[PDF] Top 20 Patterning the nervous system through development and evolution

... A final discussion was started by Alain Ghysen (University Montpellier) who drew provocative conclusions from some of the previous talks. He first drew on the talk of Nicolas Gompel, not reported in detail in this review ... See full document

... the evolution of the ...and patterning effects they mediate, making them (as we will show below), more decisive for the origination of the Metazoa than the DTFs and the cis-regulatory networks by which they ... See full document

... the nervous system dorsally in higher deuterostomes or ventrally in protostomes depends heavily on the localized production of activities that suppress BMP ...neural patterning mechanisms in the ... See full document

... brain evolution have been raised [4, 5, 8, ...fuse nervous systems, rather than centralized nervous systems ...centralized nervous systems evolved independently between five and nine times [4, ... See full document

... Figure 3 Maximum-intensity projections of confocal laserscanning image stacks providing an overview of the muscle system of a single zooid of Hislopia malayensis . (a) F-actin staining. Solely the parietal muscles ... See full document

... differentiation through cell-cell communication is that it constitutes a dynamic process in which differentiating cells and developing tissues play an active role in setting up the signaling system that ... See full document

... During development, its cells migrate to surround the midline notochord and neural ...segmental patterning, as commonly assumed, and reveal significant phylogenetic diversity in the mechanisms that ... See full document

... sea cucumbers, share many similarities with the tornaria larva of indirectly developing hemichordates. These microscopic larvae have an apical concentration of sero- tonergic neurons [6] and one or two concentrations, or ... See full document

... ENS development relies on reciprocal interactions between ENCCs and their environment that are crucial for ENCC survival, migration, proliferation, patterning and ...ENS development by altering these ... See full document

... 7.1 Posteriorisation of neural tissue by the Wnt/P-catenin signalling pathway In this thesis I have analysed the mechanism by which the Wnt/p-catenin signalling pathway patterns the central nervous system o ... See full document

... Prdm14 controls formation of motor neuron axons The pMN domain gives rise to motor neurons in a process that appears to require Prdm14. In zebrafish, four types of primary motor neurons (one of which is transient) are ... See full document

... in vertebrate and amphioxus neural regionalization is abundant. Very recently, some of us with our collaborators (Albuixech-Crespo et al., 2017) mapped the expression of 48 genes whose orthologs in vertebrates have a ... See full document

... All complex systems have the ability to do something – to accomplish one or more functions. The function of some emer- gent systems is obvious: a sequence of letters communicates a specific idea, a computer algorithm ... See full document

... Our genetic studies indicate that the activities of Egfr and the ac/sc genes converge to specify the fate of MP2 and possibly other NBs. Additional work on genes that regulate NB fate suggests that distinct convergent ... See full document

... limb development as ...normal development of the ...in patterning and epithelial-mesenchymal interactions, not unlike those reported for sonic hedgehog, BMPs and Hox proteins ... See full document

... As pointed out recently, the progressive reinforcement and stabilization of developmental processes will buffer the individual from the effect of mutation, and the population as a whole may therefore carry more genetic ... See full document

... the development of nervous system and mesodermal tissues in chick ...and development, notochord formation and somitogenesis as studied by gross morphology and ...and development was ... See full document

... the development of the cardi- opharyngeal mesoderm between Ciona robusta and Mol- gula occidentalis and found that there were virtually no differences in cell lineage and gene ...developmental system drift ... See full document

... Fig. 5. Endocardial cells promote induction and/or maintenance of a conduction phenotype amongst cardiomyocytes in the murine con- duction system. (A) X-gal staining (blue) of an E13.5 mouse heart from the MC4 ... See full document

... sympathetic nervous system (SNS) from its neural crest (NC) precursors is dependent on BMP signaling from the dorsal ...SNS development, we conditionally knocked out components of the BMP ...SNS ... See full document