Single-stranded DNA binding proteins
Identification of essential and non essential single stranded DNA binding proteins in a model archaeal organism
... Single-stranded DNA-binding proteins (SSBs) play vital roles in all aspects of DNA metabolism in all three domains of life and are characterized by the presence of one or more OB ...
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Single stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities
... with single-stranded DNA-binding proteins (Ssdps or SSBPs) (Chen et ...Lhx3 proteins with NLI- homodimer lead to a tetrameric complex of 2NLI:2Lhx3, denoted as the V2-tetramer ...
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Reovirus Protein ςNS Binds in Multiple Copies to Single-Stranded RNA and Shares Properties with Single-Stranded DNA Binding Proteins
... (i) binding in multiple units to a nucleic acid molecule in a sequence-independent manner; (ii) protection of the single-stranded nucleic acid from nuclease degradation (data for NS are not shown in ...
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Phylogenetic and Functional Analysis of the Bacteriophage P1 Single-Stranded DNA-Binding Protein
... Single-stranded DNA-binding proteins (SSBs) have been found in all investigated organisms from bacteria to humans (7, ...These proteins have no enzymatic activity, but as their ...
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Characterization of the DNA-Binding Domain of the Avian Y-Box Protein, chkYB-2, and Mutational Analysis of Its Single-Strand Binding Motif in the Rous Sarcoma Virus Enhancer
... that binding to this native double-octamer motif on the RSV LTR is comparable to the binding observed with the synthetic construct X2/E4C1, carrying a perfect repeat of the 12-mer 59-TCGTACCACCT T-39 motif ...
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Role of Single-Stranded DNA Binding Activity of T Antigen in Simian Virus 40 DNA Replication
... tween single-stranded DNA binding and the ability to cause structure distortion of origin DNA, suggesting that single- stranded DNA binding is also needed ...
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Genetic and biochemical identification of a novel single stranded DNA binding complex in Haloferax volcanii
... Single-stranded DNA (ssDNA)-binding proteins play an essential role in DNA replication and ...the DNA. In eukaryotes the ssDNA-binding protein (SSB) is known as ...
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Evidence for DNA Hairpin Recognition by Zta at the Epstein-Barr Virus Origin of Lytic Replication
... a single-stranded imperfect DNA hairpin formed within the top strand of a critical element within the lytic origin ...Zta proteins. (Right) Percentages of binding (from the experiment ...
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Analyses of the Interaction between the Origin Binding Domain from Simian Virus 40 T Antigen and Single-Stranded DNA Provide Insights into DNA Unwinding and Initiation of DNA Replication
... for DNA replication; the references to the individual mutations are ...in binding to double-stranded DNA substrates ...for binding to single-stranded DNA, ...
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The 60-Residue C-Terminal Region of the Single-Stranded DNA Binding Protein of Herpes Simplex Virus Type 1 Is Required for Cooperative DNA Binding
... a binding pattern characteristic of multiple independent sites, in striking contrast with the highly cooper- ative behavior of the full-length ICP8 and ...the binding of the C-terminally truncated ...
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Conserved region 3 of the adenovirus type 5 DNA-binding protein is important for interaction with single-stranded DNA.
... Recognition of DBPs by 2/4 can be roughly correlated with the ability of the proteins to bind to ssDNA, with one exception-the previously isolated CR3 mutant containing a Lys-to-Thr muta[r] ...
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The baculovirus single-stranded DNA binding protein, LEF-3, forms a homotrimer in solution.
... six proteins from Autographa californica multinucleocapsid polyhedrosis virus required for transient DNA replication and has the properties of a single-stranded DNA binding ...
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Characterization of the Single-Stranded DNA Binding Protein Encoded by the Vaccinia Virus I3 Gene
... in DNA binding (modified from references 11, 34, and ...by single-letter abbreviations) separated by variable num- bers of unrelated ...The proteins shown are the I3 protein (39) of vaccinia ...
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Mutations in Sensor 1 and Walker B in the Bovine Papillomavirus E1 Initiator Protein Mimic the Nucleotide-Bound State
... groups—E1 proteins, T antigens, and Rep proteins—have pro- vided important information about how ATP is bound and hydrolyzed by these proteins and the structural consequences that result (1, 4, 7, ...
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Identification of a Region of the Herpes Simplex Virus Single-Stranded DNA-Binding Protein Involved in Cooperative Binding
... major single-strand- DNA-binding protein (SSB) present in infected ...viral DNA (7, ...a DNA-negative phenotype as well as abnormalities in the production of viral proteins (19, ...
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Dominant mutations in mtDNA maintenance gene SSBP1 cause optic atrophy and foveopathy
... Identification of mutations in SSBP1 in families with dominant optic atrophy. We performed whole exome sequencing (WES) in one French family (family A) including multiple patients with ADOA to identify the causative gene ...
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Developing novel single molecule analyses of the single stranded DNA binding protein from Sulfolobus solfataricus
... recruiting proteins to ssDNA who also show a slight affinity for OB ...of DNA could alter how one or many of these factors determine the binding modes of ...of DNA repair or ...
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Plasmid models for bacteriophage T4 DNA replication: requirements for fork proteins.
... Recombination-dependent plasmid replication also strictly required the T4 single-stranded DNA-binding protein gene product 32 [gp321, and replication of origin-containing plasmids was gr[r] ...
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Single molecule FRET analysis of DNA binding proteins
... a single fluorophore reveal reaction intermediates dur- ing transcription ...of single UvrD helicase dynamics on long single-stranded ...on single-stranded DNA to ...
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Displacement of the canonical single stranded DNA binding protein in the Thermoproteales
... SSB proteins, ThermoDBP supplies the essential ssDNA-binding activity, in a dramatic case of non- orthologous gene displacement (34) ...ssDNA binding in the thermoproteales was mediated by an ...
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