[PDF] Top 20 Multiple specificities in the murine CD4+ and CD8+ T-cell response to dengue virus.
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Multiple specificities in the murine CD4+ and CD8+ T-cell response to dengue virus.
... purified dengue-2 virus E ...from dengue-4 virus-immunized BALB/c mice did not recognize the dengue-4 virus E protein (42), whereas many of the CD8 1 clones that we ... See full document
7
Analysis of Murine CD8+ T-Cell Clones Specific for the Dengue Virus NS3 Protein: Flavivirus Cross-Reactivity and Influence of Infecting Serotype
... of dengue virus serotype cross- reactivity in short-term T-cell lines and clones differed in mice immunized with different dengue virus ...with dengue type 2 virus ... See full document
6
Differential Targeting of Viral Components by CD4+ versus CD8+ T Lymphocytes in Dengue Virus Infection
... new T cell epitopes in dengue virus patients (9 CD4 ⫹ and 21 CD8 ⫹ T cell epitopes), thus providing new tools for the charac- terization of the phenotype and ... See full document
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Allogeneic Differences in the Dependence on CD4+ T-Cell Help for Virus-Specific CD8+ T-Cell Differentiation
... antiviral CD8 ⫹ effector T cells during acute infection is believed not to require CD4 ⫹ T-cell help, with helper T cells instead being critical for generating and/or maintaining ... See full document
11
Immunomic Analysis of the Repertoire of T-Cell Specificities for Influenza A Virus in Humans
... effector T cells may represent an alternative approach for the generation of a more universal influenza virus ...human T-cell epitopes that would provide broad coverage against different ... See full document
11
Human CD8+ and CD4+ T Cell Memory to Lymphocytic Choriomeningitis Virus Infection
... choriomeningitis virus (LCMV) infection has been well characterized in experimental studies in mice, the T cell response to this virus in humans is incompletely ...specific CD8 ⴙ ... See full document
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Identification of swine influenza virus epitopes and analysis of multiple specificities expressed by cytotoxic T cell subsets
... how CD4 − CD8 + T cell subsets were capable of expressing multiple T cell receptor ligand ...of T cell epitopes con- served across all types, subtypes and ... See full document
5
Identification of Hexon-Specific CD4 and CD8 T-Cell Epitopes for Vaccine and Immunotherapy
... adenovirus-specific T cells may prevent and treat such infections, the T-cell immune response to the multiplicity of adenovirus serotypes and subspecies that infect humans has not been well ... See full document
9
Virus-Specific CD4+ and CD8+ Cytotoxic T-Cell Responses and Long-Term T-Cell Memory in Individuals Vaccinated against Polio
... by murine CD4 and CD8 T cells (17, 21, 23, ...PV-specific T cells in protective immunity in these mice could not be ...PV-specific CD4 T cells into PVR-trans- genic mice ... See full document
8
Epitope Mapping of HIV-Specific CD8+ T Cell Responses by Multiple Immunological Readouts Reveals Distinct Specificities Defined by Function
... of cell- mediated immunity (CMI) responses that may be capable of controlling ...HIV-specific CD8 ⫹ T cell pro- liferation than do progressing controls (11, 30, ...HIV-specific CD8 ⫹ ... See full document
12
Modulation of the CD8+-T-Cell Response by CD4+ CD25+ Regulatory T Cells in Patients with Hepatitis B Virus Infection
... circulating CD4 ⫹ CD25 ⫹ regulatory cells of chronic and resolved ...Unlike murine herpes sim- plex virus (24) and human HCV (23) infection, chronic HBV infection does not appear to be associated ... See full document
7
Comprehensive Analysis of CD8+-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities
... ICS of PBMC (Fig. 3A) and the HLA restriction was demon- strated by establishing a T-cell line (Fig. 3B). Subsequently, truncated peptides were used to determine the minimal pep- tide required for ... See full document
10
Promotion of a Subdominant CD8 T Cell Response during Murine Gammaherpesvirus 68 Infection in the Absence of CD4 T Cell Help
... ␥HV68-specific CD8 T cells in I-Ab ⫺/⫺ mice (11, ...antiviral CD8 T cells in the trigeminal ganglion initially exhibit profound impairment, but over time only the most func- tional cells are ... See full document
8
Dengue virus-specific, human CD4+ CD8- cytotoxic T-cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones.
... DISCUSSION In this article we have reported that i Dengue virusspecific, human CD4+ CD8- T-cell clones are heterogeneous with at least six patterns of virus and serotype specificities; i[r] ... See full document
6
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response
... (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic ...chimeric virus induced a CD8 ... See full document
8
Alterations in T-Cell Receptor Vβ Repertoire of CD4 and CD8 T Lymphocytes in Human Immunodeficiency Virus-Infected Children
... purified CD4 and CD8 populations in 10 umbilical cord blood samples obtained from healthy women following uneventful ...blood CD4 and CD8 T cells showed a * Corresponding author: Savita ... See full document
6
Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype
... against dengue virus (DENV) is poor and hinders the development of a successful human ...DENV-specific CD8 ⴙ T cell responses in general and those of HLA alleles associated with ... See full document
9
Feline immunodeficiency virus infects both CD4+ and CD8+ T lymphocytes.
... In two experimental infections of the CD4+ 3D7 T-cell clone with either the cloned Peeper or Petaluma virus stock, cells infected with the cloned Peeper virus were strongly positive for [r] ... See full document
6
Dengue virus-specific murine T-lymphocyte proliferation: serotype specificity and response to recombinant viral proteins.
... We demonstrated that lymphocytes from mice immunized with dengue 4 virus proliferate in response to a combination of dengue 4 virus C, pre-M, E, NS1, and NS2a proteins expressed in Sf9 c[r] ... See full document
6
CD8+ T Cell Immune Response in Immunocompetent Mice during Zika Virus Infection
... Quantitation of the ZIKV and DENV burden in mice. For viral RNA detection, tissues were homogenized, and total RNA was extracted using TRIzol reagent (Invitrogen). cDNA was prepared from 1 g of RNA using 10 U of avian ... See full document
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