[PDF] Top 20 Analysis of Gene Sets Based on the Underlying Regulatory Network
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Analysis of Gene Sets Based on the Underlying Regulatory Network
... on gene set analysis can be broadly classified into permutation-based methods motivated by the GSEA paper and model-based approaches that make specific distributional assumptions about the ... See full document
21
Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet
... interaction network comprising en- riched biological processes, their transcriptional regulators and associated changes in physiological ...multi-layered network model reveals that early eWAT adaptation to ... See full document
11
Gene regulatory network reveals oxidative stress as the underlying molecular mechanism of type 2 diabetes and hypertension
... selected based on the following criteria’s: i) Genes experimentally proved to be associated with any one of the above mentioned diseases, ii) Genes experimentally proved to be associated with two or more concerned ... See full document
18
Identification of epigenetically altered genes and potential gene targets in melanoma using bioinformatic methods
... identified. Gene ontology (GO) and pathway enrichment analyses of the DEGs were carried ...transcriptional regulatory network was constructed based on the interactions between the tran- ... See full document
7
Lessons from a gene regulatory network: echinoderm skeletogenesis provides insights into evolution, plasticity and morphogenesis
... Recent analysis has shown that NSM transfating is associated with the activation of many (probably all) of the downstream biomineralization genes in the micromere-PMC GRN (Ettensohn et ...the regulatory ... See full document
11
Multilayer Perceptron based Model of Large Scale Gene Regulatory Network
... Performance analysis of the model on ...polB gene happens to inhibit almost all other genes, whereas lexA gene has been reported to inhibit all other genes in ...repair network genes on KEGG ... See full document
10
Genome wide analysis of the skeletogenic gene regulatory network of sea urchins
... Cuffdiff analysis was relatively stringent (estimated false discovery ...with Gene Ontology (GO) terms associated with metabolism, DNA replication, protein translation and other likely housekeeping ... See full document
13
Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system
... The reconstituted networks reveal a central role of Fgf8/17/18 in generating regional patterns of gene expression. Fgf8/17/18 is expressed at the late gastrula stage in A9.30 (see Fig. 5C), which forms most of the ... See full document
9
Cis-regulatory analysis of the sea urchin delta gene : validating the architecture of the gene regulatory network model for micromere lineage specification
... Blastula stage embryo at about 9 th cleavage (about 15 h after fertilization). (C) Mesenchyme blastula stage embryo (about 24 h after fertilization). (D) Late gastrula stage embryo (about 55 h after fertilization). The ... See full document
174
Regulatory networks controlling ANAC092 expression during different stress responses in Arabidopsis thaliana
... A gene-regulatory network is believed to act at the centre of the circadian rhythm in ...controlling gene expression central to circadian rhythms are ...the underlying mechanisms that ... See full document
272
Inferring Drosophila gap gene regulatory network: pattern analysis of simulated gene expression profiles and stability analysis
... temporal gene expression data ...obtained gene circuits essen- tially by visual inspection of the simulated patterns, mainly because of an insufficient number of ...the network structure has been ... See full document
10
Statistical and Gene Regulatory Network Analysis of Monolignol Biosynthetic Genes in Populus trichocarpa.
... MYB was the first transcription factor identified in plants 27 years ago; COLORED1 that translate into MYB domain protein for control anthocyanin in maize (Paz-Ares et al., 1987). After that time MYB transcription ... See full document
239
Dissection of gene regulatory networks underlying patterning and morphogenesis in the C elegans vulva
... a gene necessary for negative regulation of ceh-2 expression in the 18 vulE and vulF cells (Figure 1A– ...rate. Analysis of the nhr-67 deletion allele ok631 revealed severe defects in early larval ... See full document
109
Construction of microRNA and transcription factor regulatory network based on gene expression data in cardiomyopathy
... miRNA analysis, we used Targetscan [9], miRanda [10] and Pita [11] for miRNA target DEGs ...TF analysis, we obtained TF binding sites and the coordinate’s position information of human being from the ... See full document
6
p42.3 gene expression in gastric cancer cell and its protein regulatory network analysis
... similarity based on the molecular inner spatial density distribution, which the protein molecule space is performed concentric spherical shell division and got many shell structure space units with a certain ... See full document
10
Mean field analysis of a spatial stochastic model of a gene regulatory network
... parameter sets which yield time series which are occupied approximately 50% of the time and which we would expect to yield oscillatory dynamics in the mRNA and protein ...parameter sets could yield ... See full document
34
Learning Gene Regulatory Network from Microarrays Based on Bayesian Network
... of gene regulatory systems and gene regulatory ...the network of gene regulatory from ...and analysis methods in this area, since the observation data are vary ... See full document
7
Pathway analysis of genes identified through Post-GWAS to understand prostate cancer aetiology
... mechanisms underlying prostate ...development gene networks suggesting prostate cancer may result from the accumulation of the effects of functional variants through multiple gene sets and ... See full document
27
Research and Application of Differential Equation System in Gene Regulation Network and Metabolic Pathway
... of gene sequencing has also decreased dramatically with the development of ...of gene research has gradually shifted to the functional analysis of ...of gene regulation network ... See full document
7
Dynamical Analysis of Regulatory Interactions in the Gap Gene System of Drosophila melanogaster
... the regulatory interactions Wieschaus 1980; Nu ¨ sslein-Volhard et ...The underlying gap gene ...segmentation gene network is a hierarchical dy- edge of gap gene regulation is ... See full document
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