Korsmeyer- Peppas
Pseudo zwitterionic microvesicles for sustained urea release
... Department of Chemistry, Hazara University, Mansehra, Pakistan (Received 22 August, revised 11 December, accepted 13 December 2019) Abstract: Zwitterionic microvesicles formed by catanionic system, based on sodium ...
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Vol 2, No 3 (2010)
... and Korsmeyer-Peppas model), it is seen that all the formulations predominantly follow Higuchi model as the R 2 values are near to ...the Korsmeyer-Peppas model, Fickian/Diffusion controlled ...
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FORMULATION AND IN-VITRO EVALUATION OF EFFERVESCENT FLOATING MATRIX TABLETS OF NIZATIDINE USING NATURAL AND SEMI SYNTHETIC POLYMERS
... The dissolution data was fitted into different data models and based on the correlation coefficient (R) values the best fit model was determined. Batches F1, F2 and F3 followed Higuchi-matrix release kinetics. Batch F6 ...
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DESIGN AND DEVELOPMENT OF ENALAPRIL MALEATE MATRIX TABLET EMPLOYING NATURAL AND SYNTHETIC POLYMERS
... In this study controlled release matrix tablet of enalapril maleate was prepared by wet granulation technique using guar gum, karaya gum and xanthan gum polymers as retardant. It was found that increase in the ...
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Observation of the release of aspirin from gelatin sodium alginate polymeric implant
... Implantation technology is currently the most utilized route for studying sustained drug release potential. Present investigation explores the scope of sustaining the release of drug by using Gelatin-Sodium Alginate ...
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Development and Evaluation of Gastroretentive Controlled Release Polymeric Suspensions Containing Ciprofloxacin and Carbopol Polymers
... Since the qualitative and quantitative changes in a formulation may alter drug release and in vivo performance, several bio-studies are usually carried out. In this regard, the use of In vitro drug dissolution data to ...
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FORMULATION AND EVALUATION OF ORAL TIO2 NANOCARRIERS OF IM-ATINIB MESYLATE
... Various models were tested for kinetics of drug release. To analyze the mechanism of the drug release rate kinetics of the dosage form, the obtained data were fitted into Zero order, First order, Higuchi and ...
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Formulation and In-Vitro Evaluation of Sustained Release Matrix Tablets of Gliclazide
... The release rate of gliclazide from matrix tablets was determined using United States Pharmacopoeia dissolution testing apparatus I (Basket method; Veego Scientific VDA-8DR, Mumbai, India). The dissolution test was ...
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A NEW MATHEMATIC METHOD FOR CALCULATION OF PEPPASSAHLIN MODEL CONSTANTS AND INTERPRET THE RESULTS IN RELATION TO ZERO ORDER, HIGUCHI, KROSMEYER PEPPAS MODELS AND MICROCAPSULE STRUCTURE IMAGE
... of Korsmeyer-Peppas to be used in Peppas-Sahlin model [31] ...of Korsmeyer-Peppas equation to be equal the m value of Peppas-Sahlin ...
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FORMULATION AND EVALUATION OF GASTRORETANTIVE FLOATING TABLET USING EUDRAGIT RSPO WITH NATURAL POLYMERS
... The best fitting model for all formulation was calculated. The plain polymer batches F1- F3, the best fitted models was found to be Higuchi release. The batch F4-F9 batches followed Korsmeyer peppas model ...
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THE Formulation and Characterization of Transdermal Patch of Candesartan Celexitil
... of Korsmeyer- Peppas model shows a combination of diffusion and dissolution mechanism indicating the drug release from the formulation was controlled by more than one ...
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IN VITRO AND KINETIC STUDIES OF IMMEDIATE RELEASE SORAFINAB TOSYLATE FILM COATED TABLETS
... Sorafenib tosylate release from tablets was immediate and for a period of 30min and these formulations was found suitable immediate release formulations. It was observed that the increasing the concentration of ...
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... To analyze the mechanism of the drug release rate kinetics of the dosage form, the obtained data were fitted into zero- order, first order, Higuchi, and Korsmeyer-Peppas release [r] ...
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Design and Optimization of Capecitabine Proniosomes
... 3.1.5. In vitro drug release and release kinetics: The obtained in vitro release data for both optimized capecitabine niosome and data was fitted to various release kinetic models. The correlation coefficients (R 2 ) ...
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FORMULATION AND EVALUATION OF KARAYA GUM MICROSPHERES OF CROMOLYN SODIUM: TREATMENT OF ULCERATIVE COLITIS
... per korsmeyer-peppas model was found to be between ...the korsmeyer-peppas model which might be due to relaxation of the polymer matrix, followed by the diffusion matrix (Table ...
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Calculation of predominant drug release mechanism using Peppas-Sahlin model (substitution method): A linear regression approach
... respectively. The highest values of R 2 and adjusted R 2 were indicates that the drug release data was good linearity with Korsmeyer-Peppas equation. The drug release mechanism from tablet matrices ...
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APPLICATION OF QUALITY BY DESIGN (QBD) IN FORMULATION DEVELOPMENT OF IMMEDIATE AND EXTENDED RELEASE BILAYERED TABLETS OF DEXTROMETHORPHAN AS A MODEL DRUGMohd. Nadeem1, M. Suresh Babu1DOWNLOAD/VIEW
... The in vitro release data obtained from Formulations was fitted to kinetic models such as zero order, first order, Higuchi and Korsmeyer-Peppas models to explore the release mechanism. The data obtained ...
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FORMULATION EVALUATION AND OPTIMIZATION OF METFORMIN HCl MATRIX TABLET USING NATURAL POLYMER
... Hence, the drug release rate is proportional to the reciprocal of the square root of time Korsmeyer Peppas Equations: KorsmeyerPeppas equation used to determine the mechanism of drug rel[r] ...
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DEVELOPMENT AND IN VITRO EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF SALBUTAMOL SULPHATE USING METHOCEL K100M CR POLYMER
... In the present study, an attempt has been made to evaluate the effect of hydrophilic polymers on the release profile of drug from matrix system. Salbutamol sulphate, an anti-asthmatic agent, was used as a model drug to ...
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<p>Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review</p>
... 27 , 30 Schulz et al presented a sensor with an ideal pH range for the application, as they achieved suf fi cient sensitivity within the pH range of 7.4 to 7.0, while Liechty and Peppas i[r] ...
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