protein interaction network
Construction of Protein Protein Interaction Network Using Community Molecular Detection
... The number of proteins continues grow. Machine learning is a subfield of computer science that includes the study of systems that can learn from data, rather than follow only explicitly programmed instructions. Some of ...
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Protein Function Prediction from Protein Interaction Network Using Clustering and Sequence of Amino Acid
... a network-flow based algorithm that exploits the underlying structure of protein interaction maps in order to predict protein ...molecular interaction networks has made possible new ...
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Systematic analysis of protein interaction network associated with azoospermia
... first protein-protein interaction network related to azoospermia and analyze the complex effects of the related genes ...Human Protein Reference Database and Cytoscape, we created a ...
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Predicting Disease-Related Proteins Based on Clique Backbone in Protein-Protein Interaction Network
... tein-protein interaction network is a topological module and possesses inherently biological sig- ...a protein-protein inter- action ...in protein networks, extending cliques and ...
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Function and evolution of genes in the human protein interaction network
... the protein interaction network gene duplication is the explanation for network ...connected protein is duplicated the duplicate will also have all the same connections ...their ...
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IN SILICO ANALYSIS OF PROTEIN-PROTEIN INTERACTION NETWORK OF HUTCHINSON GILFORD PROGERIA SYNDROME
... of protein interaction network in the cell would be the key to understand how complex processes, lead to ...diseases. Protein-protein interaction network (PPIN) analysis ...
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Using Protein-Protein Interaction Network to Prioritize Drug Targets for Malaria
... literature, interaction between organisms based on ...score interaction indicates that the interaction is supported by various types of ...A protein protein interaction ...
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Predicting the Fission Yeast Protein Interaction Network
... a network of protein interactions in fission yeast from databases (including the ones mapped from budding yeast); (2) the filtered subset of this known network used as our positive training set (two ...
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Evolutionary rate and duplicability in the Arabidopsis thaliana protein protein interaction network
... the protein–protein interaction network has been put forward as a determinant factor of the evolutionary rate and duplicability of their encoding ...the network are more evolutionarily ...
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Using Protein-Protein Interaction Network to Prioritize Drug Targets for Malaria
... Malaria is caused by the parasites of genus Plasmodium. Among five parasite species known to cause malaria in humans, P. falciparum and P. vivax are responsible for the majority of malaria cases. Malaria turns out to be ...
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Protein-Protein Interaction Network Alignment
... for protein- protein pairs, it uses the tensor product between ...the protein-protein order to improve the signature product, then it normalizes the signature product to compensate for ...
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FunPred-1: Protein function prediction from a protein interaction network using neighborhood analysis
... Spirin and Mirny [14] use a graph clustering approach where they detect densely connected modules within themselves and modules that are sparsely connected with the rest of the network based on super paramagnetic ...
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RETRACTED ARTICLE: Analysis of protein-protein interaction network and functional modules on primary osteoporosis
... receptor-related protein 5 (LRP5) effects the development of primary osteoporosis by altering bone mineral density ...morphogenetic protein-2 and bone-related proteins ...
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Fitting a geometric graph to a protein-protein interaction network
... In this section, we outline the main ideas behind the algorithm and show how we propose to evaluate its accuracy. Our task is to embed proteins into R 2 , R 3 or R 4 given the PPI network. Rather than Euclidean ...
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Construction and analysis of protein-protein interaction network associated with human sperm-egg interaction
... Male factor problems, mainly defined by abnormal semen analysis, are the single most conventionally diagnosed reason of infertility. In vitro fertilization (IVF) is implemented for men with no sperm dysfunction. ...
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RETRACTED ARTICLE: Establishing an osteosarcoma associated protein-protein interaction network to explore the pathogenesis of osteosarcoma
... Compared to the control samples, the expressions of 42 and 341 genes were altered in non-metastatic OS were analyzed in duplicate), and 11 samples for metastatic patients (10 of which were analyzed in duplicate). ...
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PROTEIN INTERACTION NETWORK AND DRUG DISCOVERY
... with protein Interleukine-6 displays, stable interaction at the interacting sites of one of the standard drug molecules as ...by interaction among the protein residues in complex, indicate ...
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Protein Function Prediction Using Neighbor Counting with Dynamic Threshold from Protein-Protein Interaction Network
... As like [16], we have also filtered out proteins that are annotated either by electronic means or have ambiguity in the evidence used to annotate the proteins. We have included only those proteins annotated with ...
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A Meta-Heuristic Approach to Predict Protein-Protein Interaction Network
... The receiver operating curves (ROCs) for different PPI prediction algorithms for interactions obtained from BioGrid database is plotted in Fig. 5(a). ROCs are a useful technique for examining the efficacy of a prediction ...
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De novo deletions and duplications of 17q25.3 cause susceptibility to cardiovascular malformations
... the protein-interaction network communicability of each candidate gene to the training genes normalized to the typ- ical communicability of each gene to the background using the InWeb Protein ...
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