multiple sclerosis brain lesions
MR spectroscopy in the evaluation of enhancing lesions in the brain in multiple sclerosis
... Davie et al (22) recently reported the results of a serial MR spectroscopic study of eight pa- tients with large, acute MS plaques. All the spectra obtained from these acute lesions showed two distinct broad ...
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Combined Magnetization Transfer and Proton Spectroscopic Imaging in the Assessment of Pathologic Brain Lesions in Multiple Sclerosis
... T2-weighted lesions that are classi- fied as equivalent, the presence of T2-weighted le- sions in relatively silent brain regions that do not have a significant impact on EDSS, and the nonlin- ear and ...
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Intraobserver and interobserver variability in schemes for estimating volume of brain lesions on MR images in multiple sclerosis
... in multiple sclerosis (MS) (1, ...small lesions and of lesions located in or near the cerebral cortex, as a consequence of better spatial resolution or image ...MS lesions have been ...
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A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression
... were blinded to clinical information, conducted T2W-le- sion segmentation on T2W images using semi-automatic thresholding contour software with an interactive digital analysis program (AMIRA V.3.1.1; Mercury Computer ...
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Double Inversion Recovery Brain Imaging at 3T: Diagnostic Value in the Detection of Multiple Sclerosis Lesions
... the lesions, the NAWM, NAGM, and ...between lesions and the NAWM were per- formed separately in the infratentorial, periventricular, juxtacortical, and deep white matter ...
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The evolution of multiple sclerosis lesions on serial MR
... older lesions, with pe- ripheral inflammatory activity, rather could be ascribed to secondary capillary hyperemia and/or ...in multiple sclerosis plaques (15) and is also supported by dynamic MR ...
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Juxtacortical Lesions and Cortical Thinning in Multiple Sclerosis
... Visual inspection of JL probability maps overlaid onto the cortical change maps of the 2 hemispheres showed no overlapping in either patients with CIS or those with RRMS. A more detailed subanalysis of this aspect ...
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Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
... of lesions that were segmented as CSF, especially the low lesion volume, limited the impact of WML voxels on the overall CSF tissue distribution of original ...
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An Automated Statistical Technique for Counting Distinct Multiple Sclerosis Lesions
... smaller) lesions rather than fewer (and larger) ...of lesions nor the amount of tissue damage alone captures all rele- vant clinical information and instead suggests that they should be considered ...the ...
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Identification of Chronic Active Multiple Sclerosis Lesions on 3T MRI
... ● 2D high-resolution gradient recalled-echo providing T2* and phase contrasts (TR ⫽ 1300 ms; TE ⫽ 32 ms; 29 axial slices; flip angle ⫽ 50°; acquisition time ⫽ 8 minutes 36 seconds; in-plane resolution ⫽ 0.2 ⫻ 0.2 mm; ...
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Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
... MS lesions but were absent from chronic silent ...acute lesions, immunoreactivity for TNF in endothelial cells was noted at the lesion ...disease brain tissues but was present at lower levels in ...
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Antibody facilitation of multiple sclerosis like lesions in a nonhuman primate
... Furthermore, in the presence of encephalitogenic (e.g., disease-inducing) T cells, the fully demyelinated lesion is reconstructed by systemic administration of IgG purified from whole myelin-, or MOG-immunized animals, ...
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Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages
... the brain of MS patients, in particular within lesions (21, 24, 28), and the expression of these retroviruses correlated with disease progres- sion (29, ...
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Predictive Value of Lesions for Relapses in Relapsing remitting Multiple Sclerosis
... Following the protocol for this clinical trial, patients under- went MR imaging at baseline (time of entry into the trial) and then at monthly intervals thereafter during the initial year of the trial. All MR imaging was ...
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Characterization of White Matter Lesions in Multiple Sclerosis and Traumatic Brain Injury as Revealed by Magnetization Transfer Contour Plots
... within lesions with detectable halos seen in patients with MS are presented in Table ...of lesions without ob- vious halos (Table ...both lesions (black 5 ...
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Brain Metabolite Profiles of T1 Hypointense Lesions in Relapsing Remitting Multiple Sclerosis
... persistent lesions were studied, only those that also presented on T2- weighted MR images obtained at least 3 months earlier were chosen, as suggested by Barkhof et al ...only lesions with contrast ratios ...
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Brain atrophy in Multiple Sclerosis
... of multiple mechanisms, and these mechanisms may not be constant over time in individuals and ...and lesions at various stages are responsible of composite of (transient) volume-gaining (edema by ...
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Experimental autoimmune encephalomyelitis in the common marmoset: a translationally relevant model for the cause and course of multiple sclerosis
... horizontal brain slices from a T2-weighted image (middle) and a postcontrast (triple dose Gadolinium-DTPA; bottom) with the position of corresponding lesions ...the brain was removed and fixated in ...
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Segmentation of MS lesions using entropy based EM algorithm and Markov random fields
... MS lesions in fluid attenuated inver- sion recovery (FLAIR) Magnetic Resonance (MR) ...and Multiple Sclerosis le- ...probability, brain tissues are classified using bayesian ...segmented ...
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Neuroimaging and Cartography: Mapping Brain Tumors
... active lesions and form a major imaging marker for determining response to therapy or efficacy of new drugs; much activity is taking place that is not nec- essarily defined by enhancement ...enhancing ...
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