[PDF] Top 20 Lentivirus Vectors Using Human and Simian Immunodeficiency Virus Elements
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Lentivirus Vectors Using Human and Simian Immunodeficiency Virus Elements
... Lentivirus vectors based on human immunodeficiency virus (HIV) type 1 (HIV-1) constitute a recent devel- opment in the field of gene ...HIV-1-derived vectors is their ability to ... See full document
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Inhibition of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by HIV-1-Based Lentivirus Vectors Expressing Transdominant Rev
... Retrovirus vectors expressing transdominant-negative mutants of Rev (TdRev) inhibit human immunode- ficiency virus type 1 (HIV-1) replication by preventing the nuclear export of unspliced viral ... See full document
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Identification of a Human Immunodeficiency Virus Type 2 (HIV-2) Encapsidation Determinant and Transduction of Nondividing Human Cells by HIV-2-Based Lentivirus Vectors
... nucleotides [nt]), and deletions in c markedly attenuate geno- mic mRNA encapsidation. In addition, attachment of c (and more optimally, the c9 segment, which includes c plus a por- tion of gag) to heterologous test RNAs ... See full document
10
Comparison of Gene Transfer Efficiencies and Gene Expression Levels Achieved with Equine Infectious Anemia Virus- and Human Immunodeficiency Virus Type 1-Derived Lentivirus Vectors
... all human cell lines ...EIAV vectors is unclear; however, it is hypothesized that gene silencing with retroviral vectors occurs through a two-step mechanism, where methylation of transcriptional ... See full document
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Development of Minimal Lentivirus Vectors Derived from Simian Immunodeficiency Virus (SIVmac251) and Their Use for Gene Transfer into Human Dendritic Cells
... approach using high-fidelity PCR amplification to generate specific SIV DNA sequences, we have been able to construct the minimal vectors SIV-RMES3 and SIV-RMES4, which combine small size and the ability to ... See full document
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Pseudotyped Lentivirus Vectors Derived from Simian Immunodeficiency Virus SIVagm with Envelope Glycoproteins from Paramyxovirus
... novel lentivirus vectors based on simian immunodeficiency virus from African green monkey (SIVagm) pseudotyped with Sendai virus (SeV) envelope ...stomatitis virus G ... See full document
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Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2
... gene using NsiI and MfeI ...mutagenesis. Human and sooty mangabey tetherin-bst2 genes were expressed from pCG expression vectors ...stomatitis virus glycoprotein (VSV-G) has been previously ... See full document
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Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1
... stomatitis virus glycoprotein (VSV-G). Pseudo- typed vectors can be concentrated by simple ultracentrifuga- tion without significant loss of infectivity (3, ...HIV vectors for use in gene ... See full document
6
Inoculation of baboons and macaques with simian immunodeficiency virus/Mne, a primate lentivirus closely related to human immunodeficiency virus type 2.
... 6 0022-538X/88/062091-11$02.00/0 Copyright © 1988, American Society for Microbiology Inoculation of Baboons and Macaques with Simian Immunodeficiency Virus/Mne, a Primate Lentivirus Clos[r] ... See full document
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Efficient encapsidation of human immunodeficiency virus type 1 vectors and further characterization of cis elements required for encapsidation.
... Retroviral vectors are used as tools to transduce foreign se- quences into ...these vectors was cotransfected along with the helper plasmid pMSMBA, and the relative encapsidation effi- ciency of each of ... See full document
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Simian Immunodeficiency Virus Integration Preference Is Similar to That of Human Immunodeficiency Virus Type 1
... therapy vectors strongly favor transcription units and gene-dense regions in the rhesus monkey genome ...in human tissue culture cells by acute infection with a replica- tion-competent SIV ... See full document
6
Construction and characterization of replication-competent simian immunodeficiency virus vectors that express gamma interferon.
... Dnef vectors expressing human IFN- g as a step toward development of a safer and more efficacious attenuated live vaccine for ...AIDS. Human IFN- g is fully active in monkey cells, induces an ... See full document
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Differential Restriction of Human Immunodeficiency Virus Type 2 and Simian Immunodeficiency Virus SIVmac by TRIM5α Alleles
... HIV-1 virus by transfection of 293T cells as described ...by using the QuikChange protocol ...PCR using HIV-2 packaging plasmid pSVR NB as a template and oligonucleotides fwd ... See full document
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Experimental Adaptive Evolution of Simian Immunodeficiency Virus SIVcpz to Pandemic Human Immunodeficiency Virus Type 1 by Using a Humanized Mouse Model
... primate lentivirus infections, including APOBEC3 (apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3) (21) and tetherin (also known as bone marrow stromal antigen 2 [BST2]) (22, ...antagonizes ... See full document
21
Viral Determinants of Integration Site Preferences of Simian Immunodeficiency Virus-Based Vectors
... Random insertion site generation. For comparison of data in terms of pref- erential integration patterns, we created a random sequence set consisting of 2,000 sequences (F. A. Giordano, B. Fehse, A. Hotz-Wagenblatt, S. ... See full document
6
Limited Protection from a Pathogenic Chimeric Simian-Human Immunodeficiency Virus Challenge following Immunization with Attenuated Simian Immunodeficiency Virus
... in human clinical trials ...the virus to grow less efficiently and to induce a diminished immune response ...immunizing virus to cause damage to the immune system and second by the level of the ... See full document
9
Characterization of Simian Immunodeficiency Virus SIVSM/Human Immunodeficiency Virus Type 2 Vpx Function in Human Myeloid Cells
... 8:8:4. Vectors were purified from the supernatant of transfected cells by ultracentrifugation through a double-step sucrose cushion (45% and 25%, wt/vol) ... See full document
11
Induction of AIDS by simian immunodeficiency virus lacking NF-kappaB and SP1 binding elements.
... of human immunodeficiency virus type 1 (HIV-1) (2, 6, 10, 11, 18, 21, ...These elements are located in the U3 region of the long ter- minal repeats (LTRs) just upstream of the TATA ...lated ... See full document
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Detection of Simian Immunodeficiency Virus in Diverse Species and of Human Immunodeficiency Virus Type 2 by Using Consensus Primers within the pol Region
... Human immunodeficiency virus type 2 (HIV-2) is the result of cross-species transmission of simian immu- nodeficiency virus (SIV) from sooty mangabey monkeys to ...detect ... See full document
5
A Pathogenic Threshold of Virus Load Defined in Simian Immunodeficiency Virus- or Simian-Human Immunodeficiency Virus-Infected Macaques
... a lentivirus infection is established relatively early after inoculation when evaluated with one particular SIV strain ...the virus strain examined, a certain threshold virus load is predictive of a ... See full document
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