[PDF] Top 20 Detection of herpes simplex virus type 1 latency-associated transcript expression in trigeminal ganglia by in situ reverse transcriptase PCR.
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Detection of herpes simplex virus type 1 latency-associated transcript expression in trigeminal ganglia by in situ reverse transcriptase PCR.
... LAT expression detected by ISH as a measure of the number of genome- containing cells underestimates the number of latent HSV genome-containing cells in a trigeminal ...LAT expression, the majority ... See full document
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Herpes Simplex Virus Type 1 Latency-Associated Transcript Expression Protects Trigeminal Ganglion Neurons from Apoptosis
... infected trigeminal ganglia were identified by morphology and apoptotic neurons were counted ...different trigeminal gan- glia as possible to provide a wide distribution of ...in trigeminal ... See full document
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The Herpes Simplex Virus 1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8+ T Cells in Latently Infected Trigeminal Ganglia: a Novel Immune Evasion Mechanism
... quantitative reverse transcription-PCR (qRT-PCR) ...PD-L1 expression in JWLAT LAT ⫹ -expressing Neuro2A cells and JW- ⌬ LAT LAT ⫺ Neuro2A cells as determined by ... See full document
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Structural and kinetic analyses of herpes simplex virus type 1 latency associated transcripts in human trigeminal ganglia and in cell culture
... human trigeminal ganglia, the smaller (1.35 kb) HSV-1 transcript differs from the larger ...Its expression is inhibited by cycloheximide or acyclovir, indicating this LAT is synthesized ... See full document
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The abundant latency-associated transcripts of herpes simplex virus type 1 are bound to polyribosomes in cultured neuronal cells and during latent infection in mouse trigeminal ganglia.
... the detection of the 1.5-kb LAT in NA4 cells by RT-PCR, the same analysis was carried out with an- other pair of primers, P8 and P9, also flanking the splicing region but covering another sequence in the ... See full document
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A herpes simplex virus type 1 latency-associated transcript mutant reactivates with normal kinetics from latent infection.
... Expression of herpes simplex virus type 1 latency-associated transcripts in the trigeminal ganglia of mice during acute infection and reactivation of latent infection.. Expression of her[r] ... See full document
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Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency.
... Herpes simplex virus type 1 (HSV-1), an alphaherpesvirus, is neurotropic and establishes lifelong latency in the nervous ...of virus into axon terminals and viral ... See full document
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The Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer/rcr Is Hyperacetylated during Latency Independently of LAT Transcription
... ing latency suggested that the process of active transcription itself, and the recruitment of histone acetyltransferases by the RNA Pol II complex, was responsible for this acetylation pro- ...wild type) ... See full document
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Two herpes simplex virus type 1 latency-active promoters differ in their contributions to latency-associated transcript expression during lytic and latent infections.
... Herpes simplex virus type 1 (HSV-1) establishes latency in human sensory ganglia, during which time the viral genome is transcriptionally silent with the exception ... See full document
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The Locus Encompassing the Latency-Associated Transcript of Herpes Simplex Virus Type 1 Interferes with and Delays Interferon Expression in Productively Infected Neuroblastoma Cells and Trigeminal Ganglia of Acutely Infected Mice
... The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) is the only abundant viral transcript expressed in latently infected ... See full document
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Neuronal Subtype Determines Herpes Simplex Virus 1 Latency-Associated-Transcript Promoter Activity during Latency
... lishes latency in trigeminal ganglia (TG), while HSV-2 usually infects the genital epithe- lium and establishes latency in dorsal root ganglia (DRG) ...sensory ganglia, and ... See full document
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A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation.
... Latency-associated transcript (LAT) promoter deletion mutants of herpes simplex virus type 1 have a reduced capacity to reactivate following adrenergic induction in ... See full document
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Held, Kathrin (2012): Control of herpes simplex virus type 1 latency in human trigeminal ganglia. Dissertation, LMU München: Fakultät für Biologie
... infectious virus. Free HSV-1, released from productively infected cells, can then enter sensory nerve fibres innervating the site of ...The virus then travels via retrograde transport to the cell ... See full document
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The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency.
... in situ PCR to quantify latent infections established by several LAT ...wild type in its ability to reactivate in a timely manner in an in vitro cocultivation assay, as well as in establishment as ... See full document
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The High Prevalence of Herpes Simplex Virus Type 1 DNA in Human Trigeminal Ganglia Is Not a Function of Age or Gender
... of herpes simplex virus type 1 (HSV-1) DNA in human trigeminal ganglia (TG) with respect to age, gender, and postmortem interval ... See full document
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Replication of Herpes Simplex Virus Type 1 within Trigeminal Ganglia Is Required for High Frequency but Not High Viral Genome Copy Number Latency
... the virus replication cycle (8, ...of latency (for a review, see reference ...of virus into the sciatic nerve trunk, treatment with antiviral nucleoside analogs did not signifi- cantly reduce the ... See full document
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Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.
... By using various fragments and deletion constructs, this promoter activity 3269 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest To identify promoter regions which contr[r] ... See full document
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Analysis of Protein Expression from within the Region Encoding the 2.0-Kilobase Latency-Associated Transcript of Herpes Simplex Virus Type 1
... LAT-GFP virus during either productive or latent ...recombinant virus, vLAT-GFP, was produced by cotransfection of the plasmid p⌬CMV(H)GFP and parental F strain DNA, followed by several rounds of plaque ... See full document
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Induction of cellular transcription factors in trigeminal ganglia of mice by corneal scarification, herpes simplex virus type 1 infection, and explantation of trigeminal ganglia.
... oct-i expression in neuronal and nonneuronal cells of trigeminal ganglia detected by in situ hybridization as a function of time after corneal scarification A, corneal scarification foll[r] ... See full document
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Competitive quantitative PCR analysis of herpes simplex virus type 1 DNA and latency-associated transcript RNA in latently infected cells of the rat brain.
... Lane 1, day 2 extract from contralateral region of infected hippocampus amplified with carbonic anhydrase II primers; lane 2, day 2 extract from contralateral region of infected hippocam[r] ... See full document
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