Metabolic Modeling
Advances in metabolic modeling of oleaginous microalgae
... constraint-based modeling of photosynthetic microorganisms over the last two ...decades. Metabolic modeling has been proven critical for our understanding of complex metabolism in ...ductivity. ...
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Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance
... silico metabolic modeling has emerged as a powerful approach for analyzing complex microbial communities by integrating genome-scale reconstructions of single- species metabolism within mathematical ...
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Metabolic Responses to Polymyxin Treatment in Acinetobacter baumannii ATCC 19606: Integrating Transcriptomics and Metabolomics with Genome-Scale Metabolic Modeling
... genome-scale metabolic modeling with multiomics data to elucidate the mechanisms of cellular responses to colistin treatment in ...genome-scale metabolic model, iATCC19606, was constructed for strain ...
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Genome-Scale Metabolic Modeling with Protein Expressions of Normal and Cancerous Colorectal Tissues for Oncogene Inference
... genome-scale metabolic models (GSMMs) of several organisms, including ...by metabolic dysregulation ...of metabolic processes within a cell to be curated using knowledge of cellular functions from ...
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In silico identification of metabolic engineering strategies for improved lipid production in Yarrowia lipolytica by genome-scale metabolic modeling
... showed similar growth curves to that of the wild-type (Fig. 4a). This result was expected to a certain extent because growth defective mutants were removed from the beginning of our computational pipeline (see “Mate- ...
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Metabolic Modeling of Streptococcus mutans Reveals Complex Nutrient Requirements of an Oral Pathogen
... ABSTRACT Streptococcus mutans is a Gram-positive bacterium that thrives under acidic conditions and is a primary cause of tooth decay (dental caries). To better un- derstand the metabolism of S. mutans on a systematic ...
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A framework for application of metabolic modeling in yeast to predict the effects of nsSNV in human orthologs
... In our previous paper [11] we used the SNVDis Tool [12], part of the High-performance Integrated Virtual Environment (HIVE) tools suite (accessed at hive.bio- chemistry.gwu.edu) [13] to identify the entire set of 559 ...
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From Network Analysis to Functional Metabolic Modeling of the Human Gut Microbiota
... The metabolic interactions between distinct microbial organisms can be modeled by combining the COBRA approach with individual-based modeling ...COBRA modeling to study the metabolism of single cells ...
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Metabolic modeling of synthesis gas fermentation in bubble column reactors
... Spatiotemporal modeling of microbial metabolism Steady-state [16] and dynamic [17–20] flux balance ana- lysis techniques based on genome-scale metabolic re- constructions have become standard tools for ...
12
Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor
... predicted metabolic flux is not necessarily expected; expression levels can show little correlation to protein levels, enzyme activity and metabolic flux for many reasons ...
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Machine Learning Reveals Missing Edges and Putative Interaction Mechanisms in Microbial Ecosystem Networks
... balance metabolic modeling ...that metabolic models may not capture the full biochemical details of the real system they approximate, and they do not incorporate any of the nonmetabolic processes ...
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MICOM: Metagenome-Scale Modeling To Infer Metabolic Interactions in the Gut Microbiota
... (54). Metabolic modeling incorporates a rich knowledge base from genomics and biochemistry and is a valuable resource for adding value to existing sequencing data ...genome-scale metabolic models, ...
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Disrupted flow sensing impairs hydrodynamic performance and increases the metabolic cost of swimming in the yellowtail kingfish, Seriola lalandi
... The lateral line of fish is made up of two submodalities, canal neuromasts and superficial neuromasts (Sns). The canal neuromasts respond less to steady currents and low-frequency flows, and are better suited to encode ...
12
Current status and future perspectives of kinetic modeling for the cell metabolism with incorporation of the metabolic regulation mechanism
... Among intracellular metabolites, α-keto acid such as αKG turns to be a master regulator for catabolite regula- tion and co-ordination of different regulations [139]. Namely, when favored carbon source such as glucose was ...
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The 3d fcrm modeling in miles per gallon of cars
... c-regression modeling (FcRM) are widely used in order to fit switching regression ...FcRM modeling was carried ...FcRM modeling were ...FcRM modeling with lower MSE to be the better model and ...
6
A Proposed Systemic Modeling Software for Jujube Fruit Cracking
... systemic modeling approach that help to understand the functions of external and internal factors are one of the solutions to the successful management of jujube fruit ...Mathematical modeling of these ...
9
Ontology-based metabolic pathway prediction using saccharomyces cerevisiae data from genbank, ecocyc and kegg
... Nowadays, metabolic pathway prediction is the focus of numerous drug discovery researches and is central to the stage of many biopharmaceutical and genomic ...the metabolic pathways in which potential ...
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How much methodology ror explains the rain errors in caibarién, cuba
... The information in a data series is important when projecting the future, but: what happens when the modeling series is a white noise?, therefore there is no information in previous steps allowing to model towards ...
5
Mechanics and energetics of load carriage during human walking
... There are also metabolic costs other than for moving the COM. One example is a cost for moving the legs back and forth relative to the body. That cost may be associated more with activating muscle than with ...
9
Association of metabolic and genetic heterogeneity in head and neck squamous cell carcinoma with prognostic implications: integration of FDG PET and genomic analysis
... peak), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) are the conventional metabolic or metabolic-volumetric parameters which are the most extensively studied in the previous studies ...
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