[PDF] Top 20 Evolving gene regulatory networks for cellular morphogenesis
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Evolving gene regulatory networks for cellular morphogenesis
... In general, the models mentioned above do not include individual cell morphology: Cells are represented as circles or squares, of equal or varying size. The model used by [9] does support anisotropic cell shapes; ... See full document
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Lessons from a gene regulatory network: echinoderm skeletogenesis provides insights into evolution, plasticity and morphogenesis
... new cellular interactions that suppressed the skeletogenic potential of the ancestral population, by inactivating a key, Alx1-mediated subcircuit of the skeletogenic ...genomic regulatory state), which has ... See full document
11
Diffusion driven oscillations in gene regulatory networks
... Gene regulatory networks (GRNs) play an important role in maintaining cellular function by correctly timing key pro- cesses such as cell division and ...to gene-sites in the nucleus ... See full document
22
RNA-Seq analysis uncovers non-coding small RNA system of Mycobacterium neoaurum in the metabolism of sterols to accumulate steroid intermediates
... four regulatory networks were constructed to reveal the direct and/or indirect interactions between sRNA candidates and their target genes in four groups, including wide type Mn with vs without sterol ... See full document
17
Cellular responding kinetics based on a model of gene regulatory networks under radiotherapy
... of cellular response in fighting against genome stresses under different IR dose ...in cellular responding DNA damage under radiotherapy begin to decrease as the strength of IR ex- ceeds a certain maximal ... See full document
10
Developmental Regulation of an Adhesin Gene during Cellular Morphogenesis in the Fungal Pathogen Candida albicans
... In parallel studies, Kim and coworkers (33) made similar observations about the regulation of a second hypha-specific gene, HWP1. The HWP1 promoter also contains two activation regions. One region, which binds an ... See full document
11
Fan-out in gene regulatory networks
... Engineering relies on modular composition, that is, the ability to combine functional units with the knowledge that the intrinsic properties of each module is unaffected to a large degree by the composition. In biology, ... See full document
14
Regulatory control of signal transduction during morphogenesis in Drosophila
... The generation of cell diversity depends on a series of events which occur during embryonic development. This set of events have to be coordinated in order to achieve the spatial organization which will allow normal ... See full document
6
Evolving Boolean regulatory networks with epigenetic control
... combination of traits. The fitness contribution of each gene is found from its individual table. These fitnesses are then summed and normalised by N to give the selective fitness of the total genome (see ... See full document
21
Heart morphogenesis gene regulatory networks revealed by temporal expression analysis
... the gene regulatory interactions driving major expression patterns in the heart during looping ...looping morphogenesis, it is still unclear how the timing between gene regulatory ... See full document
12
Dissection of gene regulatory networks underlying patterning and morphogenesis in the C elegans vulva
... An RNA interference (RNAi) screen of 508 known and putative transcription factors encoded in the C. elegans genome (see Table S1) was conducted in a ceh-2::YFP reporter background. At the time we performed the screen, ... See full document
109
Construction of gene regulatory networks using biclustering and bayesian networks
... of gene cov- erage (25%), it showed better performance with one of its biclusters having 11 genes matching response to oxidative stress ...and cellular response to starvation functions, ... See full document
20
Gene Regulatory Networks and Transcriptional Mechanisms that Control Myogenesis
... Subsequently Foxc2 remains high in the sclerotome and is important for bone and cartilage formation. In the dermo- myotome, expression is reduced except in the hypaxial domain. When the balance between Pax3 and Foxc2 ... See full document
14
Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas
... genome gene expression data obtained from lung tissue of wild type, non-transgenic control animals were compared to lung tumors of transgenic mice (see Supplementary Figure S1 for the strategy of data ...genome ... See full document
24
Investigating the Effects of Imputation Methods for Modelling Gene Networks Using a Dynamic Bayesian Network from Gene Expression Data
... The edges between YOR263C and YOR264W were the most conspicuous features in the sub- network. This is primarily because both genes are located adjacent to one another on the DNA strand of chromosome XV. However, the ... See full document
8
Modelling and control of gene regulatory networks for perturbation mitigation
... to gene regulatory net- works that may arise due to disease and/or environmental ...of gene regulatory ...example gene regulatory network, and design a genetic feedback ... See full document
31
CyNetworkBMA: a Cytoscape app for inferring gene regulatory networks
... In this paper, we present CyNetworkBMA, a Cytoscape app that brings the powerful features of networkBMA to a wider biomedical community. CyNetworkBMA offers an alternative, GUI-based way of running BMA network inference, ... See full document
7
Analysis of stage specific gene perturbations and characterisation of two novel F box genes during flower development in Arabidopsis thaliana
... In the same manner as above, enriched GO terms were identified in the upregulated genes of both gene sets. The most enriched terms returned for upregulated genes in the AG knockdown series were predominantly ... See full document
283
Laws for the dynamics of regulatory networks
... a gene whose product directly or indirectly represses its own synthesis (a typical negative ...a gene product is subject to decay and/or dilution, its concentration will decrease, resulting in release of ... See full document
7
Extracting Regulatory Gene Expression Networks From Pubmed
... Before matching these names against the POS- tagged corpus, the list of names was expanded to include different orthographic variants of each name. Firstly, the names were allowed to have various combinations of ... See full document
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