[PDF] Top 20 Programmed cell death in mouse primordial germ cells
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Programmed cell death in mouse primordial germ cells
... onto cell feeder layers producing mem- brane bound ...migrating mouse PGCs by reducing their apoptotic rate via MEK/ERK ...expecting, mouse PGCs carrying a constitutively activating Kit mutation ... See full document
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The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse
... Here, we describe for the first time the defects caused by Blimp1 loss of function in the mouse. Blimp1-deficient embryos die at mid-gestation, but surprisingly early axis formation, anterior patterning and neural ... See full document
11
Mouse primordial germ cells produce cysts that partially fragment prior to meiosis
... of primordial follicles ...original cell. The oocyte normally forms from the most downstream cell, which is the initial cell in 16-cell Drosophila ...one cell that is still ... See full document
7
Identification of X-Linked Genes Required for Migration and Programmed Cell Death of Drosophila melanogaster Germ Cells
... disrupts germ cell migration, and the germ cells ectopic to the gonad fail to undergo programmed cell ...rescues germ cell migration, but not the germ ... See full document
12
Characterization of three spot, a mutation that disrupts germ cell migration of Drosophila melanogaster
... few primordial germ cells persist inside the gut or near the midgut epithelium; however, a tspt mutant embryo continues to have an average of 6 germ cells expressing Vasa in the gut at ... See full document
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Primordial germ cells: the first cell lineage or the last cells standing?
... that cell-intrinsic events governing the specification of human PGCs are also different from those in mice, at least based on the results of in vitro ...PGC-like cells derived from human embryonic stem ... See full document
10
Primordial germ cell migration
... pole cells (1), emigration of PGCs from the gut (2), lateral migration of PGCs (3) and gonad coalescence (4) ...pole cells into the hindgut pocket (see above). Loosening of cell-cell contacts ... See full document
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Interleukin 2 induces the proliferation of mouse primordial germ cells in vitro
... obtained cell suspension was filtered using a nylon net (Falcon; BD Biosciences, Heidelberg, Germany) to remove cell aggregates and was centrifuged at 390 g for 10 ...somatic cells, cell ... See full document
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Epigenetic reprogramming in mouse pre implantation development and primordial germ cells
... adult mouse brain (Guo et ...cultured cell lines, and this requires the BER ...B cells, such as processivity, sequence selectivity, transcription dependence and strand ... See full document
17
Spermatogenesis from epiblast and primordial germ cells following transplantation into postnatal mouse testis
... Donor cells were collected from pregnant C57BL/6 mice that were maintained in a controlled environment with 12:12 light:dark cycles from ...transgenic mouse line C57BL/6 Tg14 (act- EGFP) OsbY01 (designated ... See full document
6
How to make a primordial germ cell
... in mouse germ cell biology, which will provide the basis for studies on germ cells of other mammalian species, including ...the germ cell genes and in the initiation of ... See full document
8
A replication dependent passive mechanism modulates DNA demethylation in mouse primordial germ cells
... Germline cells reprogramme extensive epigenetic modifications to ensure the cellular totipotency of subsequent generations and to prevent the accumulation of ...Notably, primordial germ cells ... See full document
12
Programmed cell death is not a necessary prerequisite for fusion of the fetal mouse palate
... of cells in adult tissues (Glücksmann, 1951; Saunders, 1966; Wyllie et ...some cells are eliminated by means of PCD to achieve complicated ...unnecessary cells, (3) controlling cell numbers in ... See full document
8
The distribution and behavior of extragonadal primordial germ cells in Bax mutant mice suggest a novel origin for sacrococcygeal germ cell tumors
... extragonadal germ cells were counted and scored based upon location and combinations of positive immunofluorescent signals, us- ing Zeiss LSM Imaging ...Scp3-positive germ cells were ... See full document
12
SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling
... In this study, we focused on another candidate, SETDB1, which catalyzes the tri-methylation of lysine 9 (K9) of histone H3 and was identified by RNAi screening. Methylated K9 of histone H3 is a repressive epigenetic ... See full document
10
Impaired meiotic competence in putative primordial germ cells produced from mouse embryonic stem cells
... oocyte-like cells were surrounded by one to two layers of flattened cells and did not have a visible zona pellucida; oocyte-specific markers, such as Fig and Zp3, were expressed by the ovarian ... See full document
9
Differentiation of mouse primordial germ cells into female or male germ cells
... 4 days, followed by a decrease in number on day 5. It was noticed that PGCs in culture change their morphology according to their age and culture period. We divided the morphology of PGCs into three categories and ... See full document
8
Programmed cell death of primordial germ cells in Drosophila is regulated by p53 and the Outsiders monocarboxylate transporter
... PGC death is mediated by p53 and out We provide evidence that p53 and out are required for the elimination of excess PGCs in the early stages of Drosophila ...gonads. Germ cell movements are not ... See full document
10
Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
... All animals were treated according to protocols approved by the Institutional Animal Care and Use Committee at Cincinnati Children’s Hospital. Mouse embryos were obtained by crossing males homozygous for the ... See full document
9
Regulation of primordial germ cell development in the mouse
... ABSTRACT Primordial germ cells (PGCs) are the founders of the ...of primordial germ ...post-migratory mouse PGCs devised in the author’s laboratory are first briefly ...suitable ... See full document
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