Non-coding
Long non-coding RNA ENST00000457645 reverses cisplatin resistance in CP70 ovarian cancer cells.
... Ovarian cancer is one of the most common gynecologic malignant tumors. Previous epidemiological studies have indicated that approximately 200,000 new cases are diagnosed every year worldwide, and the associated mortality ...
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cncRNAs : Bi functional RNAs with protein coding and non coding functions
... of non-coding to protein coding transcripts has been proposed to increase with the complexity of organisms and approximately 95% of human transcripts are thought to be non-coding RNAs ...
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Human evolution: the non-coding revolution
... human-specific non-coding elements with traits that make our species ...human-specific non-coding mutations are becoming less ...connect non-coding elements to traits and may ...
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Original Article Long non-coding RNA H19 promotes colorectal cancer metastasis via negative modulation of miR-148b
... Long non-coding RNAs (lncRNAs) are newly discovered RNAs which make up 80% of non- coding RNAs, which have been linked in every stage of cell life, including cell proliferation, ...
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The Unexpected Existence of Coding and Non Coding Fragments along the Eukaryotic Gene
... alternate coding and uncoding regions (Figure 4(A), top right): methylation did not significantly involve the coding regions but involved the non-coding ones, complementary to parts of ...
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DNA watermarks in non coding regulatory sequences
... that coding regions can be used to encrypt information into living organisms by using the DNA-Crypt ...a non- coding DNA sequence, either the function of a resulting functional RNA molecule or a ...
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Databases and resources for human small non-coding RNAs
... small non-coding RNAs (sRNAs), which were named micro-RNAs ...nucleotide-long, non- coding RNAs that have emerged as key players in post-transcriptional gene ...short non-coding ...
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Effects of miRNA-143 and the non-coding RNA MALAT1 on the pathogenesis and metastasis of HeLa cells.
... in non-small cell lung cancer. As a long non-coding RNA, it is expressed in various tumors and tissues, and may affect proliferation, apoptosis, invasion, metastasis, and drug resistance of tumors ...
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Novel classes of non coding RNAs and cancer
... Long non-coding RNAs (lncRNAs) are the broadest class encompassed all non-protein-coding RNA species with length more than 200 nucleotides, however, frequently ranging up to 100 ...
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Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy
... conserved non-coding sequences [4]. Examination of these conserved non-coding sequences in five addi- tional mammalian species demonstrated that these ele- ments are frequently conserved in ...
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The functional role of long non-coding RNAs and epigenetics
... Long non-coding RNAs (lncRNAs) are mole- cules longer than 2 kb in length with a coding potential of less than 100 amino acids, or non-protein coding tran- scripts with the length of ...
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Clinical significance of long non-coding RNA HOTTIP in early-stage non-small-cell lung cancer
... Up to 70% of our genome is transcribed into non-coding RNAs (ncRNAs) that do not serve as tem- plates for proteins. These ncRNAs are subdivided into two major groups: small ncRNAs (< 200 nt) and long ...
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Expression and clinical significance of long non coding RNA HNF1A AS1 in human gastric cancer
... Long non-coding RNAs (lncRNAs) are non-coding RNAs greater than 200 nucleotides [4]. These RNAs do not encode proteins and are the main components of the human transcriptome [5]. Emerging ...
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Identification of long non-coding RNAs biomarkers for early diagnosis of myocardial infarction from the dysregulated coding- non-coding co-expression network
... Long non-coding RNAs (lncRNAs) have recently been shown as novel promising diagnostic or prognostic biomarkers for various cancers. However, lncRNA expression patterns and their predictive value in early ...
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Encoding activities of non-coding RNAs
... How novel peptides contribute to normal development and disease will open up new avenues for this field. It is well known that cancer develops by accumulation of driver mutations. Many such mutations occur in ...
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Non-coding RNAs in cardiac regeneration
... heart. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs, miRs) and long non-coding RNAs (lncRNAs), are functional RNA molecules without a protein coding function that have been ...
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MYC regulates the non-coding transcriptome
... the non-coding ...for coding transcripts, and MYC typically binds within 1 kb of the ...for coding genes where 6,911 of 10,382 (67%) have MYC present at the ...
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Non-Coding RNAs in Bacteria
... Knowledge about the post-transcriptional regulation that ncRNAs exert on a given target mRNA related to its position and matched in ncRNA: mRNA, and which sRNA class being worked on. There are different classes of sRNAs ...
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The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology
... Among all successful efforts in applying semantic tech- nologies in the biomedical domain, the Open Biological and Biomedical Ontologies (OBO) Library [8] is of spe- cial importance in that it has served as an umbrella ...
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Androgen responsive intronic non-coding RNAs
... androgen-responsive non- coding intronic RNAs, we used a custom-built spotted cDNA microarray enriched in intronic transcribed sequences and a prostate cancer cell line (LNCaP) cul- tured in the presence of ...
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