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severe aplastic anemia (SAA)

Original Article Ex-vivo expansion and function identification of CD4 CD25 CD127 dim regulatory T cells in severe aplastic anemia

Original Article Ex-vivo expansion and function identification of CD4 CD25 CD127 dim regulatory T cells in severe aplastic anemia

... Acquired severe aplastic anemia (SAA) is a rare disease characterized by severe pancytopenia and bone marrow ...in SAA [3, ...

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Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

... Aplastic anemia (AA) is a rare but potentially fatal dis- order characterized by hypocellular bone marrow and ...pancytopenia. Severe aplastic anemia (SAA) is a life- threatening ...

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Value of transfusion independence in severe aplastic anemia from patients’ perspectives – a discrete choice experiment

Value of transfusion independence in severe aplastic anemia from patients’ perspectives – a discrete choice experiment

... in SAA because of advances in hematopoietic stem cell transplantation (HSCT), pharmacotherapy, and supportive care in recent decades ...of aplastic anemia, allogeneic HSCT from a matched sib- ling ...

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Original Article Activation profile of intracellular mitogen-activated protein kinases in CD8+ T lymphocytes of patients with severe aplastic anemia

Original Article Activation profile of intracellular mitogen-activated protein kinases in CD8+ T lymphocytes of patients with severe aplastic anemia

... Severe aplastic anemia (SAA) is a bone marrow failure syndrome characterized by bone marrow aplasia and severe peripheral blood pancyto- ...in SAA become activated have not been ...

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Who is the best haploidentical donor for acquired severe aplastic anemia? Experience from a multicenter study

Who is the best haploidentical donor for acquired severe aplastic anemia? Experience from a multicenter study

... for SAA remains undefined. A few studies on HLA-identical HSCT for aplastic anemia have shown that male recipients of transplants from female grafts showed decreased survival compared with other ...

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Original Article Abnormal immunomodulatory ability on memory T cells in humans with severe aplastic anemia

Original Article Abnormal immunomodulatory ability on memory T cells in humans with severe aplastic anemia

... Abstract: Severe aplastic anemia (SAA) is a bone marrow failure disease induced by hyperfunctional autoimmunic Th1 ...in SAA patients before and after immunosuppressive therapy (IST) to ...

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Original Article Abnormal quantity and function of Th17 cells in patients with severe aplastic anemia combined with infection

Original Article Abnormal quantity and function of Th17 cells in patients with severe aplastic anemia combined with infection

... Abstract: Severe aplastic anemia (SAA) is a hematologic disease characterized by peripheral pancytopenia with bone marrow ...with SAA who had severe infections, as compared with ...

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Original Article Abnormality of lymphotoxin α in CD8+ T cells of patients with severe aplastic anemia

Original Article Abnormality of lymphotoxin α in CD8+ T cells of patients with severe aplastic anemia

... Severe aplastic anemia (SAA) is a serious dis- ease that features bone marrow failure with high mortality ...rates. SAA is recognized as an autoimmune ...

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Original Article Combined treatment of sequential intensive immunosuppressive therapy and hematopoietic growth factors in patients with severe aplastic anemia: long-term outcome of hematopoietic recovery response

Original Article Combined treatment of sequential intensive immunosuppressive therapy and hematopoietic growth factors in patients with severe aplastic anemia: long-term outcome of hematopoietic recovery response

... Severe aplastic anemia (SAA) is a severe bone marrow hematopoietic failure associated with T-lymphocytes dysfunction [1, ...in SAA, the early death rate of SAA has fallen ...

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Budget Impact Of Eltrombopag As First-Line Treatment For Severe Aplastic Anemia In The United States

<p>Budget Impact Of Eltrombopag As First-Line Treatment For Severe Aplastic Anemia In The United States</p>

... Background: Severe aplastic anemia (SAA) is a rare autoimmune condition resulting in low blood cell counts across ...treating SAA with eltrombopag-based therapy from a US private ...

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Clinical evaluation of haploidentical hematopoietic combined with human umbilical cord-derived mesenchymal stem cells in severe aplastic anemia

Clinical evaluation of haploidentical hematopoietic combined with human umbilical cord-derived mesenchymal stem cells in severe aplastic anemia

... with SAA (14 males and 10 females) who underwent cotransplantation of human UC-MSCs and HSCs from June 2010 to August ...with SAA or very severe aplastic anemia (VSAA) were defined ...

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Recent Developments in Aplastic Anemia Therapy

Recent Developments in Aplastic Anemia Therapy

... with severe or very severe aplastic anemia (SAA) died 1 to 2 years after diagnosis due to fatal infections and/or hemorrhagic ...

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Hepatitis Associated Aplastic Anemia: A review

Hepatitis Associated Aplastic Anemia: A review

... induced aplastic anemia improves by the administration of retroviral therapy ...the aplastic anemic secondary to hepatitis B virus infection and remission occurs from the severe ...

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Management of aplastic anemia in a woman during pregnancy: a case report

Management of aplastic anemia in a woman during pregnancy: a case report

... very severe aplastic anemia died after intensive supportive and immunosuppressive treatment with methylprednisolon and CsA during and after ...

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Fanconi’s Anemia—Rare Aplastic Anemia at Ten Year Old Boy in Mogadishu Somalia: Case Report

Fanconi’s Anemia—Rare Aplastic Anemia at Ten Year Old Boy in Mogadishu Somalia: Case Report

... The most common anomaly is hyperpigmentation of the trunk, neck, and intertriginous areas, as well as café-au-lait spots and vitiligo, alone or in combination. Most patients have short stature. Growth failure may be ...

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Dyskeratosis Congenita: Two Examples of This Multisystem Disorder

Dyskeratosis Congenita: Two Examples of This Multisystem Disorder

... Fanconi’s anemia and dyskeratosis congenita share a number of features: short stature, pigmen- tary skin changes, aplastic anemia, predisposition to malignancy, and variable immunologic [r] ...

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Bone marrow angiogenesis and microvessel density in patients with aplastic anemia

Bone marrow angiogenesis and microvessel density in patients with aplastic anemia

... (NsAA), severe (sAA) and very severe (VsAA) based on the degree of the peripheral blood cytopenia and classified on the basis of camitta et al criteria taking into account the bone marrow ...

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Case Report Severe hepatitis-associated aplastic anemia following cytomegalovirus infection in an adult: a case report and literature review

Case Report Severe hepatitis-associated aplastic anemia following cytomegalovirus infection in an adult: a case report and literature review

... Currently, bone marrow transplantation (BMT) and IST are the main therapeutic strategies for severe HAA [13]. Allogeneic BMT is first-line therapy for HAA for its high cure rate (70%-90%) [14]. However, BMT cannot ...

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An Analysis of Efficacy of Androgenic Steroids in patients with Acquired Aplastic Anemia.

An Analysis of Efficacy of Androgenic Steroids in patients with Acquired Aplastic Anemia.

... in Aplastic Anemia : Structure and function of Telomeres and Related Structures: Telomeres are DNA-protein complexes at the ends of chromosomes that protect the chromosomes from degradation and aberrant ...

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AN EVALUATION OF CHLORAMPHENICOL THERAPY IN TYPHOID FEVER IN CHILDREN

AN EVALUATION OF CHLORAMPHENICOL THERAPY IN TYPHOID FEVER IN CHILDREN

... A., Fatal aplastic anemia associated with chloram- phenicol therapy: Report of 2 cases, J.A.M.A. K., and others, Fatal aplastic anemia following chloramphenicol ad- ministration, J.A.M.A[r] ...

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