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[PDF] Top 20 Original Article The identification of genes associated with NSCLC prognosis based on an integrated bioinformatics analysis

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Original Article The identification of genes associated with NSCLC prognosis based on an integrated bioinformatics analysis

Original Article The identification of genes associated with NSCLC prognosis based on an integrated bioinformatics analysis

... up-regulated genes were ultimately included for further analysis in the aspects of biological function (biological process, cellular component, molecular func- tion) and the KEGG ...These genes were ... See full document

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Original Article Identification of candidate genes and pathways in cisplatin-resistant NSCLC by integrated bioinformatics analysis

Original Article Identification of candidate genes and pathways in cisplatin-resistant NSCLC by integrated bioinformatics analysis

... while expression of PRKCB and RHOF were down-regulated in LUSC. Further survival analy- sis showed that high mRNA expression of NOTCH3 and RHOF were associated with a poor clinical prognosis, while ... See full document

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Original Article Up-regulated iNOS/NOS2 is associated with the poor prognosis of colorectal cancer: an integrated bioinformatics analysis

Original Article Up-regulated iNOS/NOS2 is associated with the poor prognosis of colorectal cancer: an integrated bioinformatics analysis

... hub genes (NOS2, RPS27A, UBC, UBB, EHHADH, ACOX1, AGXT, CAT, PIPOX and IDH1) were identified which were mainly en- riched in the aspects of cancer cell prolifera- tion, migration or ...Survival analysis ... See full document

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Original Article Identification of key genes in preeclampsia-associated trophoblast cells using bioinformatics analysis

Original Article Identification of key genes in preeclampsia-associated trophoblast cells using bioinformatics analysis

... the genes and key pathways associated with invasive trophoblast cells in PE via integrated bioinformatics ...expressed genes (DEGs) between PE trophoblast cell samples and normal ... See full document

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Original Article Identification of molecular target genes and key pathways in nasopharyngeal carcinoma by integrated bioinformatic analysis

Original Article Identification of molecular target genes and key pathways in nasopharyngeal carcinoma by integrated bioinformatic analysis

... of genes in a given ...[6]. Bioinformatics analy- sis has allowed for comprehensive identifica- tion of hundreds of differentially expressed genes (DEGs), molecular pathways, and com- plex ... See full document

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Original Article Identification of key genes associated with idiopathic pulmonary fibrosis using bioinformatics analysis

Original Article Identification of key genes associated with idiopathic pulmonary fibrosis using bioinformatics analysis

... 10 genes with degree ≥ 9 were α 2 type I collagen gene (COL1A2, degree = 17), trans- forming growth factor-β1 (TG- FB1, degree = 17), α 1 type I collagen gene (COL1A1, degree = 16), α 1 type III col- lagen gene ... See full document

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Original Article Identification of differentially-expressed genes in lung squamous cell carcinoma and correlation levels with prognosis through integrated bioinformatics analysis

Original Article Identification of differentially-expressed genes in lung squamous cell carcinoma and correlation levels with prognosis through integrated bioinformatics analysis

... Of the top 120 dysregulated genes, 20 genes were constantly upregulated or downregulated in the 4 datasets [12-15]. The current study fur- ther analyzed the prognostic significance of the 20 constantly ... See full document

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Original Article Identification of potential genes and microRNAs related to recurrence risk of osteosarcoma by miRNA and mRNA integrated analysis

Original Article Identification of potential genes and microRNAs related to recurrence risk of osteosarcoma by miRNA and mRNA integrated analysis

... group. Based on the analysis of the integrated network of DE-miRNAs and DEGs, 11 network modules were ...identified. Based on the neigh- borhood scoring algorithm, the top 100 genes and ... See full document

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Original Article The identification of the key genes and pathways in septic shock using an integrated bioinformatics analysis

Original Article The identification of the key genes and pathways in septic shock using an integrated bioinformatics analysis

... tem of innate immunity. Chong et al. [15] indi- cated that TLRs linking to pattern recognition receptors form a key step in initiating pro- inflammatory signaling pathways, which con- tribute to the further production of ... See full document

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Original Article Identification of genes associated with apoptosis-sensitive acute lymphoblastic leukemia responsive to ionising radiation by bioinformatics analyses

Original Article Identification of genes associated with apoptosis-sensitive acute lymphoblastic leukemia responsive to ionising radiation by bioinformatics analyses

... and Integrated Discovery (DAVID) [15] is a compre- hensive set of functional annotation tool and has been developed for relating the functional terms with gene lists by clustering ...ment analysis, ... See full document

6

Identification of prognosis-related genes and construction of multi-regulatory networks in pancreatic cancer microenvironment by bioinformatics analysis

Identification of prognosis-related genes and construction of multi-regulatory networks in pancreatic cancer microenvironment by bioinformatics analysis

... enrichment analysis of TCGA pancreatic cancer training cohort applied by KOBAS and GSEA, we extracted a list of genes that cor- related with tumor ...These genes were subsequently tested to outline ... See full document

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Identification of key biomarkers associated with cell adhesion in multiple myeloma by integrated bioinformatics analysis

Identification of key biomarkers associated with cell adhesion in multiple myeloma by integrated bioinformatics analysis

... This article is licensed under a Creative Commons Attribution ...the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were ...this article ... See full document

16

Original Article Up-regulation of long non-coding RNA SUMO1P3 is associated with poor prognosis in NSCLC patients

Original Article Up-regulation of long non-coding RNA SUMO1P3 is associated with poor prognosis in NSCLC patients

... with NSCLC, respec- tively. Univariate analysis identified three prog- nosis factors (histological grade (low, middle, or high), TNM stage (I/II, III/IV) and SUMO1P3 expression) that were statistically ... See full document

7

Identification of key genes and pathways using bioinformatics analysis  in septic shock children

Identification of key genes and pathways using bioinformatics analysis in septic shock children

... STRING (version 10.5) database currently covers 9,643,763 proteins from 2,031 organisms. To assess the interactive rela- tionships, the identified DEGs were mapped via STRING, and the experimentally validated ... See full document

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Spatial segregation of the biological soil crust microbiome around its foundational cyanobacterium, Microcoleus vaginatus, and the formation of a nitrogen-fixing cyanosphere

Spatial segregation of the biological soil crust microbiome around its foundational cyanobacterium, Microcoleus vaginatus, and the formation of a nitrogen-fixing cyanosphere

... DNA purification, 16S library preparation, and sequencing DNA from all samples was isolated using a PowerSoil DNA Isolation Kit (MoBio, Carlsbad CA), following the manufacturer’s protocol. General prokaryotic primers ... See full document

12

Eleven genes associated with progression and prognosis of endometrial cancer (EC) identified by comprehensive bioinformatics analysis

Eleven genes associated with progression and prognosis of endometrial cancer (EC) identified by comprehensive bioinformatics analysis

... Interacting Genes Data- base (STRING) to assess protein–protein interaction (PPI) information, and then we used plug-in Molecular Complex Detection (MCODE) to screen hub modules of PPI network in ...functional ... See full document

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Original Article Identification of candidate genes associated with Xiang pig estrus by genome-wide transcriptome analysis

Original Article Identification of candidate genes associated with Xiang pig estrus by genome-wide transcriptome analysis

... that genes with a probility value of ≥8, and a difference of 2 in FPKM value was designated as differently expressed gene to reduce the occurrence of false positives ...of Genes and Genomes (KEGG) for ... See full document

9

Identification of hub genes and therapeutic drugs in esophageal squamous cell carcinoma based on integrated bioinformatics strategy

Identification of hub genes and therapeutic drugs in esophageal squamous cell carcinoma based on integrated bioinformatics strategy

... related genes in ESCC development could predict the OS of ESCC patients ...the genes involved in DNA replication system might be useful markers to predict tumor pro- gression ...downregulated genes ... See full document

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<p>Identification of candidate biomarkers correlated with the diagnosis and prognosis of cervical cancer via integrated bioinformatics analysis</p>

<p>Identification of candidate biomarkers correlated with the diagnosis and prognosis of cervical cancer via integrated bioinformatics analysis</p>

... onco- genes to promote carcinogenesis in a variety of ...comprehensive bioinformatics analysis methods, we found that miRNA16 and miRNA-21 might lead to the pathogenesis of cervical cancer by ... See full document

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Microarray-based identification of genes associated with cancer progression and prognosis in hepatocellular carcinoma

Microarray-based identification of genes associated with cancer progression and prognosis in hepatocellular carcinoma

... Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths [1]. There are 750,000 new cases of HCC and nearly 700,000 deaths each year, making this a particularly lethal form of cancer [2]. Over ... See full document

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