[PDF] Top 20 Identification of Conserved and Variable Structures in the Human Immunodeficiency Virus gp120 Glycoprotein of Importance for CXCR4 Binding
Has 10000 "Identification of Conserved and Variable Structures in the Human Immunodeficiency Virus gp120 Glycoprotein of Importance for CXCR4 Binding" found on our website. Below are the top 20 most common "Identification of Conserved and Variable Structures in the Human Immunodeficiency Virus gp120 Glycoprotein of Importance for CXCR4 Binding".
Identification of Conserved and Variable Structures in the Human Immunodeficiency Virus gp120 Glycoprotein of Importance for CXCR4 Binding
... Both purified and phycoerythrin (PE)-conjugated anti-CCR5 (2D7) and -CXCR4 (12G5) monoclonal antibodies (MAbs) and the purified isotype control (mouse immunoglobulin G2a [IgG2a]) were obtained from Pharmingen (San ... See full document
10
Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding.
... in gp120 conformation, some of the effects of dele- tions in the variable loops on the 17b and 48d epitopes are dependent upon the context in which binding of the antibodies to the gp120 ... See full document
11
CD4 Binding Site Antibodies Inhibit Human Immunodeficiency Virus gp120 Envelope Glycoprotein Interaction with CCR5
... ⌬V1/V2 gp120 glycoprotein revealed that the IgG1b12 antibody did not recognize this protein as efficiently as the other CD4BS antibodies (data not ...⌬V1/V2 gp120 glycoproteins efficiently (data not ... See full document
6
A V3 Loop-Dependent gp120 Element Disrupted by CD4 Binding Stabilizes the Human Immunodeficiency Virus Envelope Glycoprotein Trimer
... well conserved among naturally occurring group M (major group) HIV-1 strains (30, ...This conserved length may be important for aligning the two CCR5-binding elements of the V3 ...CCR5 ... See full document
15
Oligomeric Modeling and Electrostatic Analysis of the gp120 Envelope Glycoprotein of Human Immunodeficiency Virus
... The human immunodeficiency virus envelope glycoproteins, gp120 and gp41, function in cell entry by binding to CD4 and a chemokine receptor on the cell surface and orchestrating the ... See full document
12
Importance of the V1/V2 Loop Region of Simian-Human Immunodeficiency Virus Envelope Glycoprotein gp120 in Determining the Strain Specificity of the Neutralizing Antibody Response
... on conserved elements within gp120 that are able to access these epitopes in the context of the mature trimer spike on the surface of the ...V1/V2 variable loop is the principal determinant of ... See full document
13
Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding
... identified human immunodeficiency vi- rus type 1 gp120 residues critical for CD4 binding (37), resi- dues whose involvement was later confirmed when the crystal structure of gp120 was ... See full document
10
Identification of Determinants on a Dualtropic Human Immunodeficiency Virus Type 1 Envelope Glycoprotein That Confer Usage of CXCR4
... or CXCR4 in conjunction with CD4 was ...The variable regions of HIV-1 DH12 gp120 transferred into the chimeric envelope are indicated at the ... See full document
7
Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein.
... C5 gp120 regions without globally disrupting the gp120 conforma- tion suggests that the N and C termini of gp120 are somewhat exposed, flexible ...V3 variable loops, which can be removed from ... See full document
10
The Mannose-Dependent Epitope for Neutralizing Antibody 2G12 on Human Immunodeficiency Virus Type 1 Glycoprotein gp120
... HIV-1 gp120 monomer are shown in three different ...shows gp120 as viewed from the target cell membrane, looking towards the ...core gp120 oriented such that the viral membrane would be positioned ... See full document
13
Identification of gp120 Binding Sites on CXCR4 by Using CD4-Independent Human Immunodeficiency Virus Type 2 Env Proteins
... Human immunodeficiency virus (HIV) and simian (SIV) immunodeficiency virus entry is mediated by binding of the viral envelope glycoprotein (Env) to CD4 and chemokine ... See full document
12
Cooperation of the V1/V2 and V3 Domains of Human Immunodeficiency Virus Type 1 gp120 for Interaction with the CXCR4 Receptor
... the gp120 core (30) allowed definition of a CCR5-binding site formed by juxtaposition of residues from different conserved domains ...these conserved residues of gp120 also participate ... See full document
8
Dissociation of the CD4 and CXCR4 Binding Properties of Human Immunodeficiency Virus Type 1 gp120 by Deletion of the First Putative Alpha-Helical Conserved Structure
... of gp120 would further our understanding of the interactions between the virus and target ...of gp120 has resulted in the development of structure-function studies of this protein by different ap- ... See full document
9
Binding of Recombinant Feline Immunodeficiency Virus Surface Glycoprotein to Feline Cells: Role of CXCR4, Cell-Surface Heparans, and an Unidentified Non-CXCR4 Receptor
... and CXCR4 rather than an interaction between gp95 and HSPGs, Jurkat ...gp95-Fc binding for cells treated in the absence or presence of heparinase, ...and CXCR4, consistent with a recent study in ... See full document
12
Binding of Human Immunodeficiency Virus Type 1 gp120 to CXCR4 Induces Mitochondrial Transmembrane Depolarization and Cytochromec-Mediated Apoptosis Independently of Fas Signaling
... of gp120 at the surface of 8.E5 cells and the stable gp120-transfected HEK cell line (black histograms) are compared to the parental CEM and HEK lines (white histograms), as detected by flow ... See full document
14
Complex Determinants in Human Immunodeficiency Virus Type 1 Envelope gp120 Mediate CXCR4-Dependent Infection of Macrophages
... using CXCR4 (T-X4), or dually lymphocyte and macrophage tropic using CXCR4 alone or in combination with CCR5 (D-X4 or ...envelope gp120 V3 is necessary and sufficient for M-R5 and T-X4 phenotypes, ... See full document
12
Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein.
... To compare the ability of different gpl20 mutants to associate with the gp4l transmembrane glycoprotein, the levels of envelope glycoproteins in the lysates and supernatants of the trans[r] ... See full document
5
Functional interaction of constant and variable domains of human immunodeficiency virus type 1 gp120.
... To examine this question further, the 308ile codon change was introduced into the original noninfectious 267gln HIV-1 proviral clone by oligonucleotide-directed mutagene- pNL4-3 wild typ[r] ... See full document
6
Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity.
... 5007-5012 0022-538X/91/095007-06$02.00/0 Copyright © 1991, American Society for Microbiology Effects of Changes in gpl20-CD4 Binding Affinity on Human Immunodeficiency Virus Type 1 Envel[r] ... See full document
6
Characterization of human immunodeficiency virus type 1 gp120 binding to liposomes containing galactosylceramide.
... Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type I recombinant human immunodeficiency virus envelope glycoprotein gp120 expresse[r] ... See full document
9
Related subjects