[PDF] Top 20 Expression of Progranulin in a Mouse Model of Newborn Hypoxic-ischemic Brain Damage
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Expression of Progranulin in a Mouse Model of Newborn Hypoxic-ischemic Brain Damage
... The brain tissues of neonatal mice (after HI 3 days) from HI groups were carefully removed and made into frozen sections and stored at － 80°C until next ... See full document
7
Grape Seed Proanthocyanidin Extract Down-Regulates Autophagic Proteins (LC3II and Beclin-1) in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury
... severe brain injury with various causes in the perinatal ...mild-to-moderate brain injury, but hypothermia therapy has little effect in patients with severe HIE brain injuries ... See full document
5
Melatonin alleviates brain and peripheral tissue edema in a neonatal rat model of hypoxic-ischemic brain damage: the involvement of edema related proteins
... the brain assessed with ...ZO-1 expression, may be related to the damage of tight junctions between tubules and renal interstitial, which tends to lead to vasogenic ...mRNA expression in the ... See full document
13
Research on the Effect of Electroacupuncture on MDM2 Expression in a Hypoxic-Ischemic Encephalopathy Rat Model
... the expression of mdm2 in the neurons of model rats began to be down-regulated from 1st day to 21th day after cerebral ischemia-hypoxia, but the downward trend slowed down gradually, suggesting that the ... See full document
8
Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats
... rat brain tis- sue and hippocampus ...immature brain remained unclear. In human premature infant, expression of EAAT2 was observed in pre-oligo- dendrocytes which might be the cause of white matter ... See full document
10
Original Article Bax inhibiting peptide reduces apoptosis in neonatal rat hypoxic-ischemic brain damage
... Neonatal hypoxic ischemic encephalopathy (HIE) has been reported to induce apoptosis in ...during hypoxic- ischemic brain damage ...The expression of cytochrome c and ... See full document
8
Clinical pathophysiology of hypoxic ischemic brain injury after cardiac arrest: a “two hit” model
... increasing expression of antia- poptotic proteins such as Bcl-2 [56, ...severe damage to the key centers of thermoregulation, including the hypo- thalamus ... See full document
10
Original Article Different extent of hypoxic-ischemic brain damage in newborn rats: histopathology, hemodynamic, virtual touch tissue quantification and neurobehavioral observation
... mal model, we still encountered with some dif- ...experimental model making, we should pay attention to several ...the hypoxic cabin, if the tempera- ture is too low, brain damages may become ... See full document
11
Original Article The expression of PI3K/Akt signaling pathway and PTEN in hippocampus of the brain and the correlation with cognitive impairment after neonatal hypoxic ischemic brain damage in rats
... protein expression was sig- nificantly inhibited in Wortmannin-treated HIBD group rats compared with that in DMSO-treated HIBD group and HIBD model group rats (P < ...HIBD model group (P > ... See full document
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Original Article Effects of mannitol on hypoxic-ischemic brain edema and aquaporin-4 expression in neonatal rats
... Abstract: Brain edema after hypoxic-ischemic brain damage (HIBD) is a serious problem in ...alleviate brain edema by regulating the expression of ...rat model of ... See full document
5
Resveratrol post-treatment protects against neonatal brain injury after hypoxia-ischemia
... traumatic brain injury and cerebral ischemia/reperfusion injury [9, ...neonatal hypoxic- ischemic brain ...a model of neonatal hypoxic-ischemic brain injury, which ... See full document
15
Carbon Dioxide Protects the Perinatal Brain From Hypoxic-Ischemic Damage: An Experimental Study in the Immature Rat
... combined with either 0, 3, 6, or 9% carbon dioxide (CO2) for 2.5 hours at 37#{176}C.Survivors underwent neuropatho- logic examination at 30 days of postnatal age, and their brains were c[r] ... See full document
9
Measurement of Lactate Content and Amide Proton Transfer Values in the Basal Ganglia of a Neonatal Piglet Hypoxic Ischemic Brain Injury Model Using MRI
... the brain remains unchanged for a short period after HI insult, the change of APT signal may be primarily related to pH ...in brain tis- sues within a short time after HI insult, primarily depending on ... See full document
8
Neuro Developmental Outcome of New Borns with Hypoxic Ischemic Encephalopathy
... 9. Asakura H. et al, Perinatal risk factors related to neurologic outcomes of term new borns with asphyxia at birth : a prospective study. Of the 152 newborns in 1 year prospective follow up. The incidence of a poor ... See full document
97
Summary Proceedings From the Neurology Group on Hypoxic-Ischemic Encephalopathy
... 21. Mizrahi EM. Consensus and controversy in the clinical man- agement of neonatal seizures. Clin Perinatol. 1989;16:485–500 22. Hall RT, Hall FK, Daily DK. High-dose phenobarbital therapy in term newborn infants ... See full document
8
Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury
... the brain is a major target for glucocorticoids and the developing brain is inherently more susceptible to drug-induced alterations than the adult brain [3], there is concern that neonatal DEX ... See full document
11
Mri patterns of hypoxic ischemic encephalopathy in term infants and correlation with neurosonographic appearance & clinical outcome
... In a review article titled Prognostic tests in term neonates with Hypoxic Ischemic ncephalopathy: A systematic Review(8), the following results were published. In imaging, diffusion weighted MRI performed ... See full document
5
Neuropathology in intrauterine growth restricted newborn piglets is associated with glial activation and proinflammatory status in the brain
... piglet brain [10, ...piglet brain which may be indicative of ongoing impairment that extends beyond that which occurred during fetal ...of brain analysis (fetal vs postnatal) or the method of ... See full document
13
Low plasma progranulin levels in children with autism
... system, progranulin is widely expressed during early neural development but later on, its expression becomes restricted to specific neuronal popula- tions including cortical neurons in several layers, ... See full document
6
Original Article Granulocyte-colony stimulating factor in combination with AMD3100 confers greater neuroprotection after hypoxic-ischemic brain damage than a solitary treatment in mice
... AMD3100, a novel small molecule that acts as a specific CXCR4 antagonist, is shown with an efficient ability for bone marrow HSC mobiliza- tion with clinical therapeutic potential [9]. In 2008, it was approved as a HSC ... See full document
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