Temperature-Sensitive Mutation
Multiple functions of raf proto oncogene during development from analysis of a temperature sensitive mutation of Drosophila
... Int J De\' lIiol 38 329 335 (1994) 329 Multiple functions of raf proto oncogene during development from analysis of a temperature sensitive mutation of Drosophila MAMI HATA' YOSHIHIRO H INOUE', MI AE[.] ...
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The new temperature sensitive mutation PA F35S for developing recombinant avian live attenuated H5N1 influenza vaccine
... temperature-sensitive (ts) mutations for developing recombinant avian live attenuated H5N1 influenza vaccine. Findings: A “6 + 2” recombinant virus C4/W1 that contained NA gene and modified HA gene from ...
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Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation.
... this temperature (see below) and increased thermal inactivation of the virus at the higher ...either temperature for nine of the mutant RNAs (A2, A3, A4, A7, A9, A13, A17, A30, and ...
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PHENETHYL ALCOHOL RESISTANCE IN ESCHERICHIA COLI. III. A TEMPERATURE-SENSITIVE MUTATION (dnaP) AFFECTING DNA REPLICATION
... One of these temperature-sensitive mutants dnaP18 (strain KY2750) was chosen for further study, since this mutant seemed to be specifically affected in DNA synthesis and c[r] ...
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Generation and characterization of a temperature-sensitive mutation in the NS-1 gene of the autonomous parvovirus minute virus of mice.
... Parallel cultures of highly synchronized A9 cells infected at 32 and 39°C with either wild-type MVM A and a or Db-2 B and b were assayed for the temporal appearance of transcripts A and [r] ...
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Effect of Temperature-Sensitive Mutation on Activity of the RNA Transcriptase of Vesicular Stomatitis Virus New Jersey
... The heat stability of the mutant ts Bl was similar to that of wild-type virus, and in vitro RNA synthesis was fully restored when the temperature was lowered to 310C after 30 min of prei[r] ...
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A temperature-sensitive mutation of the temperature-regulated SerH3 i-antigen gene of Tetrahymena thermophila: implications for regulation of mutual exclusion.
... DOERDER, 1992b Multiple effects of mutation on expression of alternative cell surface protein genes in Tetra- hymena thermophila. HUTCHINSON, 1991 Mutagenic specificity[r] ...
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Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the I7 gene that encodes a virion component.
... To examine the expression of the 17 gene product during vaccinia virus infection of cultured cells, BSC40 monolayers were infected synchronously with wild-type vaccinia virus and harvest[r] ...
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Effects of a temperature-sensitive mutation in the immediate-early gene of pseudorabies virus on class II and class III gene transcription.
... First, the tsG mutation inhibits the formation of new transcription complexes on class II genes, but does not affect transcription from preestablished transcription complexes formed in t[r] ...
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Drc1p/Cps1p, a 1,3-β-Glucan Synthase Subunit, Is Essential for Division Septum Assembly in Schizosaccharomyces pombe
... a temperature-sensitive mutation, drc1-191, that prevents division septum assembly and causes mutant cells to arrest with a stable actomyosin ...
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A lin-45 raf Enhancer Screen Identifies eor-1, eor-2 and Unusual Alleles of Ras Pathway Genes in Caenorhabditis elegans
... a mutation removing the second SH3 domain of the sem-5/ Grb2 adaptor, a temperature-sensitive mutation in the helical hairpin of let-341/Sos, a gain-of-function mutation affecting a ...
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TEMPERATURE-SENSITIVE NONSENSE SUPPRESSORS IN YEAST
... to cdc8. On the basis of these results we propose that SUP4-2 is a mutation in or very close to the ochre suppressor gene SUPI. c) Conversion of SUP4-2 to a temperature-se[r] ...
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Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene
... missense mutation in beta subunit which predicts substitution of Tyr by His at codon 618, 2 bp downstream from a missense mutation (P616L) that has been reported ...this mutation correlates with the ...
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Introduction of F446I mutation in the K13 propeller gene leads to increased ring survival rates in Plasmodium falciparum isolates
... single mutation after amino acid posi- tion 440 in k13 [7, ...this mutation was not detected in Thai/Cambodia and Thai/Myanmar border regions ...single mutation of F446I with a prev- alence of ...
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DNA clone of avian Fujinami sarcoma virus with temperature-sensitive transforming function in mammalian cells.
... Our result, that the morphology of mouse 3T3 cells transformed by transfection with DNA from a temperature-sensitive strain of FSV is temperature sensitive for a transformation, provides[r] ...
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A delta F508 mutation in mouse cystic fibrosis transmembrane conductance regulator results in a temperature sensitive processing defect in vivo
... common mutation in cystic fibrosis (CF) patients is a deletion of a phenylalanine at position 508 ( D F508) ...This mutation affects correct processing of the protein to its mature, fully glycosylated form ...
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Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
... Preliminary Physiological Characterization of Temperature-Sensitive Mutants of Vesicular Stomatitis Virus Different temperature-sensitive mutants of vesicular stomatitis virus have been [r] ...
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Mechanism of Activation of the Caenorhabditis elegans ras Homologue let-60 by a Novel, Temperature-Sensitive, Gain-of-Function Mutation
... since overexpression of GNEFs can overcome the ef- fects of dominant-negative Ras (SIGAL et ul. In summary, our results indicate that the L19F substi- tution may primarily[r] ...
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INDIRECT SUPPRESSION INVOLVING BEHAVIORAL MUTANTS WITH ALTERED NERVE EXCITABILITY IN DROSOPHILA MELANOGASTER
... W e report here that even under permissive temperatures, napts (no action potential, temperature-sensitive) , a temperature-sensitive paralytic mutation that blocks acti[r] ...
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A Single Mutation Responsible for Temperature-Sensitive Entry and Assembly Defects in the VP1-2 Protein of Herpes Simplex Virus
... USP region itself contains no amino acid substitutions, and considering that the USP can fold and likely function in isola- tion (31), we believe it unlikely that the substitution at position 1453 (or at the other ...
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