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microfluidic platform

3D-Printed Microfluidic Platform Enabling Bacterial Preconcentration and DNA Purification for Molecular Detection of Pathogens in Blood

3D-Printed Microfluidic Platform Enabling Bacterial Preconcentration and DNA Purification for Molecular Detection of Pathogens in Blood

... 3D-printed microfluidic platform that enables bacterial preconcentration and genomic DNA (gDNA) purification for improving the molecular detection of target pathogens in blood ...3D-printed ...

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Cell Segmentation and Tracking in Microfluidic Platform

Cell Segmentation and Tracking in Microfluidic Platform

... In this research, we have concentrated on trajectory extraction based on image segmentation and data association in order to provide an economic and complete solution for rapid microfluidic cell migration ...

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End-to-end automated microfluidic platform for synthetic biology: from design to functional analysis

End-to-end automated microfluidic platform for synthetic biology: from design to functional analysis

... To demonstrate an automated microbial product screen- ing assay using our microfluidics platform, we grew E. coli DH1 harboring plasmids pBbA5c-MevTsa-MKco- PMK and pTrc99A-NudB-PMD [25], induced the pro- duction ...

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Drug loaded supramolecular gels prepared in a microfluidic platform: distinctive rheology and delivery through controlled far from equilibrium mixing

Drug loaded supramolecular gels prepared in a microfluidic platform: distinctive rheology and delivery through controlled far from equilibrium mixing

... The ability of the drug-loaded gels to release the incorporated compound was studied in materials with the highest ibuprofen sodium salt content. Both, the gel prepared with mixing in the micro fl uidic platform ( ...

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Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform

Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform

... A microfluidic system for 3D cell culture was developed and used by Montanez-Sauri et ...stratified platform that is in- corporated in a microtiter plate format that is fully compatible and easy to handle ...

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A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling

A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling

... the platform to be used in different microscope ...the microfluidic device for single cell measurement and a 96-well plate for bulk sample measurement can be found in the supplementary pages (Figure ...

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A microfluidic platform for the characterisation of CNS active compounds

A microfluidic platform for the characterisation of CNS active compounds

... for the pharmacological profiling of CNS active compounds. Furthermore, our miniaturised system shows for the first time, repeatable assessment of induced network synaptic activity in addition to pharmacological ...

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Development of a passive liquid valve (PLV) utilizing a pressure equilibrium phenomenon on the centrifugal microfluidic platform

Development of a passive liquid valve (PLV) utilizing a pressure equilibrium phenomenon on the centrifugal microfluidic platform

... In our previous work, we presented an active wax valve to control the burst frequency by applying a vacuum and/or compression effect on the source and destination chamber respectively [19]. In this work, we propose an ...

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Microphysiological systems and low-cost microfluidic platform with analytics

Microphysiological systems and low-cost microfluidic platform with analytics

... Our groups have focused on developing increasingly authentic functional tissue constructs to incorporate into a multi-tissue platform based on a PBPK model. While there are signifi cant challenges in constructing ...

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Development of a myocardial infarction
model by the design of a miniaturized
3D culture platform

Development of a myocardial infarction model by the design of a miniaturized 3D culture platform

... Currently the leading cause of death in the western world is cardiovascular disease (CVD) and in the future the amount of people suffering from CVD is only projected to rise. However high-throughput disease models are ...

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Miniaturised liquid chromatography

Miniaturised liquid chromatography

... However, the trend towards miniaturisation makes the overall scale of miniaturised LC smaller and lighter. For example, in 2015, our research group reported a portable modular medium pressure capillary LC system 41 . ...

107

The role of microfluidics in protein formulations with pre-programmed functional characteristics

The role of microfluidics in protein formulations with pre-programmed functional characteristics

... potential platform to advance biofabrication of particle- and fiber/tube-based protein formu- ...of microfluidic- based formulation to preclinical and clinical application is still a ...that ...

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Microfluidic systems for biosensing

Microfluidic systems for biosensing

... capillary microfluidic platform for rapid and accurate sensing of biomarkers in clinical diagnostics and point-of-care ...a microfluidic system for whole blood handling capabilities and test and data ...

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OpenDrop ELISA: Surface Development for Digital Microfluidic ELISA Testing

OpenDrop ELISA: Surface Development for Digital Microfluidic ELISA Testing

... digital microfluidic platform upon which an enzyme-linked immunosorbent assay (ELISA) could be run, indicated for clinicians and educators in low-resource ...our platform must be at least 85% of that ...

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Immobilization of pH sensitive CdTe Quantum Dots in a Poly(acrylate) Hydrogel for Microfluidic Applications

Immobilization of pH sensitive CdTe Quantum Dots in a Poly(acrylate) Hydrogel for Microfluidic Applications

... active microfluidic elements is highly demanded since this will serve as an interface with current electronic semiconductor technologies and at the same time will enable the collection of information about the ...

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Jackson_unc_0153D_15750.pdf

Jackson_unc_0153D_15750.pdf

... Figure 2.1 (Left) Schematics of the first generation, high-throughput CTC selection device showing: (A) A scaled AutoCAD diagram of the sinusoid capture channels with brightfield optical micrographs; (B) the integrated ...

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A portable automatic endpoint detection system for amplicons of loop mediated isothermal amplification on microfluidic compact disk platform

A portable automatic endpoint detection system for amplicons of loop mediated isothermal amplification on microfluidic compact disk platform

... Abstract: In recent years, many improvements have been made in foodborne pathogen detection methods to reduce the impact of food contamination. Several rapid methods have been developed with biosensor devices to improve ...

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Validation of a fully integrated platform and disposable microfluidic chips enabling parallel purification of genome segments for assembly

Validation of a fully integrated platform and disposable microfluidic chips enabling parallel purification of genome segments for assembly

... been demonstrated for synthetic biology applications. Zhou and colleagues demonstrated the synthesis and assembly of multiple DNA sequences in a microfluidic picoarray (Zhou et al. 2004). Kong et al demonstrated a ...

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Design and validation of a microfluidic device for controlled cell stimulation

Design and validation of a microfluidic device for controlled cell stimulation

... of microfluidic technologies provides the opportunity to establish a highly controlled environment in which to study cell signaling, and more precisely control the stimulation of ...

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Chitosan Films for Microfluidic Studies of Single Bacteria and Perspectives for Antibiotic Susceptibility Testing

Chitosan Films for Microfluidic Studies of Single Bacteria and Perspectives for Antibiotic Susceptibility Testing

... Chitosan Films for Microfluidic Studies of Single Bacteria and Perspectives for Antibiotic Susceptibility Testing Chitosan Films for Microfluidic Studies of Single Bacteria and Perspectives for Antibi[.] ...

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