retention ...gastric floating drug ...the matrix ...
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Design, Evaluation and Study of Effect of Hydrophilic Polymers on Release Rate of Antiulcer Floating Tablets
... signiÞ cantly with the type of matrix former. The release rate could effectively be modiÞ ed by varying the ‘‘matrix- forming polymer/low density polymer’’ ratio, the tablet geometry (radius), the type of ...
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Formulation and Evaluation of Gastroretentive Floating Matrix Tablets of Perindopril Erbumine.
... 8. Sumit R.Rathi et al., developed a single unit gastro retentive DDS of Famotidine due to its shorter half life. The results indicated sodium alginate could be successfully used to modify release rates in ...
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FORMULATION AND EVALUATION OF FLOATING MINI MATRIX TABLETS OF THIAMINE MONONITRATE
... research Floating mini matrix tablets of Thiamine mono nitrate were successfully prepared with hydrophilic polymers like HPMC K 4 M, HPMC K 15 M and HPMC K 100 M with 5% sodium bicarbonate by ...
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FORMULATION DEVELOPMENT, OPTIMIZATION AND EVALUATION OF FAMOTIDINE FLOATING MATRIX TABLETS
... good floating time and minimum floating lag ...the hydrophilic matrices leads to increase in volume of dosage form resulting in lowering of density and dosage form starts to ...
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FORMULATION AND EVALUATION FLOATING DRUG DELIVERY MATRIX TABLETS OF PRAMIPEXOLE DIHYDROCHLORIDE
... the hydrophilic gel network. Immediate release dosage form of pramipexole using thrice a dai- ly, once a day FDDS form offer patients a more convenient and alternative. Patient compliance with single daily dosing ...
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FORMULATION AND EVALUATION OF GASTRO RETENTIVE EFFERVESCENT FLOATING MATRIX TABLETS OF CEPHALEXIN
... the floating formulations containing HPMC K4M (F1-F3) showed the drug release in controlled manner without changing their physical integrity in dissolution medium Formulations F1- F3 retarded the drug release as a ...
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DEVELOPMENT AND IN VITRO EVALUATION OF SUSTAINED RELEASE FLOATING MATRIX TABLETS OF METFORMIN HYDROCHLORIDE
... ABSTRACT Floating matrix tablets of metformin hydrochloride were developed and evaluated for increase bioavailability by increasing gastric residence time and sustained release of drug on the upper ...
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Self correcting monolithic floating matrix tablets of dipyridamole: Influence of formulation variables
... Gastric emptying of dosage forms is an extremely The attainment of high gel viscosity, maintenance of variable process and ability to prolong and control the constant gel layer or synchronous erosion/dissolution in a ...
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FORMULATION DESIGN AND IN VITRO EVALUATION OF ZOLMITRIPTAN GASTRORETENSIVE FLOATING MATRIX TABLETS FOR MANAGEMENT OF MIGRAINE
... Zolmitriptan floating matrix tablet were successfully ...of floating tablet of Zolmitriptan. The floating drug delivery was a promising approach to achieve a prolongation of gastric residence ...
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Effervescent floating tablets of metformin HCl developed by melt granulation. Part I: Effect of hydrophilic polymer on biopharmaceutical properties
... Except tablets obtained from F5, all the formulations with HPMC K15M and HPMC K100M corresponding respectively to F6-F7-F8 and F9-F10-F11-F12 were shown fast flotation time and total buoyancy time more than 24 ...
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Formulation and Evaluation of Cefixime Floating Matrix Tablets
... The present research work Cefixime Controlled Gas Powered System (CGPS) are retained for longer period oftime in the stomach. The bioavailability of cefixime is around 40-50 %. The gas powered tablets of Cefixime ...
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FORMULATION AND EVALUATION OF FLOATING MATRIX TABLETS OF CIPROFLOXACIN
... retention floating drug delivery is of particular interest, for drugs which, act locally in the stomach, primarily absorbed in the stomach or upper intestine, poorly soluble at alkaline pH, have a narrow window of ...
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FORMULATION AND EVALUATION OF CONTROLLED RELEASE FLOATING TABLETS OF CEFIXIME USING HYDROPHILIC POLYMERS
... Cefixime, floating tablets, controlled release, hydrophilic polymers INTRODUCTION Almost in every developing country, infectious diseases are more common, among them bacteria are most responsible ...
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Formulation and Evaluation of Floating Matrix Tablets of Sacubitril and Valsartan
... manner. Floating drug delivery system or hydrodynamically 5,6 balanced systems has been reported for prolonging the residence time of drug delivery system in a particular region of the gastrointestinal tract, were ...
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Formulation and Evaluation of Floating Matrix Tablets of Drotaverine Hydrochloride
... prepared matrix tablets were yellowish in color having smooth ...Compressed tablets that lose less than 1 % of their weight are generally considered ...
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Formulation and invitro evaluation of floating matrix tablets of mitiglinide
... Tablets containing 10mg of mitiglinide calcium dihydrate (MTG) were made by direct compression technique [6-8]. Using the ingredients and their quantities mentioned in table 1. The required quantity of drug, cross ...
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APPLICATION OF CENTRAL COMPOSITE DESIGN FOR OPTIMIZATION OF EFFERVESCENT FLOATING TABLETS USING HYDROPHILIC POLYMERS
... of floating tablet containing CT as a drug candidate, which would remain in stomach or upper part of GIT for a prolonged period of time, therefore, the maximum drug release is maintained at desired ...gastric ...
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