[PDF] Top 20 Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma

... excess risk of haematological malignan- cies in SLE is necessarily due to genetic factors; expo- sures within the environment may also be at ...a risk for lymphoma appeared to be independent of other ... See full document

... Hepatitis B virus (HBV) infection remains a heavy health burden worldwide, especially in middle-low incomes ...hepatitis B (CHB) affects an estimated 400 million people and increased risk of ... See full document

... Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and displays heterogeneous clinical and molecular ...expression–based risk score ... See full document

... to cell cycle arrest and apop- tosis in Primary effusion lymphoma (PEL) cells, which is an aggressive B-cell lymphoma associated with Kaposi’s sarcoma-associated herpesvirus infection ... See full document

... In a previous study, Chow et al 13 combined I-PET with IPI as a nomogram based on a bootstrapped Cox regres- sion model. However, the cutoff value of this nomogram was not given, making it dif fi cult for clinicians to ... See full document

... Results: Of the 106 patients, 71(67%) male and 78(73.6%) patients were <60 years of age. 72(67.9%) presented with B-symptoms, 62(58.5%) had stage III/IV, and 80(75.5%) had high LDH at diagnosis. 22(20.8%) had ... See full document

... following lymphoma response and the absence of multiple myeloma features suggest that the paraprotein was produced by the lymphoma ...center B-cells and is associated with an up-regulation of ... See full document

... many cell lines it appears that response to BCL6 inhibitors correlates with BCL6 levels, in that higher doses are required to suppress cell lines that express more ...firming cell line data showing ... See full document

... malignant lymphoma represents uncommon ...the risk of cardiac failure. Consequently, large numbers of those patients pass away before taking chemotherapy and they are diagnosed ...malignant ... See full document

... A 55-year-old woman was admitted to our hospital with history of dizzy and headache for 1 year. The patient had no B symptoms and her general condition was poor (ECOG performance status =3). Neuroimaging revealed ... See full document

... malignant lymphoma [30]. They concluded that patients with IgG4-related sclerosing disease may be at an increased risk of developing malignant lymphoma ...malignant lymphoma in patients ... See full document

... STAT3 polymorphisms had been shown to be suitable as predictive makers to analyze the response to IFN-α in renal cell carcinoma ...silent polymorphisms could also alter the function of target ... See full document

... or/and polymorphisms of CD20 gene with the response to R-CHOP in diffuse large B cell lymphoma ...or/and polymorphisms in exon5 of CD20 gene were determined ... See full document

... study validated the geographic variations and showed the high frequency of ALCL, ALK-positive in North America, AITL and ETCL in Europe, ATLL in Japan and ENKTCL in Asian countries other than Japan [4]. In fact, the ... See full document

... The Pattern of CD15, CD30 and Bcl 2 Expression in Diffuse Large B Cell Lymphoma ORIGINAL ARTICLE The Pattern of CD15, CD30 and Bcl 2 Expression in Diffuse Large B Cell Lymphoma G I Eow, MPath, L H Kim[.] ... See full document

... called B- cell lymphoma unclassifiable, with features intermedi- ate between diffuse large B-cell lymphoma and Burkitt lymphoma (B-CLU/DLBCL/LB), ... See full document

... Hodgkin Lymphoma (cHL), diffuse large B-cell lymphoma (DLBCL) associ- ated or not with EBV, primary cutaneous anaplastic large cell lymphoma, lymphomatous ... See full document

... neuronal cell membrane ...with large B-cell lymphoma ...articles, large B cell lymphoma with pontine involvement was described [11, ... See full document

... The genetic variants of HATs generally indicate exten- sive deregulation of histone acetylation in B-cell NHL. From a therapeutic perspective, epigenetic therapies such as histone deacetylase (HDAC) ... See full document

... In addition, the expression of c-MET was found in PBMCs from adult T cell leukemia/lymphoma (ATLL) patients and HTLV-1-infected T cell lines. HGF secreted in paracrine rather than in autocrine ... See full document