[PDF] Top 20 Patterns of CCR5, CXCR4, and CCR3 Usage by Envelope Glycoproteins from Human Immunodeficiency Virus Type 1 Primary Isolates
Has 10000 "Patterns of CCR5, CXCR4, and CCR3 Usage by Envelope Glycoproteins from Human Immunodeficiency Virus Type 1 Primary Isolates" found on our website. Below are the top 20 most common "Patterns of CCR5, CXCR4, and CCR3 Usage by Envelope Glycoproteins from Human Immunodeficiency Virus Type 1 Primary Isolates".
Patterns of CCR5, CXCR4, and CCR3 Usage by Envelope Glycoproteins from Human Immunodeficiency Virus Type 1 Primary Isolates
... coreceptor usage profiles and fusion specificities for natural target cells: evidence for functional CXCR4 on ...Envs from the primary isolates to mediate fusion with natural hu- man ... See full document
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CCR5 and CXCR4 Usage by Non-Clade B Human Immunodeficiency Virus Type 1 Primary Isolates
... of CCR5 were assessed for their ability to mediate the entry of six non-clade B R5 isolates: ...six isolates was strongly dependent on residues Y10, D11, Y14, Y15, and E18 ...by CCR5 mutants. ... See full document
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Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates, Like HIV-1 Isolates, Frequently Use CCR5 but Show Promiscuity in Coreceptor Usage
... use CCR5 as a coreceptor for entry, regardless of other phenotypic properties ...HIV-2 envelope glycoproteins, like those of HIV-1 and SIV, are able to use CCR5 as a coreceptor for ... See full document
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The CCR5 and CXCR4 Coreceptors Are Both Used by Human Immunodeficiency Virus Type 1 Primary Isolates from Subtype C
... have envelope glycoproteins that are atypical in structure or function compared to viruses from other HIV-1 ...C envelope glycoproteins might, in principle, help to explain why ... See full document
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Chemokine Coreceptor Usage by Diverse Primary Isolates of Human Immunodeficiency Virus Type 1
... subset usage by diverse, well-characterized primary viruses isolated from peripheral blood by monitoring viral replication with CCR1, CCR2b, CCR3, CCR5, and CXCR4 ...lines. ... See full document
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Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype.
... All primary isolates tested were able to induce syncytia pro- vided that the cells expressed the particular coreceptor used by the ...two virus isolates (isolates 25 and J2822) were ... See full document
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A Quantitative Affinity-Profiling System That Reveals Distinct CD4/CCR5 Usage Patterns among Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Strains
... of human immunodeficiency virus (HIV) envelope for CD4 and CCR5 appears to be associated with aspects of R5 virus (virus using the CCR5 coreceptor) ...results ... See full document
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Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates Infect CD4-Negative Cells via CCR5 and CXCR4: Comparison with HIV-1 and Simian Immunodeficiency Virus and Relevance to Cell Tropism In Vivo
... the envelope glycoproteins form a subtly different con- formation compared to HIV-1, where the 7TM binding site on gp120 is at least partially exposed or formed, enabling direct contact without ... See full document
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Glycosphingolipids Promote Entry of a Broad Range of Human Immunodeficiency Virus Type 1 Isolates into Cell Lines Expressing CD4, CXCR4, and/or CCR5
... influenza virus HA-medi- ated fusion of liposomes containing a specific GSL with the target ...HIV-1 envelope glycoprotein-mediated fusion following incorporation of GSLs using our method (data not ... See full document
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Neutralization Profiles of Primary Human Immunodeficiency Virus Type 1 Isolates in the Context of Coreceptor Usage
... of human immunodeficiency virus type 1 (HIV-1) which have only been carried in vitro in peripheral blood mononuclear cells (primary isolates) can be neutralized by ... See full document
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Exclusive and Persistent Use of the Entry Coreceptor CXCR4 by Human Immunodeficiency Virus Type 1 from a Subject Homozygous for CCR5 Δ32
... used CCR5, BOB, and Bonzo. Exclusive CXCR4 usage was confirmed for the 12/85 and 6/86 viral chimeras and 6/94 plasma isolate in a ...which CXCR4, CCR1, CCR2B, CCR3, CCR4, and ... See full document
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Tissue-Specific Sequence Alterations in the Human Immunodeficiency Virus Type 1 Envelope Favoring CCR5 Usage Contribute to Persistence of Dual-Tropic Virus in the Brain
... of CCR5 or CXCR4, re- spectively, for HIV-1 ...via CCR5. Importantly, we showed that brain-derived R5X4 Envs can use CCR5 for HIV-1 entry into primary cells including MDM, ... See full document
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Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.
... of envelope pro- teins are known to make significant contributions to Env tro- pism (13, 20, 29, 38), and since the V3 region makes a major contribution to coreceptor specificity (14), we reasoned that charged ... See full document
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Cytopathicity of Human Immunodeficiency Virus Type 1 Primary Isolates Depends on Coreceptor Usage and Not Patient Disease Status
... longitudinally from four patients who exhibited significant disease progression but never developed detectable X4 viremia or who were treated with antiretroviral ...of CCR5 (patients A and B) (Table ... See full document
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Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates
... of envelope genes from HIV-infected brains may clarify the po- tential role of these other coreceptors, since it does not intro- duce the selection bias associated with viral isolation ...that CCR3, ... See full document
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In Vivo Distribution of the Human Immunodeficiency Virus/Simian Immunodeficiency Virus Coreceptors: CXCR4, CCR3, and CCR5
... viral envelope proteins and specific cellular ...the primary recep- tor for human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) and simian immunodeficiency ... See full document
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Identification of Determinants on a Dualtropic Human Immunodeficiency Virus Type 1 Envelope Glycoprotein That Confer Usage of CXCR4
... chimeric envelope proteins (expressed by transfecting pNVVDH120A to -I) with cells expressing CCR5 or CXCR4 in conjunction with CD4 was ...identical patterns of coreceptor usage for ... See full document
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Role of N-linked glycans of envelope glycoproteins in infectivity of human immunodeficiency virus type 1.
... Because recombinant proteins may display properties that are different from those of viral proteins in solution or included in the viral envelope, we have investigated here whether immun[r] ... See full document
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Molecular Basis for Cell Tropism of CXCR4-Dependent Human Immunodeficiency Virus Type 1 Isolates
... a CXCR4-specific inhib- itor of HIV-1 infection (12), while replication of NL-ADA preceded normally in the presence of AMD3100 ...PR-R5-derived virus NL-ADA failed to replicate in these cells, which ... See full document
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CXCR4 as a Functional Coreceptor for Human Immunodeficiency Virus Type 1 Infection of Primary Macrophages
... only CXCR4 among the identified ...use CXCR4 for infection of PBMCs and dendritic cells since SDF-1 is an ef- ficient inhibitor of infection (3, 18, ...that CXCR4 is expressed on ... See full document
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