Target Selection for Further Gene Expression Studies
Control and target gene selection for studies on UV induced genotoxicity in whales
... Abstract Background: Despite international success in reducing ozone-depleting emissions, ultraviolet radiation (UV) is not expected to decrease for several decades. Thus, it is pressing to implement tools that allow ...
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Reference gene selection for gene expression studies using RT qPCR in virus infected planthoppers
... housekeeping gene expression is not always stable and might vary depending on the samples or treatments, it is necessary to first study the stability of several endogenous gene expression in ...
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Gene selection and classification in autism gene expression data
... the gene expression values of those genes. These studies have generically found the very specific genes related with each type of cancer and based on this, various models have been proposed in the ...
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Effective gene selection techniques for classification of gene expression data
... of gene expression in tumor and normal tissue, the researcher might begin by asking “How do expression levels of gene differ in tumor and normal ...purification, target synthesis, probe ...
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Gene expression-based drug repurposing to target aging
... between expression –age correlations between data sets (Figure ...previous studies suggesting that aging ‐related changes are small and heterogeneous, making them difficult to detect (Somel, Khaitovich, ...
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Gene Selection for Tumor Classification Using Microarray Gene Expression Data
... genome-wide expression data from cancerous tissues gives insight into the gene expression variation of various tumor types, thus providing clues for cancer classification of individual ...microarray ...
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Gene expression and functional studies on psoriatic epidermis
... 19 producing an effective water-impermeable barrier. Steady-state immunity is maintained by various immune cells: the epidermis contains Langerhans cells (LCs) and the dermis contains resident myeloid dendritic cells ...
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On the selection of appropriate distances for gene expression data clustering
... two studies only a small set of both distances and datasets are ...of gene time-series, which are fairly different problems by ...for gene time-series data are not considered in these ...
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Disentangling the Effects of Mutation and Selection on the Evolution of Gene Expression.
... a gene loss scenario, perhaps due to adaptation to a benign environment, as these genes are often found in multiple ...novo gene birth. However, expression data indicates that only 13 genes in this ...
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Feature selection of imbalanced gene expression microarray data
... feature selection instead of use one particular classifier and accepts its outcome as a final ...the target data set, the patients are classified into three categories (high, medium, and standard risk) and ...
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Target selection of soluble protein complexes for structural proteomics studies
... these studies, a tremendous amount of effort has been spent to improve protein solubility by switching the expression system, changing the fusion tags, replacing the expression host, generating a new ...
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Connecting genetics and gene expression data for target prioritisation and drug repositioning
... anti-correlated gene expression profiles of drug ...association studies (GWASs) are of great interest to researchers in the pharmaceutical industry because drug programmes with supporting genetic ...
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EWS FLI1 employs an E2F switch to drive target gene expression
... on target promoters. The mechanism of target co-regulation remained ...on target genes upon EWS-FLI1 modula- ...E2F target and regulating transcription factor expres- sion ...model ...
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Global analysis of gene expression and projection target correlations in the mouse brain
... Recent studies have shown that projection tar- gets in the mouse neocortex are correlated with their gene expression ...those studies to perform a global, integrative analysis of gene ...
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Feature Selection of Gene Expression Data for Cancer Classification: A Review
... Feature selection is an active research area in pattern recognition, statistics, and data mining ...feature selection is to choose a subset of input variables by eliminating features with little or no ...
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Optimal Design and Analysis of Genetic Studies on Gene Expression
... even further—we studied two such ...differential expression caused by these loci by giving more weight to markers in these regions ...favor selection of ge- notypes with a larger number of ...
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Methods for the Reuse of Public Data in Gene Expression Studies.
... random gene selection prior to ...mean expression between the control and clear cell renal cell carcinoma groups (results not ...in gene expression were widespread and relatively large, ...
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An application of sequential meta-analysis to gene expression studies
... 4). Further, the 271 samples from seven experiments are even not enough to draw a conclusion for 9,060 genes when evaluated by Design 1 and 10,994 genes by Design 2 in nonfiltered ...of expression values ...
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A Combined Filter Wrapper Classification Method for Gene Selection from Gene Expression Datasets
... is further optimized and ...of gene selection method to finding any optimal solution as per the ...based gene selection method, as far as sorting out the relevant genes from a high ...
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Gene Age Predicts the Strength of Purifying Selection Acting on Gene Expression Variation in Humans
... of gene origin is associated with many functional traits of eukary- otic ...published studies demonstrate that gene age is associated with the strength of purifying selection acting on ...
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