[PDF] Top 20 On-Chip Integrated Label-Free Optical Biosensing

... high-Q optical micro-resoantor is very similar to the measurement of the transmission spectrum of the acetylene gas cell from Section ...and free space coupling using microscope ob- ...techniques, ... See full document

... Beam deflection has the role of addressing the receivers of information in such systems and is best done dynamically; dynamic beam deflection accounts for movement in the network as well facilitating the initial setup. ... See full document

... a label, typically enzymatic, fluorescent or radioactive, which translates the binding event into a quantifiable ...novel, label-free biomarker detection techniques have been demonstrated which allow ... See full document

... Another type of bio-receptors commonly used these days instead of antibodies are aptamers. Aptamers are synthetic oligonucleotide or peptide molecules that reproduce a similar to antibodies function, i.e. specific ... See full document

... the chip design and micro/nanofabrication technologies, “ lab on chip ” biosen- sing devices become a major focus of interdisciplinary research and have attracted signi fi cant attentions globally [3 – ... See full document

... an integrated spectrometer for absorption spectroscopy in the visible region (Ocean Optics, HR4000, ...The optical fiber, with a core size diameter of 50 μm, was aligned precisely onto the center of the ... See full document

... used label-free tests is, the ELISA, which senses an analyte via its binding to an ...sensitive label- free techniques, resulting in a range of new ultra-sensitive techniques including ... See full document

... an optical bus to replace electrical ...an optical NoC, called λ-router, and used WDM ...hybrid optical NoC. [8] proposed a fattree-based optical NoC and integrated the control and data ... See full document

... One of the obstacles to achieving a high sensitivity of LSPR via immunosensors lies in much smaller evanescent field decay length as compared to traditional SPR [14,15]. From that point of view, the use of artificial ... See full document

... Figure 6: a) GO flake movement induced by the Raman laser. Each image represents the change after 10 s exposure time in the order in which they were observed. b) Raman spectra of a GO flake dispersed in liquid crystal E7 ... See full document

... Especially optical techniques have proven interesting for biosensing due to the possibility of rapid and direct (unlabelled) ...in optical biosensors has resulted in a number of sensor devices which ... See full document

... of optical biosensors. Several optical PW biosensor devices developed recently are based on the Mach – Zehnder (MZ) interferometer [11 – 15] and ring resonator [16, 17] principles; both approaches demon- ... See full document

... from label-free biosensing, chemical imaging, surface-enhanced spectroscopies 2 to colour generation 3 ...bulky optical infrastructures such as lasers, prisms and/or microscopes for ...such ... See full document

... in label-free detection, target molecules are not labeled or altered, and are detected in their natural ...forms. Label free optical biosensors are becoming more and more important as ... See full document

... as label-free biosensors [12]. Furthermore, if the optical waveguide properties of NAA are exploited, much higher sensitivities than conven- tional surface plasmon resonance (SPR) sensors [2,13,14] ... See full document

... on integrated optical transducers have demonstrated the analytical performance required for application in different fields ranging from biodiagnostics to environmental monitoring and food ...Moreover, ... See full document

... tify the rate constants. Regarding the latter, I focused on WGMs resonators and on MZIs. e theory provided for the MRRs is quite general, and can be applied also to other topologies (disks, toroids, spheres, etc.). In ... See full document

... plasma (Diener etcher, Femto, 40 % power, 30 s and put in contact with each other, after a drop of methanol had been deposited on one of the surfaces. The methanol was used to give enough time before the bonding takes ... See full document

... varying optical properties in tissue and to image embryo development in greater ...the optical properties mitotic divi- sions inside the opaque early Xenopus embryo [15] and has been successfully applied to ... See full document

... Fig. 1. Detection of dielectric nanoparticles in a nano-fluidic fiber (a) Schematic of the apparatus: light is coupled into the core of the fiber, and particles are pulled into the nanochannel by capillary forces. The ... See full document