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Preimplantation development

Histone variant H3 3 maintains a decondensed chromatin state essential for mouse preimplantation development

Histone variant H3 3 maintains a decondensed chromatin state essential for mouse preimplantation development

... reprogramming (Loppin et al., 2005), gastrulation (Szenker et al., 2012; Lim et al., 2013), neural crest lineage commitment (Cox et al., 2012) or meiosis (Sakai et al., 2009). Although in some of these studies H3.3 has ...

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Preimplantation development of manipulated mouse zygotes fused with the second polar bodies: a cytogenetic study

Preimplantation development of manipulated mouse zygotes fused with the second polar bodies: a cytogenetic study

... Original Arlie/,' Preimplantation development of manipulated mouse zygotes fused with the second polar bodies a cytogenetic study SERGEI v EVSIKOV and ALEXEI V EVSIKOV Institute of Molecular Biology a[.] ...

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Requirement of the MAP kinase signaling pathways for mouse preimplantation development

Requirement of the MAP kinase signaling pathways for mouse preimplantation development

... We then examined whether p38 and JNK are activated during mouse preimplantation development. Activation of p38 α can be assessed by using anti-phospho-specific p38 α antibody. Indirect immunofluorescence ...

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Selective loss of imprinting in the placenta following preimplantation development in culture

Selective loss of imprinting in the placenta following preimplantation development in culture

... after preimplantation culture (Table ...of preimplantation development in culture on Xist expression was determined for males ...during preimplantation development or was corrected as ...

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Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development

Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development

... during preimplantation development, with POU2F1 having a clearly early maternal expression pattern, thus overlapping with the expression of transcripts carrying its binding site in their ...

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A shift from kinesin 5 dependent metaphase spindle function during preimplantation development in mouse

A shift from kinesin 5 dependent metaphase spindle function during preimplantation development in mouse

... Although the mechanism of the transition has not been directly examined here, its timing would appear inconsistent with a number of otherwise appealing hypotheses. The kinesin 5 dependence of the first three mitotic ...

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Life giving caspases: revealing new roles during mouse embryo preimplantation development

Life giving caspases: revealing new roles during mouse embryo preimplantation development

... mouse preimplantation development as a model to evaluate the existence of non- lethal caspase ...have preimplantation lethal ...mouse preimplantation development and proposes a model in ...

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The Developmental and Adaptive role of Mitogen Activated Protein Kinase Pathways During Preimplantation Development

The Developmental and Adaptive role of Mitogen Activated Protein Kinase Pathways During Preimplantation Development

... The preimplantation period of development represents the highest interval of embryonic loss throughout ...regulating preimplantation embryonic responses to stress and that govern ...of ...

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Distribution of p53 binding protein 1 (53BP1) and phosphorylated H2A X during mouse preimplantation development in the absence of DNA damage

Distribution of p53 binding protein 1 (53BP1) and phosphorylated H2A X during mouse preimplantation development in the absence of DNA damage

... the preimplantation mammalian embryo undergo several rounds of fast cell ...of development where cell division is of primary importance, has not been fully ...the preimplantation mouse ...throughout ...

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Cytoskeleton organization during oogenesis, fertilization and preimplantation development of the mouse

Cytoskeleton organization during oogenesis, fertilization and preimplantation development of the mouse

... Inl I De\' BioI ]~ 117 137 (191)0) 127 Cytoskeleton organization during oogenesis, fertiliza tion and preimplantation development of the mouse BERNARD MARO*, JACEK KUBIAK', CATHERINE GUETH, HENRI DE P[.] ...

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Role Of Maternal Sin3a In Reprogramming Gene Expression During Mouse Preimplantation Development

Role Of Maternal Sin3a In Reprogramming Gene Expression During Mouse Preimplantation Development

... recruitment of maternal Sin3a mRNA impairs the expression of a subset of zygotically and non-zygotically activated genes during the establishment of the transcriptionally repressive state that is superimposed on ZGA. ...

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Requirement for ERK MAP kinase in mouse preimplantation development

Requirement for ERK MAP kinase in mouse preimplantation development

... Our microarray experiments have identified a set of cell cycle- related genes whose expression levels are increased or decreased by the inhibition of the ERK pathway (Table 1). These genes would be good candidates for ...

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Mitochondrial Genotype Segregation During Preimplantation Development in Mouse Heteroplasmic Embryos

Mitochondrial Genotype Segregation During Preimplantation Development in Mouse Heteroplasmic Embryos

... Zygotes containing both mtDNA genotypes were obtained from females derived from a persistent heteroplasmic lineage originated by the continuous mating of a founder heteroplasmic female o[r] ...

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Ginseng Extract Treatment Influences on Preimplantation Development in Vitro, and Pregnancy and Post-Partum Development in the Mouse

Ginseng Extract Treatment Influences on Preimplantation Development in Vitro, and Pregnancy and Post-Partum Development in the Mouse

... the preimplantation embryos were directly exposed to the ginseng extract in culture, whereas concentrations of ginseng directly affecting embryos in vivo are unknown due to uncertainties regarding ginseng compound ...

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Sperm borne miRNAs and endo siRNAs are important for fertilization and preimplantation embryonic development

Sperm borne miRNAs and endo siRNAs are important for fertilization and preimplantation embryonic development

... Differential effects were observed between supplementation experiments using total versus small sperm RNA fractions, for example, WT sperm total RNA appears to be more efficient than small RNAs in rescuing developmental ...

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Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development

Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development

... The two-cell delay and disruption of ZGA are consistent with a maternal effect because maternally derived products are presumed to regulate these early processes. We have yet to determine whether TRC expression in ...

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Lineage specification in the mouse preimplantation embryo

Lineage specification in the mouse preimplantation embryo

... in preimplantation embryo development The recent analyses of human embryos, and embryos from other mammals, have highlighted similarities and possible species-dependent differences in preimplantation ...

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Maternal control of early mouse development

Maternal control of early mouse development

... After remodeling, the embryonic genome becomes accessible to activation by transcription factors. Heat shock factor 1 (HSF1), a master regulator of stress-inducible genes, is highly expressed in mouse oocytes. Although ...

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Fatty acid amide hydrolase deficiency limits early pregnancy events

Fatty acid amide hydrolase deficiency limits early pregnancy events

... embryo development in vivo (Figure 3, D and E, and Figure 4D), supporting the hypothesis that regulated anandamide signaling is critical to normal preimplantation ...normal development of embryos, ...

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Constitutive PtdIns(3,4,5)P3 synthesis promotes the
development and survival of early mammalian embryos

Constitutive PtdIns(3,4,5)P3 synthesis promotes the development and survival of early mammalian embryos

... mammalian development consists of a complex series of events by which the fertilized egg develops into a blastocyst capable of implanting in the ...Interestingly, preimplantation development can be ...

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